johanneschimpo said:
Well fetuses have undeveloped BBBs - maybe everyone who gets high off it is a fetus or has some sort of faulty BBB.
Maybe malfunkshun's mother took plenty of loperamide during pregnancy, causing fetus-malfunkshun's underdeveloped BBB to become accustomed to loperamide, leading to his ability to get high off of it later in life.(complete and total drugged out speculation, with absolutely no basis in reality)
On a side note, taking 100 loperamide pills isnt quite as hard as it seems. When I take lope for withdrawal I usually take about 5 of them, but I have a very hard time swallowing pills, even those extremely tiny 2mg loperamides. So I take my 5 pills and break them in half and put the halves into a 00 size capsule and take them all at once. Using this method you would only have to swallow 20 pills in order to take 100.
If you were to crush 100 of them and fill up some capsules it would be much less than 20. Maybe taking such a huge dose at once floods your BBB with the drug and small amounts sneak by and get you high. It was afterall designed to be a very powerful pain killer, but since it cannot readily cross the BBB it was downgraded to a constipation medicine. If even less than 1% of a 100mg dose somehow crosses the BBB it may just be potent enough to actually get you high.(also all complete speculation, with no scientific basis to back up these theories)
Loperamide does work well for WD, I have used it many times and it really does help. Maybe by taking huge doses of it during the height of opiate WDs the feeling of no longer WDing along with the loperamide binding to the opiate receptors throughout the rest of your body(not just the ones in your brain) it might cause some sort of euphoria(or maybe the euphoria is only a mental state caused by no longer feeling like shit from the WDs)
Either way, if it works for malfunkshun more power to him. Everyone else is just jealous that they can't get high from a drug that is cheap and readily available anywhere.