The anti-depressant/MAOI FAQ on this site claims that opiates are contradicted with MAOIs.Opiates (Heroin, Codeine, Vicodin, Oxy etc): It is NOT SAFE to use opiates while on a MAOI. Combining these drugs could lead to hyper or hypotensive crises, as well as respiratory complications. Avoid these drugs if you are taking a MAOI, PLEASE!
Can somebody please explain the mechanism underlying this? I tried searching on google scholar and all I came up with is that MAOIs can potentiate opiates and also another article stating that the combo could result in a hypertensive crisis.
Thanks, to be informed is to be armed,