I'm currently taking the antibiotic ________ , and I want to take MDMA -- is this safe?
If you are sick enough to be taking an antibiotic, there is a good chance that you aren't healthy enough to take MDMA. MDMA supresses the immune system, making it easier to catch viruses and infections. Thus, if you are trying to fight an infection, and you take MDMA, there is a good chance that it will take you longer to recover from your infection. For this reason, it is strongly recommended that you wait until you are in better health before taking MDMA.
There are certain cases, however, in which the antibiotic is not being taken for reasons of poor health. For example, many people take doxycycline daily for acne. In a case like this, taking MDMA will not significantly affect the user's overall health.
If you do decide to roll, and there is no reaction between your antibiotic and MDMA (as per the lists below), then it is extremely important that you continue to take your antibiotic exactly as directed by your doctor. If you decide to stop taking your antibiotic for a day or so (because you want to roll, and your antibiotic interacts with MDMA), then make sure that you finish taking all your antibiotics after you roll.
Should I be worried about any interactions between my antibiotic and MDMA?
Most antibiotics are theoretically safe to combine with MDMA. I say 'theoretically' because although there are no forseeable interactions, there has been no medical research on the combination of MDMA and antibiotics.
There are a number of people who have rolled safely on antibiotics, and to date a bad interaction between an antibiotic and MDMA has never been reported. However, this does not guarantee that you won't have an interaction, so keep this in mind.
The following antibiotics should be, theoretically, safe to combine with MDMA (note that these are NOT brand names, but rather the chemical names):
cephalosporin, and forms of (cefepime, cephalexin)
isoniazid (used to treat TB)
nitrofurantoin (but this may cause oxidative stress and so MDMA would be best avoided)
The following antibiotics have the potential to be dangerous, because they inhibit one of the enzymes (CYP34A) that breaks down MDMA. Thus, you should be cautious (consider taking a 1/2 dose of MDMA) if you are taking one of these antibiotics. Antibiotics with a (*) indicate that people have rolled on this antibiotic safely -- though it is still recommended that you be careful with these.
doxycycline (common acne med) *
ketoconazole* (but person experienced a very strong, long roll - proceed with caution!)
Please note that this is NOT a complete list of all antibiotics -- if you are taking an antibiotic that is not on this list, PLEASE make a post in the Health Q&A Forum so that your antibiotic can be researched.
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