Ok, I thought I would mention one thing that is extremely important in evaluating the subjective effects people on this thread seem to be ascribing to soma in their personal accounts of their use of it - this is one that I have seen no talk of. Soma's main metabolite in the liver is meprobamate (the old and very potent sedative known as Miltown, now replaced in modern medecine mostly by benzodiazepines and z-drugs (zolpidem, zolicone, etc; much as have barbs). Soma actually started as a modification of meprobamate but it wasn't realized until some time later exactly how much meprobamate soma is actually metabolized into. Carisoprodol's effect can also vary based on the patient's exposure to CYP2C19 inhibitors which include prescription drugs but certain herbal supplements and also more normal foods especially juices than one would think. Intake of this results in increased exposure of carisoprodol and decreased exposure of meprobamate. ALSO, exposure of carisoprodol is higher in female than in male subjects. AND, whoever it was saying their Soma tolerance is so high, this is likely because it is only designed for short term exposures at a time (such as 2-4 weeks). A list (non-comprehensive) of drugs Carisoprodol has serious chemical reactions with (when taken together): diphemhydramime, alprazolam (xanax), diazepam (valium), zolpidem (ambien - this is a very damgerous combination - please do not take), and of course meprobamate. It also reacts with all opiates as many have noted, but SPECIFICALLY strongly with those of the codine, codone (Oxy, Hydro), etc class; also any opiate that begins with the raw material from the poppy Thebaine (paramorphine - aka codeine methyl enol ether). Just wanted to add this - some may be repetitive, and if so, I truly am sorry.