Getting around the timerx... finally---
I had a method of dealing with old Endo morphine tablets which worked well. I would mix 1.5cc with crushed pill, stir up into a gel, push in into the middle of spoon, add another 1.5cc of water to it (WITHOUT STIRRING FURTHER. Then I would cook it on low heat (LOW HEAT). this gel would not mix or expand into the other 1.5CC of water, and after about 3 minutes I would draw it off with micron filter. then I would add another 1.5cc pf water and repeat. This would leave me with a glob of gel in the spoon, and 3cc of what I would imagine was 70 - 95% of the morphine in the tablet. It took all of four or five minutes, and it circumvented all the problems I kept hearing about. (the low heat helps the molecules to osmose faster into what they are more freely soluble in--the water on top. after a few filters, I felt fairly safe doing this... I am not sure if anyone has tried this with Opana ER, but I would be interested to hear about it.
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but that is besides the point-
I have three degrees right now (writing, communications, sociology--but I started off pre-med), my best friend has a M.S. in chemical engineering, and I live in academia. This Opana problem seems fairly easy to deal with, and I think that a lot of people have touched on possible ways to pull it off. There just needs to be a little revision:
Opana Extended Release contains these chemicals—
See (
http://www.endo.com/pdf/Opana_ER_PI.pdf)
Lets talk some really basic chemistry—solubility.
Here’s where the problem happens— (remember, this is all room temperature)
Oxymorphone – freely soluble in water, slightly/partially soluble in ETOH.
TIMERx® -N: (The hard one RIGHT?)
Locust Gum: freely soluble in water (gels up), INSOLUBLE in ETOH
Xanthan Gum: freely soluble in water (gels up), INSOLUBLE in ETOH
You mix opana with water first, you get a spoon full of cum.
Here’s where we can build a plan of action:
Here are some other things that are insoluble in ETOH:
TIMERx® -N: (The hard one RIGHT?)
Locust Gum: freely soluble in water (gels up), INSOLUBLE in ETOH
Xanthan Gum: freely soluble in water (gels up), INSOLUBLE in ETOH
hypromellose: insoluble in dehydrated ethanol
The 5 mg, 10 mg, 15 mg, 20 mg, and 30 mg tablets also contain
Macrogol: freely soluble in water, practically insoluble in ETOH
Oxymorphone – freely soluble in water, slightly/partially soluble in ETOH.
Other TIMERx ingredients:
Dextrose: doesn’t matter because its harmless
Polysorbate: freely soluble in water and ETOH, but harmless (used in eye drops)
methylparaben: soluble in ethanol and H2O, but is a preservative and, IMHO, harmless
sodium stearyl fumarate: Practically insoluble in water, slightly soluble in Ethanol.
Insoluble\poorly soluble in Water:
titanium dioxide: insoluble in water
Calcium Carbonate [chalk, TUMS] poorly soluble in water (47mg/liter) and harmless also.
triacetin: soluble in ETOH, slightly soluble in water, insoluble in benzene
SO—since oxymorhpone is partially soluble in ethanol (about .25-.5 grams per liter) you are going to need a nice amount of pure ethanol here. Four a 40mg pill—I would go use at least 50 milliliters since it evaporates so quickly. Crush up very finely the pill. Mix this in with at least everclear (preferably >99% ETOH). Let sit for a while. Sediment at the bottom will include TIMERx and hypromellose. Filter the sediment out.
Now have ETOH containing your oxymorphone, very little macrogel, dextrose, polysorbate, sodium steryl fumerate, methylparaben, titanium dioxide, calcium carbonate, and tums.
Now find a flat easily scrapable glass or pyrex dish. Let the alcohol evaporate.
Afterwards mix the left over powder in the plate with cold/lukewarm water.
Sodium steryl fumerate isn’t soluble in water—neither is titanium dioxide, for the most part calcium carbonate and triacetin. Oxymorphone is freely soluble, along with dextrose, polysorbate, the residual macrgel, methylparaben. a little bit of triacetin.
So What does this mean?
After you filter off the sediment that isn’t soluble in the water, you have a aqueous solution of oxymorphone, and a few other harmless substances (preservatives).
(If you want to go all crazy, Triacetin is insoluble in Benzene, but I think that’s going overboard. Just be careful with dosing—also, use ETOH, and not rubbing alcohol. It you get to fiending out, injecting etoh (while it burns) will not harm you like isopropyl alcohol will… just a thought.)
Again---I talked with my friend and wrote this in two hours. I have high hopes and would try it myself if I have one on hand. Should anyone find this works, please let me know. I have high faith in the process. It is after all just a matter of patience and science.
so to summarize:
1. scrape of coating with sandpaper preferably
2. crush pill and mix in glass with 50-100ml of >95% ETOH (5-10 min)
3.Let sediment settle then filter out ETOH
4. Let ETOH Evaporate.
5. Add water to solution.
6. let sediment settle, then filter off H20.
7. MEASURE DOSAGE.
8. Enjoy Responsibly.
Be well- be safe.
pragma.