sonic said:According to rxlist: It (lorazepam) is a nearly white powder almost insoluble in water.
http://www.rxlist.com/cgi/generic/loraz.htm
Water solubility is usually a good indicator whether a substance can effectively be snorted or not.
trichr0me said:anyone know the bioavailability for focalin? All aspects?
trichr0me said:Does ADDERALL (DEXTROAMPHETAMINE) have a 75% or 25% oral bioavailability?
There were 2 different answers people posted, so I am trying to figure out what the oral bioavailability is...
Thanks!
enoughorangejuice? said:anyone know morphine's rectal BA compared to oral or IV?
Agreed, that's what it seemed like to me.nukka said:Adderall is only 50% dextroamphetamine (25% sulfate, 25% saccharate). The other 50% is similar but different, racemic levo-amphetamine.
The drug is designed to take orally, and IIRC the high-life is around 75%. I could be remembering this wrong, but I do know its substantially higher than 25%
All Bioavailabilities for other ROAs is relative to IV (which is 100% BA). Morphine has a shitty oral bioavailability at around 30% and based on experience and research I would place the bioavailability for rectal route at about the same. The only difference in this ROA is that it gets absorbed faster, kicks in faster, etc. causing a lot of people to think the BA is higher rectally but I have my doubts about that.
Short answer: oral/rectal is 30%, IV is 100%
the unknown said:then why does everyone feel just as high mg for mg when insuffulated or taken orally. Like i said everyone would notice if 20mg felt like only 10mg if insuffulated. It just doesn't make sense.
BollWeevil said:enoughOJ, where did you get that methylphenidate nasal absorption figure?