Past a certain point, increasing your dose won't even get you buzzed. At my clinic they do 10mg increases (5mg for some). Think about it, when you in thirty milligrams, adding ten mg is like adding a third of your dose, so you get pretty stoned. At forty, it's like adding 1/4th. The higher you go, the additional dosage first off becomes incrementally smaller, and past 90mg, you really don't even feel a difference. Im on 40mg now, and in the last I've been on 100+mg. I get a more euphoric effect at 40 than I ever did at dosages above 70mg, I would even venture to say I get a bit stoned for a few hours in the morning after my dosage, plus, it still holds me for 24 hours. Chasing that initial buzz though is a losing battle. It always is, but especially with Methadone.