Dxm
First for ^ you think pocketing something in a store is less suspicious than buying a drug they sell?
They make 15mg dxm hbr gelcaps, generic and brand name, most stores carry them, some may not but i have seen them everywhere for cough and i have a few of the diff bottles here right now. 10, 20, 30, even 40 gelcaps is nothing to take compared to screwing with cough syrup.
There are 20 of these things in a bottle so its really not that outragious to buy 2 bottles at a time, hell go back in 30 minutes to a different cashier even.
Ive purchased multiple packages of things that were far more suspicious, noone really cares in my experience, the cashier is tired and pissed at the store for making her work all the time and only wants to go home and pop some vicodin and drink a glass of wine so she can forget the asshole boyfriend who screwed her sister and......well back to dxm
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For those of you who dont like DXM, the 2nd plateau is typically what people enjoy the most, but you have to go past the 1st to get there which isnt all that fun honestly.
Typically the 1st plateau is an intoxicating feeling, not too bad but not all that fun either, this plateau owes its activity primarily to the metabolite DXO, which is what most of <100mg will turn into in the body. DXO is an NMDA ligand, this is the receptor that produces the intoxicating effects.
The 2nd plateau is the saturation of NMDA receptors and the beginning of Pcp2 and Sigma1 receptor activity, from DXM itself. This is the stage most people shoot for and what most people enjoy. Its also not the easiest stage to hit, most people under or overshoot the mark and hate it afterward.
The 3rd plateau is dissociative just like ketamine or nitrous, feeling numb all over and having distant vision is common, some people feel this is a bad experience but in many cases people like it. If you know what ketamine dissociation feels like, this is fairly similar but somewhat different in cognitive effects.
The 4th plateau is full reality replacement, ive never done this with DXM but i have with ketamine hcl more than once, if you want to see what this plateau is like i have a trip report on BL from 2001
Here.
DXM is metabolised by the CY2D6 enzyme, it is O-demethylated into DXO, codeine follows this same path, turning into morphine by the same enzyme.
Having said that, i have been playing with the following idea: If one were to inhibit this enzyme you would probably get stage 2 effects from a lower dose, and totally skip and remove the first stage from the whole experience, at least for a while. Afterward metabolism would happen more slowly, though it WILL eventually turn into DXO at a slower rate, to a lesser effect and smaller impact.
I may try this and see what the advantages are, if i do i will post a real trip report in that section.