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Thread: Opana - be cautious!!!

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    Quote Originally Posted by hatedenial
    Opana is "out there" it's made a jump in availability in the midwest in the last 4 weeks. VERY , VERY powerful opiate! If you like the Oxy high, then you may not like the Opana, if you like the Dilaudid high, you will like it. The 10mg ir's are the best way to go. BE VERY CAREFUL THOUGH! I have an Oxy tolerance of about 300 to 500 in a 12 to 14 hour period . I can only tolerate about 80mg of opana in that same time period. Oral route is not good(Low BA) IV and Snorting is best, but be very careful or you'll wake up dead. Good Luck.

    Kinda hard to wake up when your dead, i guess.
     

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    I have been scripted opana er 20mg for the past couple months, and I have to say that i really like them. I don't get high off of oxy anymore, so i snort my opanas first, then save the oxy for when i run out. I'll usually snort one in the morning, at lunch, and before i go to work. the high lasts a good 4-5 hours, and i find that i don't crave oxys when i'm on them. only downside is that they are pretty expensive even with my health insurance. and tolerance builds pretty fast.
     

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    ^^ and not to mention, addiction...
     

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    I find the Opana ER 40mg the best of the bunch to snort, even better than the 10mg IR, which is the best to shoot.

    With a 40mg ER, I wipe the coating off, break it into 1/4's, and then smash one of the 1/4's up really well with a card. After it's all smashed, I got at it with a super-sharp razor/knife. You need it to be as fine of a powder as possible. Then, I make two lines out of it and snort, one line per nostril. It doesn't "gel up" so much as turn to a paste, and as long as you don't inhale like a freakin' hurricane, you won't get a drip. This is good, I've found. If you crush/cut well enough, it feels like 60-70% is released in the first 10 minutes of snorting, but the gel/paste that's in your nose will still work in somewhat of a time-release fashion. Snorting the ER, I get an intense high that lasts up to 8 hours. Snorting the IR gets me a high that lasts 4.

    The info about taking it after a fatty meal is absolutely true, and I would say it increases BA by at least 30-40% across the board (as in, for all MOA's). 10mg insufflated an hour after a fatty meal feels equipotent to about 60mg of OxyContin snorted. Opana is the ONLY opiate I can catch a nod off of snorting anymore; OxyContin, Dilaudid, Heroin... None of them do it to me, but Opana I can count on again and again.
    My friend (slightly opiate tolerant) was throwing up, but incredibly high, off of just 4-5mg insufflated. He usually does 30-40mg OxyContin or 8-12mg Dilaudid to get a buzz.

    When using IV, I use the 10mg Opana IR's. 10mg IV is about the same "feeling-wise" as 180-220mg oral Oxycodone. It's very, very strong. The same friend mentioned above did 1-2mg IV and was nodding harder than I've ever seen. He was never in any danger, as his respiration never suffered/dropped, but he said the rush was better than sex. I can say that yes, yes it is. I've IV'd the stuff probably 200ish times, and never once been disappointed. Dilaudid has grown old, morphine has too many side-effects for the dose I need, and Oxycodone is alright but I have trouble nodding (and it's too damn expensive) not to mention the lack of any kind of "rush" when IV'd.

    If people are thinking that Opana is over-rated or sucks or whatever, that's fine with me. It will at least keep it out of the news (unlike OC, which is the media's demon-child Rx drug), and keep prices down on the street. I really do see Opana becoming the next OxyContin, and it will start happening within the next couple of years while it is still available only in brand-name formulation. Endo Labs (the mfgr) has a lot of money to be made off this narcotic, and Rx's are already increasing rapidly. It's the only pharmaceutical that, IMO, is worth more than $1/mg on the street. I can't believe how much people pay for OC's and shit when this is so much stronger.
     

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    I take 40mg Opana ER in a.m., 20mg Opana ER at noon, 40mg Opana Er at night and 5 mg Opana Ir 4 times a day for breakthrough. I've taken just about all opiates available for pain and Opana ER is the most powerful analgesic I've ever taken, especially when taken on full stomache of fatty foods.

    I used to take 320mg Oxycontin throughout the day and was satisfied with the analgesic effect until the change to Opana. Will never go back to Oxycontin.
     

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    Bluelighter svacheme3's Avatar
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    There's some weird cross tolerance issues with oxycodone and Opana. I have a massive oc habit, ~800mg average, 400-1600mg range depending on time of month, and I am essentially unable to get high from Opana. I've done up to 120mg IV from the 10mg IRs (i.e. it wasn't tied up in gel), and wasn't even close to nodding.
    I had to be off oxycodone and doing nothing but Opana for 5 days before I could even feel anything after the rush. After that I started seeing how good the stuff was. I guess it relates to that small percentage of oxycodone that's metabolized into oc in the body. I had the doc giving it to me discontinue it and give me more oc instead, not worth it.
     

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    Svacheme3: I'm not calling you a liar, but I find it incredibly hard to believe that you could "feel" 120mg Opana IV. I don't know how you even managed to IV that much at once; that's 12 pills. I can't fit more than 3.5 (MAYBE 4, but that is REALLY pushing it) in a large spoon. There must have been something done wrong that either destroyed the oxymorphone (i.e. using a lot of heat, which is very, very bad) or prevented it's absorption (i.e. trying to fit 12 pills in one spoon).

    According to a narcotic dosage converter (with 0% cross tolerance entered), 120mg IV Oxymorphone is = 2400mg oral/insufflated oxycodone or 2080mg IV oxycodone (high oral BA). I went on a five-month binge of multiple daily shots (3-6 shots/day) and at my peak was doing no more than 40mg oxymorphone IV (well, I was also doing 10-30mg Hydromorphone IV, 60-300mg Morphine IV, 30-200mg Oxycodone oral/insufflated (don't IV OC b/c no rush), wearing up to 3x100mcg/hr Duragesic (Fentanyl) Patches, 2x1600mcg Actiq (Fentanyl) lozenges, 50-300mg Meperidine, 40-140mg Hydrocodone, and up to 600mg Codeine; obviously not all in one day, but usually 3-4 of these PLUS the 35-40mg IV Opana IR). Insufflated, and using the 40mg Opana ER, I could do 120mg/day and stay nice and high (like other -morphones, Opana produces a qualitatively different high depending on MOA) but not be nodding, like you describe. Any more than 30mg IV in a 6 hour period and I'll be nodding my ass off. The only thing I can think of is that there is something in your body making the Opana not work right... Your effects are the EXACT OPPOSITE of what I've observed in every other person I've seen do it (probably ~12-15 people). Opiate-naive people tend to be beyond high at 2-3mg insufflated or .7-1.2mg IV, and even people that are decently tolerant to opiates (will snort 80-120mg OxyContin or 16-22mg Dilaudid for a decent high) will get floored off of 5mg Opana IR insufflated, or 3mg IV (the specific person who did that IV dosage, even with 25mg Promethazine and 25mg Diphenhydramine administered via IM injection 30 minutes prior to the Opana injection, threw up multiple times and was nodding hard enough that I had to stay at their house for 5 hours to "babysit" them and keep them from OD'ing; or at least be able to call an ambulance if, God forbid, they DID OD).

    You have an extremely unusual scenario. If I were you, I'd look at the Opana IR IV-use preps in the "Opana Mega-Thread", and see if you did anything even similar. Preparation of this drug for IV makes a big difference, I've found. Doing it wrong could be the difference between getting 5 of the 10mg in your spoon or getting 9.998 of the 10mg in your spoon. It's easy to screw up (watched my friend mess up a whole 10mg pill yesterday trying to learn how to IV these himself without ever having watched me do it closely; I died a little on the inside), and prepping them is different than prepping any other pill I've come across.
     

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    someone help me out....please! 
    I get prescribed 80mg of ocs 3x's a day..I've never even HEARD of Opana, let alone done it......I live in the US, so i guess its available over here...i need stronger pain relief, but my doc is cool...but he's not a pain specialist....all the P.S.'s ive been to are assholes, and i end up either doing heroin & cocaine and get dropped by them, or i have to leave them cuz i signed a contract wouldnt dr. shop....is Opana stronger than 80's? i was gonna ask my doc for 160 mg oc's (i live in a med controlled house) so he probably would give me those,but he told me that they don't make an oral form of dilauded, and i know they do..i've had it.....should ib switch dr.'s again? get the fent. pops?? i know they are strong and work....but opana i've never heard of..thanx,

    g.l.p.
     

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    Bluelighter svacheme3's Avatar
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    Never put more than 2x10mg pills into a 1cc shot; I get to the larger amounts by doing many shots over an hour or so (as with oc b/c of solubility limits). No matter how it's prepared, no heat, some heat, or lots of heat, the end result is the same. Not much variation in preparing the IRs besides heating time. There might be something wrong with me preventing it from working; but all other opiates work perfectly. It's gotta be cross-tolerance, isn't metabolism into om ~10-15%? That means an 800mg average dose would lead to an average tolerance to 80-90mg of om to begin with. But still, I was disappointed. Once upon a time, before my usage was in the stratosphere, I had pure oxymorphone, and the high from a couple crystals placed on my tongue rocked my world.
    The mega-thread IV posts seem to concern only the ERs, did I miss something?
     

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    Thumbs up
    Quote Originally Posted by cjd83us
    just give up on this drug. it was designed very well and is way harder to abuse than oxy's so just stick to those for now. and opana er's DO gel up it takes about 10-15 mins then i feel it in the back of my throat and can cough it up. it is really quite nasty however i do enjoy this drug since it is so much cheaper to me than others it really is just a pain in the ass
    You just have to know how to get the gel out if you want to snort it. I just snorted a 20mg and it is already kicking in! What you do is this...first off, if you don't have one of those pill crushers (the one that you unscrew, put the pill in the little cup, then screw it back on), then buy one. They work the best. Then, either put the pill in your mouth to wash the coating off or put it in a cup of hot water for about ten seconds. Then, make sure you rub all the coating off if the water did not do it for you. Then, put the pill under a hairdryer on the low setting so that the pill won't fly away from you. That will make it very dry. Then, put it in the pill crusher and crush it. If the crusher did not crush it up into fine powder, then use something small and flat (I use a lipstick lid) and crush it up better. Then, you will probably see little white flakes in the powder. This is the gel strips. Try to take out as many of these gel strips as you possibly can. Then, you are ready to snort! It sounds complicated, but you will get the hang of it very quickly, and it is worth it, trust me!
     

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    Quote Originally Posted by Mad Dash
    i can do an 80 and barely nod yet 15 mg of this up the nose will have me nodding harder than H. i just got through a night of babysitting someone who just about OD'd on ~3-5 mg. VERY POWERFUL. i can not stress enough how strong this stuff is, if you are gonna bump it use even less!! and shoot it... well, i just hope u have an insane tolerance.
    I strongly disagree with the 1.5 year old thread...
     

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    Bluelighter Foul Play's Avatar
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    Opana is one of the strongest opioids most drug users are going to see in their lifetime. I used to have a huge habit. 3 grams of tar a day. And seriously, 20mg's would have me burning holes in my shirt ! The only thing I didn't like (compared to dope anyway) is the high seemed very short lived. it only lasted an hour, maybe two at most, for me anyways.
     

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    i have also heard form multiple sources oxy/hydromorphone are more intense but much shorter lasting than the codone counterparts.
     

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    Quote Originally Posted by wazawaisuru
    20 mg of Opana insufflated makes me barf like a motherfucker. And the drip is nasty--like saccharine on steroids. I think it's because I snort the coating, which has a sweet taste to it.
    I totally agree with you! When I snorted it for the first time, my mind automaticlly thought, "stale Freetos!!" It was nasty! And I lick the coating off too. Everysince, it always tastes the same to me..stale Freetos! It is the nastyest pill that I have ever had up my nose, but I can get through the taste and smell of it because it works so darn good!
     

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    Quote Originally Posted by GETYAGUN!!11
    i have also heard form multiple sources oxy/hydromorphone are more intense but much shorter lasting than the codone counterparts.
    I don't agree with that. Before I found Opana, I snorted Oxycontin and Roxycodone which only lasted at the max 2 hours. But the Opana lasts me a good 4 hours! Maybe everybody's metabolism works quicker than others when it comes to how long medication lasts.
     

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    Bluelighter Mad Dash's Avatar
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    lol funny to see this thread back up.
     

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    ^ Ya, it is, isn't it?

    Anyway, I've been Rx'd 2x Opana ER 20mg a day for chronic pain, and while I mostly insufflate them, they are by far the strongest analgesic I've used. I was switched to this from 4x OxyContin 20mg a day. HUGE jump in potency!

    However, in the last 6-7 days, my tolerance has gone from 50mg of oxycodone for a good high (I worked hard at getting my tolerance down! I had been up to 60-70mg IV Opana a day!) to, at least for oxycodone, needing at least 200-250mg to catch a nod. Keep in mind, this is SIX or SEVEN DAYS WITH 40MG OF OPANA PER DAY!!!

    This stuff WILL destroy your tolerance to any and all opiates! I lost 50% of the euphoric effects of snorting it within 4 days (I refuse to up my dose; I get the med from a pain doc, and as the analgesia has only gone down 20%, I'm not going to snort it AND escalate my dose constantly!), and will be taking an every-other-day break here soon. I have a bottle of "Norco 10/325mg" that will let me stain pain and w/d free while I go on "no-Opana" mode for a day or two and see what that does.

    OF NOTE: I have been taking Hydrocodone as a (non-prescribed) breakthrough pain med, as my doctor won't give me anything for BTP (I can't complain; I'm 20yo and he scripts me Opana. Before you get in a huff, it's for legitimate, debilitating pain) due to the fact that I purposefully chose a clinic that is less medication-focused and more interventional-therapy focused.
    So, I have a bottle of Hydrocodone/APAP 5/500 that I'm using for breakthrough pain, that was amazingly left over from a surgery I had 2 years ago. I couldn't BELIEVE there were ANY opiates in my household, other than my current Rx!
    Anyway, hydrocodone works FAR better than oxycodone does in this situation, and I'm thinking it's because of the metabolites. Hydrocodone is metabolized partially into hydromorphone, while oxycodone is metabolized partially into oxymorphone. Thus, by taking Oxycodone, I would just be adding more opiates that compete for the same-exact-receptors. With hydrocodone, however, there has to be some incomplete cross tolerance (as all opiates work the receptors SLIGHTLY differently...), because 10mg Hydrocodone is FAR more effective for pain (on top of 20mg Oxymorphone) than is 10mg Oxycodone. This is unusual, as 15mg Hydro = 10mg Oxy, but for me it is now more like 10mg Hydro = 12.5-15mg Oxy.
    I know we're not all chemists or anything, but does my above theory sound reasonable?
    I tested it in another way: I took my Opana, and for BTP used 100mg Tramadol. Yes, tramadol. Believe it or not, the 100mg broke through the Opana and seemed to have 90% of the effect it would on it's own, additive. Perhaps it's because tramadol isn't a real opiate, but it sure increased the effects notably.
     

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    Quote Originally Posted by Butterflyluver31
    I don't agree with that. Before I found Opana, I snorted Oxycontin and Roxycodone which only lasted at the max 2 hours. But the Opana lasts me a good 4 hours! Maybe everybody's metabolism works quicker than others when it comes to how long medication lasts.

    Yes, that is RIGHT ON THE MONEY!

    Insufflated, Opana ER lasts 4 hours, almost to the dot. Oxycodone, when insufflated, doesn't last longer than 1.5-2 hours, and trails off, as opposed to Opana that gives you a FULL HIGH for 4 hours then trails off for about 10 minutes and then... time to redose!

    Same is true for IV use. Oxycodone barely lasts 1.5-2 hours when injected. Opana IR, used IV, has a good 45-60sec rush, followed by an intense high lasting 1-1.75hrs, and then has a high that's less sedating, more "speedy, that lasts another 1.5-2 hours. Then it's time to re-dose again.

    The only -morphone that is "weaksauce" when it comes to how long it lasts would be Dilaudid. Even taken orally, what little effects you DO get don't last longer than 4 hours. IV, you get a 30-45sec rush, followed by a 10 minute high. Then it's gone. Insufflated, you're lucky to be high for an hour. IMO, it's only good in extremely large shots (24mg+), taken with a TON of potentiators/enzyme-inhibitors, or used in a PCA-unit (patient-controlled analgesia pain pump) which, unfortunately, we don't get to bring home from the hospital as souvenirs.
     

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    I agree I od and died for 17 sec. on a oral 40mg and about the same snorted
     

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    Quote Originally Posted by Mad Dash
    i can do an 80 and barely nod yet 15 mg of this up the nose will have me nodding harder than H. i just got through a night of babysitting someone who just about OD'd on ~3-5 mg. VERY POWERFUL. i can not stress enough how strong this stuff is, if you are gonna bump it use even less!! and shoot it... well, i just hope u have an insane tolerance.
    According to the average strength, opana is 3x as strong as oxycodone. I have taken I50mg of opana ir, and 800mcg of fentora, IMO the fentora 200mcg is = to 200mcg of Fentora. If opana is too much for you, don't touch fentora or actiq.
     

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    Bluelighter
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    Quote Originally Posted by Butterflyluver31

    Originally Posted by GETYAGUN!!11
    i have also heard form multiple sources oxy/hydromorphone are more intense but much shorter lasting than the codone counterparts.

    I don't agree with that. Before I found Opana, I snorted Oxycontin and Roxycodone which only lasted at the max 2 hours. But the Opana lasts me a good 4 hours! Maybe everybody's metabolism works quicker than others when it comes to how long medication lasts.
    I do agree with that. Well, i dont have as much experience with opana to be honest but dilaudid only lasts half as long as oxy or hydro for me, maybe shorter. Ive also found that it deffinitly doesn't totally cover up my oxy craving and if its all i got its really fuckin frustrating. Oxy gives me 4 hours, opana 3, dilaudid 2. peace [be safe!] -Spaz-
     

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    Bluelighter ohline's Avatar
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    if you could crush jesus up and insufflate him, he would be called oxymorphone.
     

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    wat
     

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    Papasomni ftw.
     

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    trust me as a former lover of the OC 80's who quit those once RX'd Opana ER 10's for therapeutic use (yes. not even analgesia ), Opana is incredibly strong. Some people that get the ER's might not be getting the coating (time release) off correctly, to be honest, scraping it off is all but impossible, the pill is too cakey and will come apart if you try to do that. I would say 14x is a bit of an exaggeration, but 4x stronger than oxy would be about right. I've never IV'd it, and my tolerance has shot through the roof, but I don't IV anything as a personal policy.

    In conclusion imho:

    OC 80's> Opana 10 ER (with coating removed) or Opana 10 IR
    Opana 10 ER (with coating removed)> OC 40's

    Note on the second: Opana is much more Euphoric than OC is, I'd say its a safe bet the analgesia is identical.
     

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