Well I would like to know║ how soluble hydrocodone is in methanol (wood alcohol).
I would also like to know how soluble oxycodone is in methanol.
I would like to know because I'm doing cwe's on perc's and hydro's. I would like to end up with powder instead of liquid. I don't want to boil the water away because I'm afraid I'll damage the opiates. Iso or eth. alcohol have higher boiling temperatures than methanol.
Now.. can anyone "assimilate" wtf I'm talkin bout here ? Thanks.
Alcohols tend to be quite volatile, and will evaporate quickly enough on their own. They don't
need to be boiled for quick evaporation, although you can use a little heat to speed things up.
You can look up the solubility several places online that you can find with google, but if I recall correctly, solubility in specific alcohols is generally specified as "slightly soluble", if at all.
But Boiling the water away works just fine for oxycodone. I do not know about hydrocodone, but I expect that's probably OK too.
Of course, boiling gives the fastest results but it can also cause splatter, and must be watched closely tp avoid boiling over, or (if left too long) burning. If you prefer, below boiling temperatures can also be used for rapid evaporation. For example:
1) make a small tray out of Reynolds™ RELEASE™ "NON-STICK" heavy-duty foil
1a) check tray for watertightness by placing on sheet of newspaper, pouring water into tray, and leaving it for five minutes. If tray is watertight, discard water, otherwise discard tray.
2) Preheat pizza tray to between warm and 200F.
3) place non-stick tray on pizza tray
4) pour your oxy liquid into non-stick tray
Check it after 5 minutes. If not dry, wait another 5.
Note: If you obtained the liquid through CWE, even though the APAP is gone, there will probably also be other water-soluble excipients in your liquid. The appearance of the final result will depend upon what excipients accompanied your API (active pharmaceutical ingredient) With some, you may have a powder after evap. With others, you may have a clear transparent solid that you will have to crush. Because you used a non-stick foil, you won't have to scrape the final product off the foil. By the same token, you need to be careful when handling it. Especially near a fan or central air duct!