It definitely does get dosed in the microgram range, but not nearly as low of a dose as LSD. But the dose-response curve is MUCH steeper than LSD's. You'd better not even attempt to weigh out a dose of pure salvinorin-a unless you have a prescription balance that weighs out micrograms. Back in the day when salvinorin was first isolated, I remember people telling me anything over 1 mg became pretty intense, and often led to blacking out with little to no memory of any experience taking place.
Assuming one has a prescription balance, and microgram weights, I would start off with 500ug and possibly increase by 100ug with each subsequent experiment.
Assuming one has a prescription balance, and microgram weights, I would start off with 500ug and possibly increase by 100ug with each subsequent experiment.