So recently I've become more and more aware of reports around the web that Loperamide (the active chemical in the anti-diarrhea medicine Imodium) may have potential as a recreational Opioid if taken at very high doses (50-100+ mg). Some of the best threads about this are found here on Bluelight.
It was in one of these BL Loperamide threads that I noticed a few posters (including Xorkoth who I consider a very credible individual) reported that they'd noticed that if they took a very high dose of Loperamide and then ingested Kratom a few hours later that the resulting Kratom buzz was stronger and longer lasting. Most folks upon hearing this claim would prob. instantly dismiss the idea that Loperamide could potentiate Kratom and not give it any further thought. I, however, try to be very open minded when it comes to drug experimentation and not just be so quick to write things off.
So I first tried using a high dose of Loperamide alone to see if it did in fact have any recreational Opioid effects on its own. From what I'd read online it sounded like people were usually taking at least 60-70 mg or more of Loperamide for a buzz and I'd heard Lope (my nickname for Loperamide) takes a few hours to kick in.
So one night a few weeks ago I popped 70 mg and waited. I did in fact notice a couple hours later that my body was warmer and more relaxed and my mind was more peaceful and content. The mental and physical euphoria was very subtle, nothing strong at all, however the warmth my body felt was way too significant to just be placebo. I eventually smoked a bowl of good nugg and def. noticed a more intense body and mental stone than usual. Now things def. felt opiate-like. I swallowed the remaining 26 mg of Lope and for the rest of the night I was pleasantly relaxed and upbeat and had no worries.
That first experience alone didn't make me too enthusiastic about Lope's potential. Sure, I'd had a good time and it didn't feel bunk and did give me some relaxation but to fully enjoy it I'd had to smoke nugg a few times throughout the night plus I really didn't like how expensive the Loperamide buzz was (I'd paid $12 for just 96 mg).
I did end up revisiting Lope more after all though when I discovered how much cheaper it is at Wal-Mart to buy their Equate brand Loperamide. I saw that a bottle of 48 there was only $6 or $7. And for $12 one could buy 2 bottles of 96 mg each and get a much better value. So I scooped up more Loperamide, thinking I'd now see if it synergized with Kratom as claimed.
Well, I can report it seems as if it definitely does potentiate and lengthen my Bali Kratom buzzes, although, I still readily admit maybe I just have quite the imagination and have duped myself into experiecing profound placebo effects. I've used Lope and Kratom together on 3 or 4 occasions now and consistently got the same results.
For one thing, it seems like the Kratom kicks in faster. It's a warmer, heavier body high than taking Kratom by itself. Kratom's peak seems to linger a lot longer and drop off more gradually than usual. See, usually when I eat Kratom I'm only content around 2 hours or so and start strongly craving and obsessing about wanting to redose. However, if I've preloaded on Imodium it seems like Kratom keeps me content a good 3-4 hours or more. Like last Fri. I couldn't get over that over 4 hours after my last dose of Kratom I still felt really really nicely opiated thanks to the Lope.
So if anyone wants to give this combo a try this is my advice on how to do it. Take 50-70 mg of Loperamide and wait at least 2 hours. 2 or 3 hours after ingesting your Lope eat your Kratom (making sure you haven't eaten in a few hours as food tends to make Kratom kick in slower and more weakly).
Me, how I eat Kratom is real simple. I make sure it's in a finely ground form and I dump it in a cup and add (usually) milk, Splenda and a sweet flavor of coffee creamer (like French Vanila) and stir vigorously for a while. Then I chug it like a true Kratomite. Some people bother preparing teas or doing fancy extractions but I see this as pointless. Why risk losing some of your Kratom by preparing it these ways when you can just swallow it as it is and ensure you absorb every last bit of alkaloids.
Anyone who is considering ridiculing me or telling me off just keep in mind I pointed out I'm aware Loperamide's potentiation of Kratom may just be placebo but it sure as heck doesn't feel like it and feels nice...
Oh, and sorry if I'm posting this thread in the wrong forum or something. I wasn't sure whether to post here or Simple or Advanced Drug Discussion. I thought posting in Other Drugs would give me the best responses seen by the most people who might find my information useful.