Coolio
Greenlighter
- Joined
- Feb 29, 2004
- Messages
- 6,946
There is a long thread in ADD about this. The jury is still out but there was one study conducted on rats I believe where they did a test that checked if it (or its metabolites) destroyed DNA which would suggest it is carcinogenic. It wasn't found to destroy DNA in this test so thats good. Apparently the person who sponsored the studies and provided the results wish to remain anonymous though so that doesn't say much for credibility.
You can find the test here: http://www.synchronium.net/2009/02/21/jwh-018-toxicology/
Edit: This is for -018 but they both have similar structures with the potential to metabolize into a toxic chemical.
What study are you referring to?
There was a study done on JWH-015, not JWH-018, which showed that there is an epoxide intermediate that is created during the metabolism of the compound in rats or mice. There was no study done on the carcinogenicity of JWH-015 or the epoxide intermediate, nor is the epoxide likely to exist within an animal's cells for any considerable amount of time. There's also no evidence that JWH-018 shares metabolites with JWH-018. There was simply speculation here on Bluelight that the epoxide intermediate metabolite of JWH-015 might be carcinogenic. Some people took that and ran with it all the way to "JWH-018 causes cancer."
The study I am thinking of doesn't mention cancer or DNA at all I don't believe.