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new suboxone pill

^yea same here. bupe gives me a bad headache sometimes. i get migraines but its not the same. its just like a dull throbbing headache....it sucks. ibuprofin works pretty well for stop it, but i worry about taking that stuff all the time.

i wanted to get on subutex but my dr wouldnt go for it...i think she thinks i want it so i can blast it.
 
Hmm both addiction specialists I've been to were weary of giving just subutex, the 1st one started me with 5 pills of subutex then only suboxone after that.

Its funny you mention new suboxone I thought you were talking about this new generic suboxone I just started getting, its a little cheaper than the reguler one but it comes in 4 dose 32 mg / 8 mg squares divided into 4 peices, its like wax which is weird, but its grape flavored which is awesome cause I HATED the taste of regular suboxone tablets. Its strange cause until I found out about these pill I thought that suboxone was higly regulated and there was only 1 kind no generic equivlent. I'll check the company name when I have time.. these are the shit tho, still a little funky tasting but not overbearing.
 
makaveli777 said:
Thats interesting... I get headaches On doses of suboxone above 4MG... i'm going

to bring this up to my doctor and possibly get the subutex script instead. I never

was an IV user so i Shouldnt have any problems right?


If you are in the US it is highly unlikely you will get scripted subutex.
 
I got prescibed subutex living in FL. I was in outpatient detox and my doc never even brought up suboxone.
 
Yeah I live outside Chicago, the subutex was a 1 time thing, like so I didn't get sick the 1st 5 days. The guy I'm seeing now is closer and not as strict but he just started me right onto the suboxone, I had to come to the 1st visit already sick and he started with a suboxone right there on the 1st visit. Its by a company called Troche. Really weird substance, made of wax that is easy to break up into doses. I think it resembles methadone tablets that are squares you divide into quarters.
 
diacetyldeath said:
The holy grail would be a selective, full mu1 agonist (no activity at mu2), antagonist at delta (like buprenorphine), full gamma agonist. I am both curious and very scared to see what will happen to the opiophobic/"narcotics are evil" propogandized community when selective-mu agonists can be created. Since both respiratory depression and tolerance are functions of mu2 and delta, this would be an opioid with a virtually unlimited dose ceiling, no potential for (fatal) overdose, and limited/no physical addiction.

It is possible to prevent the onset of tolerance for the most part already. Do some research on CCK antagonists (Proglumide et al), NMDA antagonists' effects on opioid potentiation and attenuation/prevention of tolerance, and ultra low-dose antagonist (e.g. naloxone) effects on opioid potentiation and attenuation/prevention of tolerance. I have used the CCK antagonist and ULD Naloxone routes to successfully block/somewhat successfully attenuate tolerance (to a point) in the past, and had I known their capabilities, would have killed to have these substances around at the beginning of my opioid "experiences."

Anyway, with enough knowledge and proper application of the above strategies in combination with not going too crazy on dose escalation (it sounds like you are already adequately paranoid/prepared on that subject), it would be substantially easier to maintain a full agonist "habit" with little to no dose escalation in the long-term.

Just some interesting subjects to read about if you haven't already.

-DD


Gamma opiate recpetor types? Where is this proved? or even mentioned
 
johanneschimpo said:
A quick googling brings us:

1. A tertiary nitrogen with a small alkyl substituent.
2. A quaternary carbon.
3. A phenyl group or its isosteric equivalent directly
attached to the quaternary carbon.
4. A 2 carbon spacer between the quaternary carbon
and the tertiary nitrogen

This is referring to the opiate's molecular structure.

Looking at bupe, it looks like it actually does follow all parts, as it should being morphine-derived.

The reason bupe lacks the euphoria of a other opioids, such as heroin and oxycodone (pure agonists), is simple; buprenorphine is only a partial agonist at the mu receptor.


Sorry for the hijack.
bupe is thebaine derived
 
jasoncrest said:
Whoah! A Buprenorphine implant?! That's interesting!

Here's a bit of information: http://www.titanpharm.com/pdf/CPDD.pdf

This implant is called "Probuphine".

I wonder how many mgs of Buprenoprhine it delivers in a day?
The implant works for 6 months.
It delivers the drug 'intrathecal' Or, at the base of your spine. This means you only have to administer like 1/100 of the IV dose.
 
this will probably get closed but,

on the 28th i am set to take part in a research study here in baltimore for a new type of suboxone pill. it is supposed to be like one of those rapid dissolve type pills. i hear its supposed to be a new flavor as well. the formulation will be the same but the pill will be different size/taste ect..

the study wont give me an actual dose of the new pill, its just a marketing group to try out the new pill and how fast it dissolves, then i guess i rate the pill on taste and how fast it breaks down. which is weird cause you think reckitt becksindale or however you spell the manufacturers name would be interested in if the buperenorphine gets absorbed any faster.

if anyone in the baltimore area takes suboxone and is interseted in the study PM me. it pays 50$ for 30 mins also.

This is from awhile ago, so I'm interested if you completed the study and how it went. I can't PM yet as I'm not yet a "bluelighter", but PM me if you would about it.

Thanks
 
The holy grail would be a selective, full mu1 agonist (no activity at mu2), antagonist at delta (like buprenorphine), full gamma agonist. I am both curious and very scared to see what will happen to the opiophobic/"narcotics are evil" propogandized community when selective-mu agonists can be created. Since both respiratory depression and tolerance are functions of mu2 and delta, this would be an opioid with a virtually unlimited dose ceiling, no potential for (fatal) overdose, and limited/no physical addiction.

This gives me friggen wood! lol... where the F--- do I get this?!?!?!?!?!?
 
Ahh, seems like they finally listened to the people sick of the lemon-lime puke tastes.

I wished this was news of a new generic form of suboxone hitting the market. Meh, this will happen fairly soon I suspect.
 
Ahh, seems like they finally listened to the people sick of the lemon-lime puke tastes.

I wished this was news of a new generic form of suboxone hitting the market. Meh, this will happen fairly soon I suspect.


Well generic form of the current suboxone would be great too... then we wouldn't be paying $5 a fricken pill.....:p
 
^^^^^^^
that has to be some of the funniest most ridiculous shit ive read all day, full gamma agonist lol
 
I can understand why they would want a faster dissolving subutx/suboxone pill - it would help stop diversion. I know a lot of people who manage to put their pills under their tounge, and manage to get them out minutes later - pretty much intact.

I would be happy with *any* flavouring put in my Subutex tablets. Over here they are bitter as fuck, its like putting 3 paracetamol under your tounge for breakfast. TBH though, its a small price to pay for being clean..
 
The type of diversion you mention isn't as prevalent in the US (I can't speak for any other countries). Suboxone is given out in prescriptions, not at clinics, although there are clinics similar to Methadone clinics where they give out Suboxone instead, but the good majority of Suboxone patients have take home prescriptions.
 
You don't get that anywhere, because that guy has no clue what he is talking about, and some of the shit he is talking about doesn't exist.
"oooh a full gamma agonist...." 8)
LMAO.. I was kidding I know that it doesn't exist but who here doesn't WANT it to right?
 
LMAO.. I was kidding I know that it doesn't exist but who here doesn't WANT it to right?

Yea dude, have you heard of gamma rays? If you ever get the chance, make sure you get your hands on some of them. I've never been so high in my life.
 
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