I tried that years ago, and it was a really messed up experience. I literally swallowed a handful of Dramamine and proceeded to have all kinds of hallucinations, but not until I'd found myself really creeped out for no particular reason. I tried to relax, but then I had the most intense urge to piss. I got up, sat on the toilet and peed for what seemed like ever until the concurrent projectile vomiting started. It was so violent that I could not catch my breath, and with my pants around my ankles and still peeing the hottest piss (temp-wise) I've ever pissed, I pitched forward onto the hallway floor of this little RV I'd been staying in. There I lay, in a an ever-widening pool of pee, choking on my own puke, thinking about how I'd be found dead in this embarrassing position days later. Next thing I know, I'm laying in complete darkness (whereas before the TV monitor and a couple other lights had been on when I'd first got up to pee) and my pants are off but I'm wrapped in a warm blanket on the bed in the bedroom. I don't feel right, so I turn on the light and look in the mirror and my eyes were completely bugged out of my eye sockets. Just like someone with a bad case of Graves disease. I looked so freaky I scared myself! (Much later I learned that was caused by intercranial swelling.) I avoided answering the door until about 2 or 3 days passed and one very insistent friend of mine banged on the doors and windows to make sure I was okay. I was shook for days, shit maybe even weeks, after.
This all started because I was bored and in search of a new high. I'd heard you could trip on it, which is why I tried it, but I'm pretty confident I nearly died )or maybe I actually did die) & I'll never know how I got from the floor in the hallway into the bed...Yeah: I highly recommend this medicine only be taken as per the directions on the bottle if at all. It was a horrible experience.