ex-amine,1mg is probably a good starting point.If it helps,here is my data with the hydrochloride of 2C-TFM.Moderator might switch this to trip reports.
A word of caution and a note regarding set and setting:I have a similar sensitivity as Shulgin and find the doses in PIHKAL very appropriate for me.I have experience in many rc's,traditionals,low to high doses.My threshold level for changes (in awareness,mood,body but also politics,economy etc) is low,the research opened my eyes to many things.The 2 low dose exp. below were done in a normal day work environment this year,the 5mg dose was tested in proper setting/set at home 7 years ago.
About 6 years ago I had to stop all research because I got from all psychedelic chemicals idiosyncratic overdose reactions with even lowest doses (aka 10mg 2C-T-7) with cramping,panic,stiff neck/shoulder,anxiety,this started right at the moment when the drug should have started to drop.It was followed the day after with depression/psychotic reactions which didn't subside without treatment (SSRI).So be careful for early signs like HPPD,mood swings,trips not ending fully etc.I still don't know what exactly happened,but it certainly had a large toxic and only physical component.I know of someone else which developed the same reaction after mainly 2C-B use (the purity of the compounds is not in question).If someone can help in a diagnosis or had a similar happening please let me know (it was not just a bad trip).
Earlier this year I started to take again small amounts of psychedelics,with usual response but the come down is still accompagnied by stiffness and an unease,but psychlogicallly I'm fully stable and I must say the few trips all have been a great success in regard of personal development,view of things etc..But I'm hesitating to take higher doses again (well,I have gotten to the highest levels,several +4's,even a +5 -I know its offscale-but what would you call full contact with God?,reached all my goals, so I think I can take it more lightly now
(with 0.6mg): "Alert in 15min,then nothing for a long time,at 48min something starts to develop,some mouth paresthesie,at 1h a clear threshold is reached climbing almost untraceable to a peak at around 3 hours.Mood is up considerable,there is some tactile enhancement but almost no visual component.It produced a stimulated,fresh feeling at the peak,maybe a +/- on the Shulgin scale.It started to drop probably at 5h,reaching baseline at 7-8h."
(with 1.25mg): "alert in 7min,probably because it has been dissolved in a too little amount of water (6ml) and got absorbed partially by sublingually.At 30min something develops,tactile enhancement apparent at 40min,well,is this a +1 at 1h?there is some visual enhancment developing,at 1.5h a slight shifting of objects is observed,colors,particularly iceblues and greens seem more pronounced.2h,maybe a +1.5,coffee break (synergism with caffeine ?),interaction with people is fine,clear thinking.A plateau is reached at around 3h,slight tremor,a relaxed buzz through my body and soul,but no CEV observed.What pops up again is the term "fresh feeling",good tactile enhancement,somewhere similar as 5-MeO-MIPT.Appetite is okay,not overwhelming but food tastes good.Dropping evident already at 4h,5h back to +1 with lingering aftereffects reaching basline at 8h.Sleep was normal,the 2.day fine."
(with 2mg,3mg,4mg,6.3mg): "like the preceding 2 new trials,planned experiments,in the proper way of running the compound up-I've gotten wiser (in 5 years without psychedelics...)"
(with 5mg): "This is a 7 year old experiment,in my old and very adventurous psychedelic beginning I would take the "right" dose right on.Well,it was the right dose,but I lost somehow my notes and this comes from memory.The compound came on silently starting at 25-30min,developed to a +3 plateau at around the 2nd-3rd hour,started to subside at 5-6h.Total duration was 12h,somewhat into the night,but sleep was possible after that mark.I concluded this to be a winner (unlike the earlier tasted 2C-EF),most remarkable was its caused "fresh feeling".far from antierotic.The visuals were not so pronounced,I remember few CEV,OEV were in the vein of 2C-B.Particularly the comparation to 2C-B was highlighted,but longer lasting.Knowing the term "CB like",I concluded that if there is an archetype of this class,it will be 2C-TF (as i called it then).With the dose range I'm reminded of DOM,the 1mg trial in PIHKAL etc.
And frankly,these 5mg felt safe that I intended to up it again. But a I had to take a long break from psychedelics"