I would love to hear more about the 40mg experience before I try a second higher trial tomorrow. I'm especially curious as to whether there was any physical discomfort as 8-12mg felt VERY safe on the body. I would imagine that since DMT/5-MeO-DMT are endogenous, the body knows how to handle DMT fairly well regardless of what else may be attached (psilacetin, psilocin, psilocybin).
My plan is to take around 16mg or so mixed with OJ and ingested over 30 minutes. I don't expect the OJ to have any effect, its mainly for taste and to smooth the come up. I will be sure to report back, but I imagine compared to the 30mg I.V. and the 40mg oral trip reports coming up, this may seem rather pale in comparison.
I do wonder though if mixing with lemon/lime juice would change the effects in any way, similar to with mushrooms. My own experience with mushrooms has shown that for me at least, powdered mushrooms with lime/lemon juice showed a much faster onset and a much shorter trip (around 2 hours).
After reading countless posts, both here and on the shroomery about if/how/why this changes the effects I think fastandbulbous had the most plausible theory, I don't claim to fully understand what he's saying, but he certainly seems to : ) here's a quote:
"As people have mentioned, using lemon juice means that in solution you have a lower (more acidic pH), meaning that the phosphate group isn't ionized and the amine group is a salt of a carboxylic acid (lower dissociation constant). Both of these increase the speed at which the psilocybin crosses the gut wall, producing a higher plasma concentration and in a shorter space of time.
It doesn't potentiate the drug, it just gets it into the bloodstream a hell of a lot faster (think about the effects from injecting/snorting/swallowing the same dose of amphetamine. It's the same dose, but injection feels stronger than snorting which feels stronger than swallowing; it's all to do with peak plasma concentrations, nowt else)"
Does anyone have any ideas as what may happen (if anything) chemistry wise to this compound in an acidic solution like lemon/lime juice? I may give this a try if there is any plausible reason to, but its not high on my priority list...