kokaino
Bluelighter
- Joined
- Sep 8, 2007
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On plugging morphine:
"The Bioavailability of Rectally Administered Morphine", Torsten Jonsson, Christian Broen Christensen, Henrik Jordening, Carsten Frølund
Abstract: Plasma concentrations of morphine were followed for 24 hours in eight patients after intravenous and rectal administration of 10 mg morphine chloride. The plasma levels of morphine were determined by a sensitive and specific radioimmunoassay based upon an extraction procedure which separates morphine from its major polar metabolites. The bioavailability of morphine after rectal administration was found to be 53.3 ± 17.8% (mean ± S.D.). Peak concentrations of 16.3 ± 8.7 ng ml-1 were reached after 59 ± 16 min. The study indicates that first pass elimination of morphine may be partially avoided by rectal administration.
That's a range of 36-71 mg BA rectally. It says it right on Wiki with the exact same study cited. It's an old study, more recent studies have given the rectal administration of morphine slightly higher . Either way, at those BA levels, rectal morphine would be stronger than oral oxycodone.