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    Pharmaceutical drugs analagous to Cocaine 
    #1
    Hey everyone,

    So recently i've taken a real liking to very clean cocaine (I believe its one of the cleanest I've had in a while) however, due to expenses (damn the recession) I was considering switching to a prescription drug that emulated the upper high.

    So i was wondering,

    Are there any pharmaceutical drugs that are similar to cocaine in terms of its effects? im aware of ritalin and adderal and etc, but there seems to be many opinions on their differences. So by experience, which do you think is the closest?

    and second of all, pertaining to the chemical structure, which pharma drug is the most similar?

    Thanks
     

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    #2
    Bluelighter Binge Artist's Avatar
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    In terms of chemistry, I'd guess the closest matches will be the other "caines" (ie, lidocaine, procaine, novacaine, etc). But those will only have the anesthetizing effects. As far as getting a pharm with the cocaine high? Sounds like a tough one.
     

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    #3
    I took adderall for years and i think it is very similar to coke in many ways. there is no drug exactly like coke. but amphetamines IMO are more similar to coke than they are different.

    if you like coke i dont see why you would not like adderall. it makes you feel good thats for sure, but it lasts a lot longer.
     

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    #4
    Quote Originally Posted by melarsoprol View Post
    Hey everyone,

    So recently i've taken a real liking to very clean cocaine (I believe its one of the cleanest I've had in a while) however, due to expenses (damn the recession) I was considering switching to a prescription drug that emulated the upper high.

    So i was wondering,

    Are there any pharmaceutical drugs that are similar to cocaine in terms of its effects? im aware of ritalin and adderal and etc, but there seems to be many opinions on their differences. So by experience, which do you think is the closest?

    and second of all, pertaining to the chemical structure, which pharma drug is the most similar?

    Thanks
    in terms of both chemical structure as well as pharmacological action, methylphenidate (ritalin) is the prescription stimulant most similar to cocaine. i think most people would agree that ritalin isn't nearly as enjoyable. in fact, some people feel downright crappy on the stuff. personally, I think it feels pretty similar to coke, but i have only ever gotten low quality cocaine so it's hard to judge. although i have never tried it, the more active isomer, dextromethylphenidate (focalin) is said to be much more pleasant and coke-like than ritalin.

    but, i think most people who have used prescription stimulants would agree that amphetamines are probably the best. dextroamphetamine (dexedrine) would be most desirable, but Adderall (mixed amphetamine salts) is still pretty good, and more widely available. it's also worth mentioning that there are prescription methamphetamine tablets (desoxsyn), but they are rarely prescribed.
     

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    #5
    Quote Originally Posted by Binge Artist View Post
    In terms of chemistry, I'd guess the closest matches will be the other "caines" (ie, lidocaine, procaine, novacaine, etc). But those will only have the anesthetizing effects. As far as getting a pharm with the cocaine high? Sounds like a tough one.
    if we are just considering chemical structure that's not limited to stimulants, atropine is suprisingly cocaine like. it share no similarities in effect though.
     

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    #6
    Bluelighter Binge Artist's Avatar
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    OK, curiosity's gotten the best of me. Why do you want a pharm that's similar to coke? Why not just get...coke?
     

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    #7
    Thank you for the quick replies.

    Well basically, cocaine is always a gamble. the quality, the buying, the laws, the risk the list goes on.

    However, seems like i have a knack for getting prescription drugs with docs, and i have some sort of ADD/bi-polar so i believe this can be more than just an outlet for abuse. Basically, im doing this on the basis of cost, because i have a pretty nice health insurance, might as well use it.

    Do people recreationally use the caine? I've never heard of this, but maybe this is promising. I know lidocaine is too weak for any recreational use though.
     

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    #8
    Quote Originally Posted by melarsoprol View Post
    Do people recreationally use the caine? I've never heard of this, but maybe this is promising. I know lidocaine is too weak for any recreational use though.
    no. besides ending in -caine and being local anasthetics, lidocaine, benzocaine etc have nothing to do with cocaine. their chemical structures aren't even similar to coke. too much local anasthetics in the bloodstream can stop your heart, so dont try to take a bunch.
     

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    #9
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    Ya the "caines" are structurally similar i think but don't readily cross the Blood Brain Barrier...Amphetamines have similar stimulating effects but don't really have that spark and just aren't the same...Adderall (amphetamine salts), Dexidrine (single amp salt), and Dysoxyn (pharm grade meth-amp) might be what you're looking for but they are all amps so you might like it or might not...They are pretty euphoric but still different from coke...

    And there is pharm. grade coke but good luck finding that...(unless you work in a hospital or something)
     

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    #10
    'due to expenses, damn the recession'
     

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    #11
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    coke is coke for a reason, can't duplicate that feeling but you can mimic it with amphs in pill form. Coke must be more cost effective for the govt to keep illegal rather than lowering the status of it scheduling right under marijuana as the worst drug lol
     

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    #12
    Bluelight Crew jackie jones's Avatar
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    The chemical structure of Cocaine is very close to that of Methylphenidate (Ritalin), more so than most pharmacutical drugs. Ritalin works in a similar way as cocaine, more so than any pharmacutical, causing an overflow of dopamine, which causes euphoria when in effect, and a shortage of dopamine when the drug is ceased, which leads to dysphoria and addictive behavior.



    Last edited by jackie jones; 27-02-2009 at 04:10.
     

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    #13


    Technically its similar in action (its a DNRI like coke and mph are), but not so much in effect. What I mean by that is its far from recreational. Its disgusting enough to take at prescription doses; I couldn't imagine trying to get high on this trash.
     

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    #14
    Bluelight Crew jackie jones's Avatar
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    It feels like cocaine when IV'd and insufflated (insufflated in higher doses, that is. I'd say that 60mg is comparable to a couple lines of good cocaine), ie increased concentration and euphoria. Cocaine is more intense and has a quicker duration, in lower doses.

    IV methylphenidate is extremely bad for your cardiovascular system. Possible heart attack.

    Insufflated methylphenidate is a bad rush to your Central Nervous System, and leads to deterioration of the sinuses.
     

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    #15


    Atropine



    Cocaine

    much more similar chemically than cocaine/ritalin.
     

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    #16
    Quote Originally Posted by melarsoprol View Post

    Are there any pharmaceutical drugs that are similar to cocaine in terms of its effects? im aware of ritalin and adderal and etc, but there seems to be many opinions on their differences. So by experience, which do you think is the closest?

    and second of all, pertaining to the chemical structure, which pharma drug is the most similar?

    Thanks
    Methylphenidate is the only pharmaceutical drug anything like cocaine. It is not nearly as effective at increasing dopamine levels in the crucial parts of the brain responsible for euphoria, but it works in the "same way" as a dopamine reuptake inhibitor.

    Amphetamines work in a completely different manner, by causing dopamine, serotonin, and norepinephrine release while also reversing the dopamine transporter in some individuals. Amphetamine and meth are also euphoric dopaminergic stimulants but the 'high' is completely different. About as different as cocaine and MDMA.

    There is also the drug MDPV which is an unscheduled research chemical that works in the same basic ways as cocaine and methylphenidate. MDPV lies somewhere between the two in terms of spectrum of effects.
     

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    #17
    Quote Originally Posted by melarsoprol View Post
    Thank you for the quick replies.

    Well basically, cocaine is always a gamble. the quality, the buying, the laws, the risk the list goes on.

    However, seems like i have a knack for getting prescription drugs with docs, and i have some sort of ADD/bi-polar so i believe this can be more than just an outlet for abuse. Basically, im doing this on the basis of cost, because i have a pretty nice health insurance, might as well use it.

    Do people recreationally use the caine? I've never heard of this, but maybe this is promising. I know lidocaine is too weak for any recreational use though.
    Keep that shit to yourself, because as a fellow ADD suffer the last thing I like to hear is someone saying they'll go doctor shopping to get ADD meds to fill the gap. People like you, make it difficult for all us ADD sufferers to get our meds. So coke is expensive, so your next best option is to screw ADD sufferers over by pretending to have ADD? I dont want to hear that. And many others agree, so keep that shit to yourself mate.
    You wont find another cocaine-like drug unless you're a chemical engineer.
    Do some research..,. Wikipedia has loads of analogs (all scheduled under Analog Act no doubt), and Advanced Drug Discussion can help too.
    But if youre lloking for meds to get via doc shopping youre treading a thin line and I'll close it if needs be.
    Sorry to sound a but harsh but the more I go back to get my scripts filled, the more I notice the difficulties you potential doc shoppers have caused me in everyday life. Use coke. Can't afford it, then ration it. Or dont use. But going to get an RX for Ritalin or whatever really annoys me.
    Keep your post centred to cocaine analogs and the post will stay productive and it wont be locked.
    Just consider the real people who really need the meds... not to get high, but to get by...
     

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    #18
    Its really too bad about people doc shopping for meds and then abusing them ect. I never used to care much about it until I ran into some serious problems of my own--and found it very hard to get anything perscribed--not in any attempt to get high but to find relief.
     

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    #19
    Bluelighter delta_9's Avatar
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    Quote Originally Posted by melarsoprol View Post
    Hey everyone,

    So recently i've taken a real liking to very clean cocaine (I believe its one of the cleanest I've had in a while) however, due to expenses (damn the recession) I was considering switching to a prescription drug that emulated the upper high.

    So i was wondering,

    Are there any pharmaceutical drugs that are similar to cocaine in terms of its effects? im aware of ritalin and adderal and etc, but there seems to be many opinions on their differences. So by experience, which do you think is the closest?

    and second of all, pertaining to the chemical structure, which pharma drug is the most similar?

    Thanks
    Cocaine, as we all know, is a stimulant. There are many stimulants and amphetamines used in medicine, but IMO cocaine is an atypical stimulant and most other stims/amphets fall short.
    I suppose the compounds most similar in structure to cocaine would be the other tropane alkaloids found in the coca plant. Of course these are inactive though.
     

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    #20
    Quote Originally Posted by djsim View Post
    Keep that shit to yourself, because as a fellow ADD suffer the last thing I like to hear is someone saying they'll go doctor shopping to get ADD meds to fill the gap. People like you, make it difficult for all us ADD sufferers to get our meds. So coke is expensive, so your next best option is to screw ADD sufferers over by pretending to have ADD? I dont want to hear that. And many others agree, so keep that shit to yourself mate.
    That's not doctor shopping. Doctor shopping is going to multiple doctors and failing to mention that you're already being prescribed drugs from the first doctor(s) to get more prescriptions. When people are basically forced to go through doctors to access drugs like methylphenidate and amphetamine, it's within our rights as patients and customers to take our business elsewhere if the provider doesn't give us what we demand.
     

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    #21
    Bluelighter delta_9's Avatar
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    Not 100% sure, but I do know some pharmaceutical cocaine is extract. For example, the coca cola company imports bulk coca leaves, extracts the cocaine and sells it to pharmaceutical companies before using the leaves to flavor their soda.
     

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    #22
    It's from the plant.
     

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    #23
    http://query.nytimes.com/gst/fullpag...pagewanted=all

    How Coca-Cola Obtains Its Coca

    July 1, 1988
    How Coca-Cola Obtains Its Coca
    By CLIFFORD D. MAY

    LEAD: For years people have speculated about the secret formula of Coca-Cola, and the ingredients its contains. The formula has been locked in a bank vault, and only a few executives can see it.

    For years people have speculated about the secret formula of Coca-Cola, and the ingredients its contains. The formula has been locked in a bank vault, and only a few executives can see it.

    Coca-Cola, the world's best-selling soft drink, once contained cocaine, and it is still flavored with a non-narcotic extract from the coca, the plant from which cocaine is derived.

    This week, details of how Coca-Cola obtains the coca and how it is processed emerged from interviews with Government officials and scientists involved in drug research programs. They identified the Illinois-based Stepan Company as the importer and processor of the coca used in Coke. After Stepan officials acknowledged their ties to Coca-Cola, the soft drink giant confirmed those details of its operations. Coca-Cola's Comment

    In a telephone interview from Coca-Cola's Atlanta headquarters, Randy Donaldson, a company spokesman, said, ''Ingredients from the coca leaf are used, but there is no cocaine in it and it is all tightly overseen by regulatory authorities.''

    Emanuel Goldman, a beverage industry analyst at Montgomery Securities in San Francisco, commented: ''This is old hat to people in the industry, but might come as a surprise to others. But it also makes sense: when you have a good product you change it as little as possible.''

    The first batch of Coca-Cola was brewed in 1886 by John Styth Pemberton, a pharmacist, who described the product as a ''brain tonic and intellectual beverage.'' The original recipe included coca with cocaine, but the narcotic was removed just after the turn of the century, according to company spokesmen.

    Cans and bottles of Coca-Cola list only ''natural flavors,'' in addition to water, high-fructose corn syrup and/ or sucrose, caramel color, phosphoric acid and caffeine.

    A Stepan laboratory in Maywood, N.J., is the nation's only legal commercial importer of coca leaves, which it obtains mainly from Peru and, to a lesser extent, Bolivia.

    Besides producing the coca flavoring agent for Coca-Cola, Stepan extracts cocaine from the coca leaves, which it sells to Mallinckrodt Inc., a St. Louis pharmaceutical manufacturer that is the only company in the United States licensed to purify the product for medicinal use.

    During the 1980's, imports of coca by Stepan have ranged from 56 metric tons to 588 metric tons a year, according to figures from the Drug Enforcement Administration.

    Some coca cultivation is still permitted in Peru, where coca leaves have been both chewed and brewed into teas for centuries. However, the United States has been pressuring Peru and other countries to eradicate the plant and substitute other crops.

    Mr. Donaldson declined to discuss whether the Reagan Administration's planned attempt to reduce South American coca growing could have an impact on the company and the formula used to make its soft drink.

    He also declined to say whether the new formula Coca-Cola introduced in 1985 contained a coca derivative, noting that it was company policy not to discuss its product formulas. The Coca Eradication Plan

    American officials said recently that, as part of the Administration's war on drugs, they planned to begin testing a coca eradication program in Peru within 90 days. The testing, which is contingent on final approval by the Peruvian Government, would involve the aerial spraying of powerful herbicides.

    Critics of the herbicide project charge that it is politically motivated - an attempt to convey an impression of bold action in an election year - and environmentally hazardous.

    Others argue that it is bound to fail. According to estimates based on D.E.A. data, enough coca to satisfy the United States demand for cocaine can be produced on 96 square miles of land - an area smaller than the borough of Queens. The climates of much of Latin America as well as Africa and Asia are suitable for the cultivation of coca, a hardy, woody shrub. How the Coca Is Acquired

    John O'Brien, manager of Stepan's Maywood plant, said the company purchases coca from a Peruvian Government corporation, Empresa Nacional de la Coca.

    Employees of that company buy the coca from peasant growers, said Timothy Plowman, associate curator of the department of botany at the Field Museum of Natural History in Chicago.

    Dr. Plowman, a botanist and taxonomist who spent years researching coca in Peru, said he had known people in that country who were responsible for buying coca for Coca-Cola and for doing agronomic research for the company. ''But it was always through intermediaries,'' he said. ''Two or three steps removed.'' Bales of coca destined for Stepan and, ultimately, for Coca-Cola are shipped to the Maywood plant through ports in New York and New Jersey, Mr. O'Brien said. Each shipment carries its own import permit, also issued by the D.E.A.

    Stepan - and before that the Maywood Company, which was purchased by Stepan in 1959 - has been engaged in coca processing ''for 50, 60 years,'' Mr. O'Brien said. All the coca flavoring ingredients extracted by Stepan are sent on to Coca-Cola to make a concentrated syrup that is used by domestic bottlers and exported to the more than 150 nation's around the world where Coca-Cola is consumed and where the soft drink's familiar red-and-white logotype is closely associated with the United States itself. A Use in Medicine

    The cocaine that Stepan derives from the plants is sold exclusively to Mallinckrodt. An official for that company who asked not to be named said, ''We purchase a crude extract and purify it further into one chemical form, cocaine hydrochloride U.S.P.''

    That product is sold to hospitals and doctors ''primarily as a local anesthetic used by eye and ear, nose and throat specialists,'' she said.

    Around the turn of the century, the Coca-Cola Company actually publicized the unusual ingredients in its soft drink. An advertisement that ran in Scientific American magazine in 1906 showed pictures of Peruvian peasants chewing narcotic coca leaves, a practice still common in that country, and of Africans gathering cola nuts, which are also used as a stimulant. Coca-Cola, the ad said, ''is the perfectly balanced combination of these valuable tonics in the form of a healthful drink.''

    The ad also quoted the Spanish conquistador Pizarro as saying that the use of coca enabled both Indians and foreigners in the high Andes ''to endure without distress physical trials which are otherwise unendurable.''

    Dr. Plowman of the Field Museum noted that the Spanish tried, for religious and cultural reasons, to eradicate the coca plantations in the 16th century. They failed, he said, and finally gave up and adopted the practice of using coca themselves. Every attempt at eradication since has been equally unsuccessful.''
     

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    #24
    Bluelighter Atlien3's Avatar
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    methylphenidate (ritalin) is the closest but from what i hear that is only when IVed............so
     

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    #25
    Bluelighter delta_9's Avatar
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    Quote Originally Posted by Coolio View Post
    It's funny, cause if you wanna get technical, coca cola still contains trace amounts of cocaine, as it's impossible to remove every single molecule of cocaine from the leaves.
     

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