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Opioids Snorting Methadone?

Very interesting SpatChrome. I will probably try this. Im on 40mg of methadone a day for chronic pain. Im supposed to take 10mg 4x a day. I swallow 3 throughout the day and save one for snorting. I know just crushing and snorting all those fillers isnt good but I never thought about CWE for my methadone. My tolerance is up and I do not see my pain doc till mid March. I dont get this overwhelming euphoria from snorting 10mg but I do feel something. Contrary to what others have stated, I do get a buzz from methadone. Its not like oxy's or Opana by far but its something. The last 2 years since I was diagnosed with blood clots in my groin, Ive been on several opiates. I havent had anything else but methadone since I had a dose of Dilaudid in my IV a few months ago (THAT WAS GREAT) Methadone is all Im on. I remember the buzz of the other drugs but honestly, its been so long Ive kinda forgot the rush of anything else. So, Methadone is my opiate cause its the only one my Dr will give me. I make due with what I have and it does work. I guess if youre used to Oxy's, Opana, or Heroin, methadone aint nothing. But, for the rest of us who have low tolerance, methadone is great. Like anything though, it could be better. My next trick is to try to smoke it. Haha, well see. Thanks for the tip and woo hoo for methadone!!
 
I snorted 5mg's (half a 10) of Methadone last night and it BURNED, then I woke up this morning and my nose is totally plugged. What is the common/best way to take this stuff? Deal with the nose problems?

Just eat it. Snorting and injecting is pointless, the oral bioavalibility is near 100%
 
Very interesting SpatChrome. I will probably try this. Im on 40mg of methadone a day for chronic pain. Im supposed to take 10mg 4x a day. I swallow 3 throughout the day and save one for snorting. I know just crushing and snorting all those fillers isnt good but I never thought about CWE for my methadone. My tolerance is up and I do not see my pain doc till mid March. I dont get this overwhelming euphoria from snorting 10mg but I do feel something. Contrary to what others have stated, I do get a buzz from methadone. Its not like oxy's or Opana by far but its something. The last 2 years since I was diagnosed with blood clots in my groin, Ive been on several opiates. I havent had anything else but methadone since I had a dose of Dilaudid in my IV a few months ago (THAT WAS GREAT) Methadone is all Im on. I remember the buzz of the other drugs but honestly, its been so long Ive kinda forgot the rush of anything else. So, Methadone is my opiate cause its the only one my Dr will give me. I make due with what I have and it does work. I guess if youre used to Oxy's, Opana, or Heroin, methadone aint nothing. But, for the rest of us who have low tolerance, methadone is great. Like anything though, it could be better. My next trick is to try to smoke it. Haha, well see. Thanks for the tip and woo hoo for methadone!!

Why are you dosing multiple times a day? Given the halflife it's pointless. You could simply take them all at once. If you stop snorting one of your pills, as well you will probably experience a better high.
 
Thanks for the advice. Ive read a lot about methadone but, honestly, dont really understand halflifes and bioavailability and stuff. I mean, I understand it but not too much detail. Im not sue. All I know is that my pain Dr prescribes this to me just like that. 10mg 4x a day. He keeps mentioning building a pain barrier wall and keep it consistant thru the day. But, I dont get up in the middle of the night to take it so wth? I can only go on what he says. I have read on multiple sites that methadone for chronic pain is grossly underprescribed. He thinks Im on a high dose now. He has raised it alot though. I started on 10mg....yes 10mg a day. Trying to split 5mg pills and taking it 4x a day. They would just crush apart when I tried to split them so I said...hmmmm, I could just snort one. I think its more part of the ritual than anything else. It must be. Why would I snort a med that had 100% oral bioavailability? Uuugh. I have no history of abuse. I have huge blood clots from the top of my belly, all the way down to both knees. Im almost blocked off in my groin area and thats where all the pain is. The meth dulls it but not for long. Its sure better than nothing but I believe there could be a better way to go about this. I asked him about my breakthru pain and he just shook his head and told me thats how addiction starts. Wth? The only thing that really cracks my pain is Dilaudid in the IV at the ER. Obviously, I cant get that level of pain relief every day but I wish I could!! Its really more about pain relief than it is about getting high. If I get a buzz and stuff, thats great though, hehe. Its always around a 5 or 6 out of 10 on the pain scale. When my tolerance builds, it goes to 8 or 9 and I cant walk. Im seeking second opinions finally so maybe the new hospital system will be more forgiving. The clots aint goin anywhere. Theyre all hardened and scabbed. Surgery failed, twice. Well, after reading this, do yall think 40mg once a day in the morning would be more benificial for my pain....and my buzz? Thanks for reading all this and suggesting an alternative. Later.
 
Guido said:
Just eat it. Snorting and injecting is pointless, the oral bioavalibility is near 100%
Although the bioavalibility is high, injected methadone is twice as strong as oral. This is because brain concentration are much higher when injected.Plus methadone takes like two hours to kick in, up to 8 to peak. Snorted and sublingual is like 10 minutes and IV instantly.
Why are you dosing multiple times a day? Given the halflife it's pointless. You could simply take them all at once. If you stop snorting one of your pills, as well you will probably experience a better high.
Addiction maintenance is once a day. For pain methadone is taken 3-4 times a day; the analgesic effects are shorter then the half-life.

I've tried it sublingually, and it did kick in faster. Numb my mouth, but also burned. It must hurt to snort.
 
Although the bioavalibility is high, injected methadone is twice as strong as oral. This is because brain concentration are much higher when injected.Plus methadone takes like two hours to kick in, up to 8 to peak. Snorted and sublingual is like 10 minutes and IV instantly.
Addiction maintenance is once a day. For pain methadone is taken 3-4 times a day; the analgesic effects are shorter then the half-life.

I've tried it sublingually, and it did kick in faster. Numb my mouth, but also burned. It must hurt to snort.


Actually, IV'd methadone, as stated on wikipedia and several other sources on the internet, doesn't produce any rush and it's peak plasma levels are reached in the same amount of time as simply just injesting it. Methadone tablets, like suboxone tablets aren't meant to be injected. They are long acting opiates. Shooting methadone is on the same spectrum as snorting tramadol or codeine. It's needlessly pointless and naive.
 
I was on Methadone for 5 years I was going to a clinic to get it but that got old ame i found a Dr. to prescribe it for me. I was getting 160mg a day. That is 480 methadone 10mg pilla. I was also getting 90 xanax bars and 150 Narco10/325 EVERY MONTH. Needless to day the Dr. Was just a drug dealer with a medical license. It was not is fault Hell I sought him out. June 6th 2010 I had a seizure while diving and slammed in to the back of a tractor trailer. I shattered my pelvis, broke both arms, and split my head open. Thank God I was the only one ahí was hurt. The seizure was caused due to prolongd use of Methadone and Xanax. I now have 11 plates and 73 screws in my body. 3 mo later when I was learning how to walk again I had to have my left hip replaced. All the plates and screws on my pelvis rubbed all the cartledge of of my hip. I am 40 years old and I have to use a walker. I went to detox then rehab and as of today I am clean. NOW FOR THE KICKER. I was originaly sent to the Methadone clinic because I had a 6 lortab10/500 a day habbit. Oponga being at my worst I was taking ( minimum ) 160mg methadone and bars a day I would trade my 150 narco for 120 methadone. With the 480 a mo I got I was taking 200mg a day. All that happend was MY FAULT. I just went to let the people that feel thay are traped that there is hope. Methadone is COULD be a good program of Dr's. and clinics would follow it. It is supposed to be Methadone MAINTENANCE a 21 DAY program and not a way of life. I am sorry of anybody is offended. I have been clean now since 10-18-2011.
 
I learned a highly valuable lesson with both saline and water solutions of 10mg methadone/mL, and my advice is as follows:

NEVER INSUFFLATE METHADONE FROM PILLS.

Worst pain I have ever experienced, worse than any 2C-B or its cousins, worse than methamp which only stings a tiny bit.
 
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Thanks for the advice. Ive read a lot about methadone but, honestly, dont really understand halflifes and bioavailability and stuff. I mean, I understand it but not too much detail. Im not sue. All I know is that my pain Dr prescribes this to me just like that. 10mg 4x a day. He keeps mentioning building a pain barrier wall and keep it consistant thru the day. But, I dont get up in the middle of the night to take it so wth? I can only go on what he says. I have read on multiple sites that methadone for chronic pain is grossly underprescribed. He thinks Im on a high dose now. He has raised it alot though. I started on 10mg....yes 10mg a day. Trying to split 5mg pills and taking it 4x a day. They would just crush apart when I tried to split them so I said...hmmmm, I could just snort one. I think its more part of the ritual than anything else. It must be. Why would I snort a med that had 100% oral bioavailability? Uuugh. I have no history of abuse. I have huge blood clots from the top of my belly, all the way down to both knees. Im almost blocked off in my groin area and thats where all the pain is. The meth dulls it but not for long. Its sure better than nothing but I believe there could be a better way to go about this. I asked him about my breakthru pain and he just shook his head and told me thats how addiction starts. Wth? The only thing that really cracks my pain is Dilaudid in the IV at the ER. Obviously, I cant get that level of pain relief every day but I wish I could!! Its really more about pain relief than it is about getting high. If I get a buzz and stuff, thats great though, hehe. Its always around a 5 or 6 out of 10 on the pain scale. When my tolerance builds, it goes to 8 or 9 and I cant walk. Im seeking second opinions finally so maybe the new hospital system will be more forgiving. The clots aint goin anywhere. Theyre all hardened and scabbed. Surgery failed, twice. Well, after reading this, do yall think 40mg once a day in the morning would be more benificial for my pain....and my buzz? Thanks for reading all this and suggesting an alternative. Later.

Find a different (pain specialist) doctor You're right...WTF !
 
This is true its definately not a fast acting drug and it depends on the person when relief is felt but ive snorted it when in wd and it works if u only have 1 and you have a tolerance
 
Actually, IV'd methadone, as stated on wikipedia and several other sources on the internet, doesn't produce any rush and it's peak plasma levels are reached in the same amount of time as simply just injesting it. Methadone tablets, like suboxone tablets aren't meant to be injected. They are long acting opiates. Shooting methadone is on the same spectrum as snorting tramadol or codeine. It's needlessly pointless and naive.

WRONG. IV methadone under 15 mins, same with nasal administration. Yes it will burn a little bit, even with turning the pills into soln. then filtering, though it burns a lot less in my experience.

I'm quoting my post from months ago again,

I will usually take my methadone doses orally (65% of the time), but I rather enjoy doing intranasally. I tried it after reading all the negative reviews months and months ago, and noticed the typical annoying irritation of the roxanne methadone tablets like everyone else. However, I did notice a some differences in onset. My nose isn't in the best condition after years of snorting various substances I will say, with ketamine imo being one of the likely suspects to have caused the most damage to it, but speculation (not hating on k, it just seems to cause more bleeding, discomfort than other substances). So because of trying to maximize the amount of the drug actually being able to be absorbed, I tried a CWE in a 5-mL oral syringe, then transfered the solution with as little of the solids into a 50-ml erlenmeyer flask. I then used a 1-mL oral syringe for nasal administration trying to pull up as little solids . I squirt .10-.20 mL of solution into each of my nasal passages every couple mins (till they feel primarily dry), and repeat. I usually nasally dose when I have very few methadone and need trying to avoid WDs, or after I've taken oral doses for a higher dose of methadone. With this method I find that the methadone starts to effect me around 3-5 mins after getting atleast 25% of the solution (10mg total solution for example) absorbed. I will reach the peak probably around 30mins, but potentially could be alot less if I would snort it faster (I get distracted) - the tmax in the study I post below have results of 0.12h (+/-0.07-0.177). The BA from my experience seems as high, if not higher than oral at times (sometimes oral can very, juts like studies show). I also found it's primary high effect to last maybe 2 hours shorter than orally, but it's pretty much the same.

I just recently decided to create a little filter apparatus to transfer the solution of methadone into the flask with a lot less solid material and noticed an increase in the speed of the come up, as well as a lot less irritation. It was no worse than snorting powdered k, once the solution is filtered through the bit of coffee filter and cotton ball. Also using a 1-mL syringe it a must. You want to only snort .10-.20 mL max if you want majority of it to be absorbed orally.

Heres a study supporting all of this nasal administration being similar to intravenously (a good alternative to IV), and no negative aspects against oral consumption. The only problem would be if you are trying to consume large quantities of methadone. Since the tablets only come in 5 and 10mg, there is a lot of binder and filler. I have roxanne 5mg tablets and for 10mg, I'll use around 2mL. In the study below they have 50mg/mL, so you could reduce it and ingest large amounts in a relatively short period of time.

http://paincenter.wustl.edu/c/BasicResearch/documents/ClinPharm2002.pdf


So if this study is correct, I might dose my 5mg QID using this method. Or at least for my last dose before bed. It honestly gives me as good of a rush as oxycodone insufflated, but it comes down to a steady concentration in 20-40mins, so i can honestly say it does give a rush.

Give it a try, especially if you have a micron filter or even make a ghetto one. There is not much of a burn to notice, just a little tingling that disappears in less than a min.
 
snorting the pill? no way... but extracted methadone? carefully

"Snorting definitely gives you more of a rush and euphoria. Whilst the effects don't necessarily last longer via oral injection, the end of the 'rush' will feel like it's wearing off. When infact it isn't, your mind is just comparing how it felt during the rush to now. They have about the same half-life in your body.

Also because snorting has a rush and that rush ends, you will feel oh-so-tempted to re-dose. I'm not going to talk about the dangers of addiction because that is obvious but each time you re-dose you will need MORE to achieve that same rush. And trust me, you WILL want the rush back.

If you take it orally there's no rush as such, it's more of a calm, but focused and motivated feel.

So all in all.

Oral if you want to use it as a life tool."
 
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^^^^

What's the difference? They want us to use the search engine rather than post a new thread.
There's not that much going on in these forums anyway.
I'm with u headcase- I post a similar topic and I'm asked to look at search engine. :-/
 
I promote people experiencing short acting opioid WD that is severe to use alternate routes for ingesting methadone so you don't throw it up (which has happened to a friend), to dissolve the methadone pills into water, filter, then waterline the aq. methadone. It hits within 15 minutes, so it can pull you out of WD a hell of a lot faster than oral use. It also works nice also for pain. Methadone is great for pain (for those who it helps of course), so for those who may need extra relief quick, 10-20mg nasal can work ok for some break through pain. Oral methadone does not work at all for break through pain.
 
^^^^

What's the difference? They want us to use the search engine rather than post a new thread.
There's not that much going on in these forums anyway.
I promote people experiencing short acting opioid WD that is severe to use alternate routes for ingesting methadone so you don't throw it up (which has happened to a friend), to dissolve the methadone pills into water, filter, then waterline the aq. methadone. It hits within 15 minutes, so it can pull you out of WD a hell of a lot faster than oral use. It also works nice also for pain. Methadone is great for pain (for those who it helps of course), so for those who may need extra relief quick, 10-20mg nasal can work ok for some break through pain. Oral methadone does not work at all for break through pain.

Waterline? What does that mean?
 
^^ my god, worse than 2cb? that stuff was incredibly eye-watering



and rob, 200 a day? thats verging on premeditated assault. god save us from these inept practicioners
 
Methadone does not suck to the person up there who said that...go take 300 mgs and get back to me....anways just take the pills orally...the bioavailablity is pretty good by just taking it orally....ive heard of people plugging it (wouldnt do it myself but just saying) and they had really good experiences....anyways I am currently in MMT(methadone maintenance treatment) and I suggest simply taking it orally if its the 10 mg pills....if its the 40 mg wafers or diskettes...dissolve it in water and mix it,..it will taste like crap soo have something to drink it with after...
 
and remember it takes a while to kick in....about an hour n half til onset.........
 
I take about 60mgs of Methadone per day and I snort them every single time. The first few times I did it, it definitely did burn. But now I absolutely love the taste and feel. I wouldn't take them any other way. I snort a half of a 10mg pill about 12 times per day. It's way better then popping one, you get an instant 5mgs of methadone to your bloodstream 12 times per day. It's heavenly. My favorite to snort are the 57 71 rectangular wafers. Even since the beginning these didn't burn for me in the slightest. I also frequently take the 54 142 circles and those definitely are harsher then the wafers, but still wouldn't waste one by popping it. I total about 5-6/day and days that I do swollow them (with family, at work, etc) I take more like 8-10 and I still don't feel like I got the full worth of them. These are by far the best med I've come across as have been my daily for about 3 years. I've frequently snorted oxys, morphine aderall in the past but since snorting methadone daily, I have no desire for those. Everyone is different though. A lot of it is likely the way my nose is now. I snorted ALOT of coke for about 4 years that ate away a good portion of my nasal cavity. I'm sure this is a good reason to why snorting Dones really don't bother me. But even if you think it burns bad, I still think it's worth every bit of it to take this way vs eating. I would never IV Myself so cannot comment on that.
 
If I am mistaken, please someone correct me, but I have heard that whomever makes the methadone puts in Capsasin in it to deter those from snorting or spooning (IV) it. If you put one under your tongue and let it melt it will also burn. There really is no getting around the burn. Either pop em and take 1000mgs of vitamin c or snort it and deal with the burn. Always ALWAYS rinse out your sinuses after whatever you snort no matter how much it may suck or hurt. Do it a few times until your nose is no longer plugged. Blow your nose the next day to get as much of the binders out as possible.
 
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