There is nothing better on the planet than being alone w/ a member of the opposite sex you love (no need for true "bf/gf", just someone meaningful to you), both dropping a ton of MDMA (easily half a gram through the night) and several blotters apiece (enough to enhance, w/o getting too trippy). Add enough lotions/toys, lock the doors/tape the windows, and NOTHING can compete with that. I've hit over 8hrs ;P
Also taking tons of shrooms and/or acid w/ a small-enough group of good friends, hiding the car keys, and just going out in the city. Going to the woods is a close 2nd to that ;P
For practical life, nothing beats some good amp's when you have a house to clean, hard homework, or boring tasks!!!