Trinity, your first responce to his question was, "It supposedly increases the effects". This is simply wrong. He was asking if grapefruit juice potentiates codeine, and you implied that it did. Then you posted again saying it worked with oxycontin, which is besides the point. The question was about codeine, and grapefruit juice does not potentiate codeine. If the needle is "rotting my brain", despite that I was correct, what is your excuse?
Im not trying to start a flame war, but you did make a cheap shot with the needle thing, which has nothing to do with this thread, and you were incorrect in saying it supposedly increases the effects. Supposedly is a loaded word, and doesnt mean your statement was necessarily subjective. If you werent sure if it potentiated codeine, then why post at all?
Also that globalrph thing is just an error, codeine theoretically would be potentiated by grapefruit juice, being that it is an opiate, but in practice it does the opposite. There are many other references that support that codeine is not potentiated by grapefruit juice or tagamet and decreases its conversion into morphine, it is simply a fact. CYP2D6 activation to morphine is central to codeine's effects, so its inhibition by substances such as grapefruit juice or tagamet would without a doubt weaken codeine's high.
So if you think grapefruit juice potentiates codeine go ahead, but your simply wasting it, becauses it doesnt.