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Thread: Phenylethylamine (PEA) experiences and safety

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    Phenylethylamine (PEA) experiences and safety 
    #1
    Bluelighter
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    I've been taking P.E.A. for the past week, dosing between 0.5 and 1g at a time. Recently I've been redosing every hour because from a single dose the effects ware off after about 30 mins, followed by a comedown lasting about 1/2 to 1 hour. The effect is very much like speed.. a comfortable, content feeling. It's just a shame it's so short lasting. I used to take it twice a day (300-500mg) with deprenyl (mao-b inhibitor) to prevent it's breakdown. The 30 min high was incredible but not worth the horrible hour long comedown, not to mention a huge rise in bp and heart rate. So now I just take PEA on it's own.

    There has been quite a lot of talk here whether or not PEA on it's own is psychoactive. It most definately is. The thing is, I don't want to develop an addiction to it, and more importantly I'm concerned about the long term effects it can have. There is very little info on the web about it, so any new light that can be shed on this will be greatly appreciated.
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    #2
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    I have never noticed any kind of recreational value in PEA. And this is even when I paired it with Deprenyl (5 mg dose). Only tried it twice, but never got much out of it.

    BTW, you do know that Deprenyl taken in doses over 10mg cause it to inhibit MAO-A as well...
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    #3
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    Hi, if you took 5mg deprenyl followed half an hour later by upwards of 200mg PEA you would surely feel the effects. Note PEA is phenylethylamine, not the amino acid phenylalanine which it has been confused with in other posts here.
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    #4
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    *bump*

    Can PEA be harmful in any way? Is it neurotoxic or harmful to the body in any way?
    Thanks
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    #5
    Bluelighter Mr Blonde's Avatar
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    I doubt there's many studies into it's neurotoxicity; MAO-B eliminates it from the brian quite quickly and so it probably hasn't been considered much as a potential drug of interest.

    Everything I've heard about PEA has been that it's useless without an MAO-B inhibitor.
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    #6
    Thc and alcohol stimulate PEA release, and there alot more recreational than PEA plus deprynl. All PEA does is realease dopamine. If you really want a good PEA like high snort some coke. I know someone who has done PEA and deprynl. He turned red and looked like he was on speed. He said he felt good and described a coke high.
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    #7
    I don't even know if that's true. I stil haven't seen an answer to whether or not it's a releaser or a DARI.
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    #8
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    Myself and others have found it active in doses of a few hundred mg (myself upwards of around 150mg), and is a LOT more potent with deprenyl. I'm using it for depression, but there is a fine line between that and getting high from it, when I also will get a comedown. So it does seem to release dopamine. Thisusername - do you have any sources for that?
    It says on the package label that it shares chemical similarities to dopamine and norepinephrine which I haven't read anywhere else. There is surprisingly little info about it on the web, perhaps because it is quite new to the market?
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    #9
    Bluelighter Mr Blonde's Avatar
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    It says on the package label that it shares chemical similarities to dopamine and norepinephrine which I haven't read anywhere else.
    Well, dopamine is a type of phenylethylamine, and norepinephrine is similar as it is created from dopamine via hydroxylase if I remember. There isn't much info on it's function as a neurotransmitter.
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    #10
    Quote Originally Posted by thisusername
    Thc and alcohol stimulate PEA release, and there alot more recreational than PEA plus deprynl. All PEA does is realease dopamine. If you really want a good PEA like high snort some coke. I know someone who has done PEA and deprynl. He turned red and looked like he was on speed. He said he felt good and described a coke high.
    THC, Alcohol, Ritalin, Opiates, amphetamines all increase phenylethylamine levels. However Phenylethylamine is only a weak very brief dopamine releaser, most of it's effects are unrelated to dopamine.
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    #11
    Quote Originally Posted by jl6er
    I have never noticed any kind of recreational value in PEA. And this is even when I paired it with Deprenyl (5 mg dose). Only tried it twice, but never got much out of it.

    BTW, you do know that Deprenyl taken in doses over 10mg cause it to inhibit MAO-A as well...
    You would need to take over 15 mg of deprenyl for more than 3 weeks to inhibit MAO-B. Straight phenylethylamine dosing requires 1-4 grams depending on the person on an empty stomach.
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    #12
    Quote Originally Posted by NeuronalPerception View Post
    You would need to take over 15 mg of deprenyl for more than 3 weeks to inhibit MAO-B. Straight phenylethylamine dosing requires 1-4 grams depending on the person on an empty stomach.
    3-4mg of oral Deprenyl (selegiline) has been shown in studies to inhibit over 80% of MAO-B irreversibly for up to two weeks, which is typically when the enzymes fully return to normal. Oral Deprenyl doses > 10mg inhibit MAO A & B.

    I've tried Phenethylamine (PEA) by itself with absolutely no effects in doses up to 1.5 grams. I also tried it with Hordenine + Beta Alanine which gave me potent but VERY short lived effects. PEA is without a doubt best taken 30-45 minutes after Deprenyl. I started Deprenyl at 5mg a day for a few days until I eventually switched to 2.5mg EOD. This seems to give me a complete inhibition of MAO-B and maintains it after a short 'loading period'.

    Also when I take PEA while on Deprenyl, the effects last quite a bit longer than the 10 min feeling I got with Hordenine + PEA. As mentioned earlier though there is a fine line between dosing. If I take about 250mg-300mg I feel a very powerful mood lift and mild euphoria and small feeling of weightlessness. But if I take more than 500mg I get a very strong, way too pronounced feeling of euphoria and body tingles which is followed by a depressing comedown with lethargy. The key is finding the right dose without taking too much.

    On a side note as far as nootropics go, taking low dose Deprenyl maintenance as I mentioned above, and adding your optimum dose of PEA along with L-Theanine is a pretty extraordinary combo once you hit your sweet spots for dosing.
    Last edited by Ziquor; 19-11-2008 at 03:09.
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    Activating P.E.A using simple Fo-Ti! 
    #13
    Wink
    I was reading this forum, and figured out a much simpler, not to mention cheaper approach to activating Phenylethylamine (P.E.A)!

    Fo-Ti capsules! A HERBAL/NATURAL MAO-B inhibitor. Any health store, even some drug stores should carry them. Very cheap too, about $10 for 100 caps!

    My first test was 4800mgs of Fo-Ti (8 x 610mg capsules) and 750mg of P.E.A (Nutraceutics RX brand, 3 X 250mg caps). FYI, I'm 6'4 and 220lbs, so you may want to lower the dose according to your weight. 45 mins in, the euphoric buzz kicks in, you can't miss it! Great combo!! And you don't need to mess around with prescription pharmaceuticals. This is definitely the safer and easier approach.

    No heart rate/bp increase detected with this combo so far, at least at the dosage above. Haven't experienced a comedown yet either. It completely demolished my hangover from the night before, so there's one solid use for it!

    You can try increasing/decreasing both the Fo-Ti, and P.E.A dosages. Play around with it to find the "magic" spot.

    Earlier, I tested P.E.A at 1500mg on it's own, with absolutely zero effects.
    Maybe in their next version the PEA manufacturer will include the FoTi in the caps as the activator

    Enjoy!
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    #14
    Bluelighter
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    What is the medicinal use of the P.E.A; brand name; otc or pharm?...I think i've seen it in some cough syrups or something ... can't remember...
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    #15
    There is no medicinal use that I'm aware of. It's marketed as a mind enhancer supplement. It's not available otc and is not prescription. It's won't do much for your cough, so I'm certain you saw something else in your cough syrup

    The only way to get it at the moment is by ordering it online, in capsules and powder. Just search google for "order Phenylethylamine" or go here http://www.americannutrition.com/sto...thylamine.html

    Enjoy
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    #16
    One more thing, stick to Nutraceutics brand. The other brands (eg, Conginitive) out there are pure garbage, don't know how they manage to mess up 1 basic molecule, but they don't do the trick...
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    #17
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    Heh I heard about someone using this to cook upmeth on totse or hippy-forums or something haha it's weird how all those chemicals are so closely related
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    #18
    Quote Originally Posted by Ziquor View Post
    3-4mg of oral Deprenyl (selegiline) has been shown in studies to inhibit over 80% of MAO-B irreversibly for up to two weeks, which is typically when the enzymes fully return to normal. Oral Deprenyl doses > 10mg inhibit MAO A & B.

    I've tried Phenethylamine (PEA) by itself with absolutely no effects in doses up to 1.5 grams. I also tried it with Hordenine + Beta Alanine which gave me potent but VERY short lived effects. PEA is without a doubt best taken 30-45 minutes after Deprenyl. I started Deprenyl at 5mg a day for a few days until I eventually switched to 2.5mg EOD. This seems to give me a complete inhibition of MAO-B and maintains it after a short 'loading period'.

    Also when I take PEA while on Deprenyl, the effects last quite a bit longer than the 10 min feeling I got with Hordenine + PEA. As mentioned earlier though there is a fine line between dosing. If I take about 250mg-300mg I feel a very powerful mood lift and mild euphoria and small feeling of weightlessness. But if I take more than 500mg I get a very strong, way too pronounced feeling of euphoria and body tingles which is followed by a depressing comedown with lethargy. The key is finding the right dose without taking too much.

    On a side note as far as nootropics go, taking low dose Deprenyl maintenance as I mentioned above, and adding your optimum dose of PEA along with L-Theanine is a pretty extraordinary combo once you hit your sweet spots for dosing.
    While blood levels of MAo-B return to normal within 2 week it takes longer for cerebral MAO-B levels to return. Since 1.5 grams tends to be the beginning dose where effects are noticed it seems your dose was too low by itself.

    Quote Originally Posted by select23 View Post
    I was reading this forum, and figured out a much simpler, not to mention cheaper approach to activating Phenylethylamine (P.E.A)!

    Fo-Ti capsules! A HERBAL/NATURAL MAO-B inhibitor. Any health store, even some drug stores should carry them. Very cheap too, about $10 for 100 caps!

    My first test was 4800mgs of Fo-Ti (8 x 610mg capsules) and 750mg of P.E.A (Nutraceutics RX brand, 3 X 250mg caps). FYI, I'm 6'4 and 220lbs, so you may want to lower the dose according to your weight. 45 mins in, the euphoric buzz kicks in, you can't miss it! Great combo!! And you don't need to mess around with prescription pharmaceuticals. This is definitely the safer and easier approach.

    No heart rate/bp increase detected with this combo so far, at least at the dosage above. Haven't experienced a comedown yet either. It completely demolished my hangover from the night before, so there's one solid use for it!

    You can try increasing/decreasing both the Fo-Ti, and P.E.A dosages. Play around with it to find the "magic" spot.

    Earlier, I tested P.E.A at 1500mg on it's own, with absolutely zero effects.
    Maybe in their next version the PEA manufacturer will include the FoTi in the caps as the activator

    Enjoy!
    Can you cite any studies on fo ti inhibiting MAO-B? Many common foods inhibit MAO-B potently.

    Quote Originally Posted by select23 View Post
    One more thing, stick to Nutraceutics brand. The other brands (eg, Conginitive) out there are pure garbage, don't know how they manage to mess up 1 basic molecule, but they don't do the trick...
    Considering most companies are buying from the same source there is no quality difference.
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    #19
    Bluelighter drug_FUCKED's Avatar
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    i got enough effect just mixing it with a few other nootropics and smart drugs and l-theanine.
    Will be trying PEA combo again soon. Its certainly not going to be a street drug or legal high cause u need too much. I also think having over 5mg of deprenyl should be done carefully and read as much info as you can. Its a serious thing to mess around with MAO's. and over 5mg i have had issues with the HCl version. citrate one was always better the one from mexico.
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    #20
    .I just tried this stupid as PEA shit, and it sucks.. i took 1.5 grams and omg this is not a good feeling at all.. Its not bad = but it no where neear fun...

    5mins later...well im glad that shits over with lol (i made a few spelling mistakes too... weird)( BP feels high as hell too!)
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    #21
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    Having done both PEA and coke, I can say they're nothing alike. PEA is much more body, coke is much more head. If you're doing PEA and thinking you're getting an experience like cocaine you're retarded. It's closer to mephedrone, I'd say.

    The best way to potentiate PEA is with 200 mg caffeine 15 minutes before dosing. I liked 200/1750. Redosing usually only required 500-750 mg but since the comeup takes as long as the peak you'll want to redose as soon as you feel the peak (which is scary but works).
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    #22
    Hi.

    I agree that alone, PEA is very much a body high.

    But after a few days of 5mg deprenyl, then the body effects are supressed by the deprenyl and the high is very euphoric and mind/head.

    the deprenyl does not make the dosage required too less or extend the duration too much...

    but its really nice, except for horrible nausea & puking.

    if i could find a way to get rid of the nausea then it would be nicer than mephedrone.

    one more thing....
    smoking caapi actives (MAO-A inhibitor) made the euphoria even more & also the duration even longer.

    just a shame it messes up your gut.


    if there were a way to get the side effects of this stuff down, without having to transform it into speed then that would be awesome.
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    #23
    I usually pre-load with Deprenyl, taking 7.5mg for a week and then back to 2.5mg/day. It greatly enhances the effects of PEA but I don't lower the dose....still take 2 grams spread out through the day.
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    #24
    Is it safe to take rhodilia rosea with PEA? I was told it was just a mao-B inhibitor, I took 400mg with 100mg PEA, and now I found out it is MAO_A?B inhibitor. Shit should I be worried?
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    my experiences with PEA/selegiline 
    #25
    Greenlighter
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    started taking 2.5 mg selegiline every other day for mood lift/energy (which has indeed been helpful). after about 1 week, my PEA came in the mail (couldnt find it at stores) as 500mg caps (prima force). in the am, took 2.5mg selegiline sublingualy (i dont recommend this b/c it leaves an acidic aftertaste the whole day) to increase bioavailability and then about 20 min later opened up a PEA cap and took about 1/2 of the 500mg in water. not much of a feeling from that so i doubled the PEA the next am to 500mg. felt a tad more but nothing to write home about. next am i took 1g PEA and was off to the races with mdma wavey type body/head feeling but this lasts for only 20 min or so and head feels hypertensive (as well as gut not being too thrilled). on all mornings, i also had my usual double cappuccino.

    got to the office on that 3rd am and about 3 hours from the first PEA dose took another 1G with some chocolate. was quite stimulating and made me feel frisky/horney with body/head waves (which are noticed more the less u move). was quite extroverted and had a biz meeting in which i was funny and smart. but, the feeling only lasts 20-30 min.

    later in the day, took another 1G PEA before my usual thai massage. because of the movement of the massage, the effect was less pronounced; however, the feeling of the massage was heightened and exponentially more enjoyable.

    later that night, had to take 600mg ibupropin to deal with hypertensive head and felt generally unwell.

    while some of the aforementioned was enjoyable, the addictive redosing and side effects of PEA are unnacceptable/unpracticable.
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