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Bluelighter
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Naltrexone and Adrenergic Agents to Reduce Heroin Use in Heroin Addicts
Naltrexone is a medication that is currently used to treat drug and alcohol addiction. Guanfacine is a medication that is currently used to manage the withdrawal symptoms in individuals undergoing opioid detoxification. A combination of these two medications may be beneficial in reducing heroin use in individuals addicted to heroin. This study will evaluate the effectiveness of naltrexone and guanfacine, alone and in combination, at reducing heroin use in heroin addicts.
Estimated Enrollment: 280
Study Start Date: February 2006
Estimated Study Completion Date: July 2010
Estimated Primary Completion Date: July 2010 (Final data collection date for primary outcome measure)
Locations
Russian Federation
Saint Petersburg Pavlov State Medical University Recruiting
Saint Petersburg, Russian Federation
Contact: Evgeny Krupitsky, MD, PhD 203-932-5711 ext 7438
More Information
Responsible Party: Baylor College of Medicine ( Thomas Kosten, MD )
Study ID Numbers: NIDA-18863, DPMC, R01-18863
Study First Received: September 1, 2005
Last Updated: March 10, 2009
ClinicalTrials.gov Identifier: NCT00142948 History of Changes
Health Authority: United States: Federal Government
http://clinicaltrials.gov/ct2/show/NCT00142948
Naltrexone is a medication that is currently used to treat drug and alcohol addiction. Guanfacine is a medication that is currently used to manage the withdrawal symptoms in individuals undergoing opioid detoxification. A combination of these two medications may be beneficial in reducing heroin use in individuals addicted to heroin. This study will evaluate the effectiveness of naltrexone and guanfacine, alone and in combination, at reducing heroin use in heroin addicts.
Estimated Enrollment: 280
Study Start Date: February 2006
Estimated Study Completion Date: July 2010
Estimated Primary Completion Date: July 2010 (Final data collection date for primary outcome measure)
Locations
Russian Federation
Saint Petersburg Pavlov State Medical University Recruiting
Saint Petersburg, Russian Federation
Contact: Evgeny Krupitsky, MD, PhD 203-932-5711 ext 7438
More Information
Responsible Party: Baylor College of Medicine ( Thomas Kosten, MD )
Study ID Numbers: NIDA-18863, DPMC, R01-18863
Study First Received: September 1, 2005
Last Updated: March 10, 2009
ClinicalTrials.gov Identifier: NCT00142948 History of Changes
Health Authority: United States: Federal Government
http://clinicaltrials.gov/ct2/show/NCT00142948
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