Mental Health Nozinan (levomepromazine)

At first glance it looks to me to be some sort of promethazine derivative, yet in my experience Seroquel is a much stronger sedative than any reasonable dose of promethazine (although the two do share a few similarities in the type of sedation feeling they produce), so it must be many times more potent.

Seroquel definitely makes me feel emotionally numb; Ive often used it in the past as a kind of...off switch, for lack of a better description, when I felt overwhelmed and just wanted to cut everything out. Im fairly sure Im also familiar with the feeling of peace that youre describing...its quite unlike benzos or alcohol...and in many ways I would describe it as more like a sensation of mental anesthesia than anything else.

Needless to say, if this substance is as much more powerful a sedative compared to Seroquel as you say, be very careful with it.

I figured id post this dosage information since i found it interesting especially the large differences in mgs depending on use .

"Levomepromazine
Indications
Lised in Dosage.
Dosage
Adult : PO Schizophrenia As maleate: 25-50/day in 3 divided doses, w/ higher dose at night. Non-ambulant: 100-200 mg/day. Max: 1g/day. Adjunct in severe terminal pain; Nausea and vomiting As maleate: 12.5-50 mg 4-8 hrly. Sedation 10-25 mg at bedtime. IV/IM Adjunct in severe terminal pain; Nausea and vomiting As HCl: 12.5-25 mg 6-8 hrly. Severe agitation: Up to 50 mg IM Acute pain As HCl: 75-100 mg in 3-4 deep inj. Post-op pain As HCl: 10-25 mg 8 hrly, 2.5-7.5 mg 4-6 hrly if residual effect of anesth present. Premed in surgical procedures As HCl: 10-25 mg 8 hrly . Final pre-op dose: 25-50 mg approx 1 hr before surgery"


http://www.mims.com/philippines/drug/info/levomepromazine?mtype=generic

Crubsc so your saying you take
Quetiapine 600 mg
Levomepromazine 200 mg
Clonazepam 6 mg
Vaplroic acid (depakote) I take that too

Do you have some type of mental illness like bipolar disorder or schizophrenia?

The reason I ask is I dont think what any person who happens to take levomepromazine one time will generalize very well to you. I think you might be better off focusing on people who have a similar reason for why ever your prescribed those meds and how they did LONG term.

For example, when I took depakote for the first time if all i did was report what happened youd get "I took it made me kinda sleepy and it was hard to walk for a few hours after taking it" vs long term "it gives me no side effects and my mood does seem to be more stable"

I'm going to fix this so you have your own thread and move over to Mental Health for you.

Hey d1nach

Thanks for your reply!

That's right, I take exactly those meds in that "amount"... You asked if I have some type of mental illness: well, I'm not bipolar, but my pdoc says I have "unspecified mood disorder", some psychiatrists talk about "a mood disorder spectrum", you can read more about it here. http://www.psychiatrictimes.com/film-and-book-reviews/spectrum-approach-mood-disorders

I also have had, and I think I'll always have, substance abuse disorder, more specifically cocaine and to a lesser extent alcohol.

You also mentioned your experience with Depakote, I don't remember feeling sleepy on it, even when I first started it. When I started Quetiapine though, it did make me drowsy, but nothing compared to when I started Nozinan, which was when I was hospitalized (for substance abuse)... The difference, in my opinion and in my experience with these drugs, is that the drowsy side-effect passed after a couple of weeks while on Quetiapine and nowadays I don't feel sleepy at all when I take Quetiapine (I read in a topic here on Bluelight that the smaller the dosage, the more sleepy you'd feel on Quetiapine)... Nevertheless, I do know that Quetiapine helps a lot with my anxiety and mood swings... My reaction to Nozinan has never changed though, it always makes me "peaceful" and also sleepy, sometimes more sleepy, sometimes less sleepy, it depends on the day, I don't know why. I have always taken 100mg pills, first once a day and then twice a day... After lunch I take 100mg of Nozinan and 200mg of Quetiapine... Let's say I take it at 1PM, by 3PM I'd feel relaxed and a bit drowsy, sometimes more sleepy... I can carry on doing my things, but sometimes I do need to take a nap...

As for Clonazepam, it does absolutely nothing to me at my current dosage (it only prevents me from withdrawal, since I became addicted to it, unfortunately), for me to feel the calming effect of it, I'd have to take at least 10mg and even so, it's not (obviously) as potent as Nozinan (or Quetiapine), as far as a "calming" effect is concerned.

(Sorry for my mistakes in English)

Greetings from Brazil ! Cheers!