Published Behavioral Naltrexone Therapy (BNT) Vs. Naltrexone Implant (NYC)

nuke

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Behavioral Naltrexone Therapy (BNT) for Promoting Adherence to Oral Naltrexone (BNT-Oral) vs Extended Release Injectable Depot Naltrexone (Depot-BNT); a Randomized Trial. A Free Treatment for Opiate Abuse.

In pilot study now proposed, we plan to randomly assign 60 opioid dependent patients to the new model, Depot-BNT, or to BNT plus oral naltrexone for a 6-month trial. This will provide initial clinical experience with the new Depot-BNT treatment model, while providing a rigorous test of whether Depot-BNT produces superior treatment outcome, compared to our best behavioral platform for oral naltrexone (BNT).

The following aims will be addressed:

Specific Aim #1: To test whether Depot-BNT increases retention in treatment and improves drug use outcome (urine-confirmed abstinent weeks) compared to our established model of BNT with oral naltrexone (BNT-Oral), and to explore whether Depot-BNT (vs BNT-Oral) improves key secondary outcomes including dysphoria, HIV risk behavior, and social functioning. Specific Aim #2: To explore predictors of outcome on Depot-BNT, and mechanisms of attrition, in order to optimize Depot-BNT prior to further testing.

Estimated Enrollment: 60
Study Start Date: September 2007
Estimated Primary Completion Date: August 2011 (Final data collection date for primary outcome measure)

Contacts
Contact: Julianne Kurtz, BA 212 923-3031 [email protected]
Contact: daniel brooks, MA 212 923-3031 [email protected]

Locations
United States, New York
New York State Psychiatric Institute Recruiting
New York, New York, United States, 10032
Contact: Julianne Kurtz [email protected]
Contact: Elizabeth Martinez 212 923-3031 [email protected]
Principal Investigator: Maria Sullivan, MD

http://clinicaltrials.gov/ct2/show/NCT00577408
 
Last edited by a moderator:
This one has closed for recruitment:

This study is ongoing, but not recruiting participants.
Study NCT00577408 Information provided by National Institute on Drug Abuse (NIDA)
 
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