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Asante
27-04-2013, 11:58
A friend smoked an unknown amount of rh-34, thinking it was a cannabinoid. He was tripping balls for 10 hours. Will try it myself soon.


/me's ears perk up!

Can you find out more information about this from the friend? Approximate amount, character and quality of the experience etc?

Psychonaut69
27-04-2013, 13:29
He described it as a real bad trip/psychosis, seeing all kinds of images from memory first, then leading to complete ego loss and uncontrollable mental thought processes. He wasn't expecting any of that which may have triggered the bad trip. I was unable to find out how much he used.
So in order to try to recreate this experiment and verify his findings, I smoked about 3-5 mg myself last night which triggered a very mild psychedelic experience, but this may have been a placebo effect as there was a lot of weed involved as well. Will try to smoke ~10 mg next week but I wonder if the creatine (it's supposedly 90% creatine, 10% RH34) poses a health risk when smoked.

Asante
27-04-2013, 14:17
Please be VERY careful. The jump from 3-5mg to 10 is too high.

An unexpected very strong trip that comes on fast is a perfect recipe for a bad trip, so it need not be the drug itself but as you think too, because of the surrounding circumstances.

Its REALLY unfortunate that theres 90% Creatine in the mix, if its mixed unevenly theres no telling what dose you are taking and creatine is chock full of nitrogen, because of its guanidine component, which upon combustion might generate nitrogen oxides. If you do it, you'll have to vape it very cleanly.

jesuspeople666
07-05-2013, 23:33
any updates?

bloodshed344
08-05-2013, 00:27
Yeah this chemical sounds fascinating.

The Lone Deranger
08-05-2013, 03:10
Yeah this chemical sounds fascinating.


Yeh smoking creatine does sound very intresting, bit like a body builder that cant put the pipe down ?

Sorry BTW, know its not constructive, but could'nt help myself .. But seriously why do you think it sounds fascinating ? i mean everyone thats tried it has come up with a fail .. sounds like a waste of time to me ..

crOOk
08-05-2013, 09:47
Yeh smoking creatine does sound very intresting, bit like a body builder that cant put the pipe down ?

Sorry BTW, know its not constructive, but could'nt help myself .. But seriously why do you think it sounds fascinating ? i mean everyone thats tried it has come up with a fail .. sounds like a waste of time to me ..QFT (and lol at smoking creatine :D )

edit: Btw guys, I explained to you how to separate the substance from the creatine. It's a very easy process...

plusfourpirate
08-05-2013, 10:15
Yeah this chemical sounds fascinating.
i take it youre being facetious?
it sounds pretty sketchy to me so far. :)

crOOk
08-05-2013, 10:37
I wish there was a general tendency on bluelight to get back to things like DMT Mushrooms and Mescaline. All these crazy-ass rc's don't really seem to offer any advantages over the naturally occuring psychedelics at all, besides being cheap and available. I myself have abused the shit out of psychedelics, but in all honesty I do not think it's anything anyone should do who wants to live a functional life in westerm society. So why the need for cheap psychedelics that carry unknown risks that can be ruled out for classical psychedelics?
The whole issue is a bit puzzling to me. I'm curious as well when it comes to "new stuff" as I have demonstrated with my own trials, but I just don't see why anyone would go back to these substances over and over, especially the NBOME series which seemed pretty shitty to me personally. I would strongly urge anyone who is into rc psychedelics and has never experienced mescaline or dmt to schedule an appointment with these 2 substances. :D

Btw I'm wondering if the dude who smoked it and had a bad trip just experienced a very strong synthetic cannabinoid intoxication, since there were so few details about his experience. I have heard that these cannabinoids can be absolutely mind shattering for some people (I personally just get very stoned and dizzy/sick on a high dosage of AM2201).

bloodshed344
08-05-2013, 13:01
I really think it sounds fascinating guys. I want to hear a real trip report, and to The Lone Deranger... I couldn't find anyone who has actually tried it aside from the post near the top of this page, but it doesn't sound real for whatever reason.

crOOk
08-05-2013, 13:38
I really think it sounds fascinating guys. I want to hear a real trip report, and to The Lone Deranger... I couldn't find anyone who has actually tried it aside from the post near the top of this page, but it doesn't sound real for whatever reason.Not sure if you are referring to my trials or the accidental ingestion by that other guy... I should've made it sufficiently clear that I experienced nothing but threshold effects at astronomical dosages. I'm a pretty long-standing member here and can't remember anyone ever doubting my credibility on this site either. The accidental ingestion does sound a bit sketchy indeed if that is what you are referring to.

I still don't feel your fascination after all the reports about it's inactivity. It actually sounded pretty hot to me as well before info about all those failed trials was beginning to be posted.

Edit: If you are actually doubting the realness of my trip reports, I'd like to point out that you are walking on thin ice, having joined in early 2012 and sort of promoting a substance that a few vendors have available in large excess after it has been assumed to be without psychedelic effects... I'm not suggesting anything really, just saying that most anecdotes about this substance are in congruence with my own poor results and your "fascination" for this substance is puzzling a few members here. What exactly do you find "fascinating" about it? Are you a biochemist or something?

bloodshed344
08-05-2013, 14:56
Not sure if you are referring to my trials or the accidental ingestion by that other guy... I should've made it sufficiently clear that I experienced nothing but threshold effects at astronomical dosages. I'm a pretty long-standing member here and can't remember anyone ever doubting my credibility on this site either. The accidental ingestion does sound a bit sketchy indeed if that is what you are referring to.

I still don't feel your fascination after all the reports about it's inactivity. It actually sounded pretty hot to me as well before info about all those failed trials was beginning to be posted.

Edit: If you are actually doubting the realness of my trip reports, I'd like to point out that you are walking on thin ice, having joined in early 2012 and sort of promoting a substance that a few vendors have available in large excess after it has been assumed to be without psychedelic effects... I'm not suggesting anything really, just saying that most anecdotes about this substance are in congruence with my own poor results and your "fascination" for this substance is puzzling a few members here. What exactly do you find "fascinating" about it? Are you a biochemist or something?

It's a strange concept, ketanserin-nbome. I didn't see your results however, I'll look again.

Also, the last part of your post sounds pretty sketchy, are you on stimulants? Hahaha.

unfuckwitable
08-05-2013, 15:37
i am of the mind this is one to LEAVE ALONE. the danger with this one, so it seems, may be people ingesting massive doses attempting to achieve psychedelic effects when it is very possible RH-34 may not be effective in this manner, if not with extremely limited efficacy. even following a future trusted sources' bioassay, the recent influx of various 5-HT 2A agonists, namely the NBOMe series have already incited enough frenzy, falling into the wrong hands & culminating in several deaths. as the reports of fatalities & hospitalizations keep pouring in, you have to wonder how many we DON'T hear about. the omnipotent nature of (most of) these compounds, difficulty, even impossibility calculating desired and/or "safe" dosage, common moderate to severe vasoconstriction, etc. are far too precarious for even expert-level individuals to experiment with. until more comprehensive research is exacted & more becomes known than just the bare bones, minimal amount of information currently available, this material (trusted vendor or not) need be approached with extreme caution, if not avoided altogether.

personally, i wouldn't touch RH-34 with a thirty-four foot pole, though inevitably, someone will take irresponsibility to its' pinnacle and dive head-first into this stuff. please be careful out there, folks.

crOOk
08-05-2013, 18:38
It's a strange concept, ketanserin-nbome. I didn't see your results however, I'll look again.

Also, the last part of your post sounds pretty sketchy, are you on stimulants? Hahaha.No I'm not on stimulants at all, I'm bipolar 1 though which can affect my speech to a degree that leaves me entirely unable to form comprehensible sentences. Thanks for pointing that out though! English also isn't my mother tongue.

It is a strange concept and it seemed interesting before all the reports about it's apparent lack of psychedelic activity surfaced.

ebola?
08-05-2013, 22:49
But seriously why do you think it sounds fascinating ?

A psychedelic based on an entirely novel backbone (structurally distinct from ergolids, phenethylamines, and tryptamines)? That is fucking intrinsically fascinating (too bad it's not seeming to pan out)! :)


I wish there was a general tendency on bluelight to get back to things like DMT Mushrooms and Mescaline. All these crazy-ass rc's don't really seem to offer any advantages over the naturally occuring psychedelics at all, besides being cheap and available.

I personally respond way better to compounds that are selective for 5ht2 over 5ht1 (as broader spectrum serotonin agonists can be nightmarishly anxiogenic and confusing for me), and it's nice to have compounds that last 4-8 hours rather than 12-16. Nothing found in nature, nor LSD, offers this.

ebola

crOOk
08-05-2013, 23:22
A psychedelic based on an entirely novel backbone (structurally distinct from ergolids, phenethylamines, and tryptamines)? That is fucking intrinsically fascinating (too bad it's not seeming to pan out)! :)Yeah of course, if only it was a psychedelic. ;)

zn13bt
08-05-2013, 23:53
I wish there was a general tendency on bluelight to get back to things like DMT Mushrooms and Mescaline. All these crazy-ass rc's don't really seem to offer any advantages over the naturally occuring psychedelics at all, besides being cheap and available. I myself have abused the shit out of psychedelics, but in all honesty I do not think it's anything anyone should do who wants to live a functional life in westerm society. So why the need for cheap psychedelics that carry unknown risks that can be ruled out for classical psychedelics?

Uhh, because all of the ones that are known to be safe have been made illegal throughout the world?


The whole issue is a bit puzzling to me. I'm curious as well when it comes to "new stuff" as I have demonstrated with my own trials, but I just don't see why anyone would go back to these substances over and over, especially the NBOME series which seemed pretty shitty to me personally. I would strongly urge anyone who is into rc psychedelics and has never experienced mescaline or dmt to schedule an appointment with these 2 substances. :D

I have tried both mescaline and DMT a handful of times each, and I still prefer 25I-NBOMe to both of them. It's a highly personal thing which psychs each of us happen to like or dislike. That being said, this RH-34 isn't sounding like it's working well for anyone. But still, it's a good thing that we have a forum for discussing new substances and sharing information about them, isn't it? And as long as governments keep banning old substances that are tried and proven, there will always be new ones cropping up.

crOOk
09-05-2013, 07:39
I have tried both mescaline and DMT a handful of times each, and I still prefer 25I-NBOMe to both of them. It's a highly personal thing which psychs each of us happen to like or dislike. That being said, this RH-34 isn't sounding like it's working well for anyone. But still, it's a good thing that we have a forum for discussing new substances and sharing information about them, isn't it? And as long as governments keep banning old substances that are tried and proven, there will always be new ones cropping up.You have, but how people on here who are into those novel psychedelics have? I also strongly doubt that the legal issues are a major issue for most people. E.g. most people who do psychedelics also smoke pot which is illegal just about anywhere. I don't see many people falling back to synthetic cannabinoids because they aren't allowed to smoke pot.
You do have a few valid points there, but I didn't really mean to say these that novel psychedelics pose no advantages at all over classical psychedelics (which I did though lol). It's just a shame that a drug like mescaline (which to me is by far the most rewarding of all psychedelics) is almost forgotten about, while people are dying after consumption of amateurishly laid NBOME blotters.

zn13bt
10-05-2013, 00:54
But clearly the illegality of marijuana has created a growing market for synthetic cannabinoids. Likewise with MDMA and 6-APB (and mephedrone before it). And many of the websites which sell these sorts of "legal highs" also were (and still are?) selling NBOMes. Which turned out to be a terrible idea, since those kinds of customers typically don't have a lot of experience with highly potent chemicals, and can't be bothered to research how to handle them safely. Also they seem to be more interested in using these substances for recreation instead of personal and spiritual growth, so I doubt mescaline or DMT would appeal to very many of them anyway. That's the impression I've been getting from watching the NBOMe B&D threads over the past year and a half. It's not experienced psych users who are having problems with NBOMes, as far as I can tell.

I do agree with you that we should all be careful about how we're discussing novel psychs here, making very sure we're not excessively hyping them or contributing to unwarranted speculation about their potential effects.

crOOk
10-05-2013, 02:57
Yeah, you really spoke my mind there. I always end up sounding way too extreme when I try to throw my opinion out there. The fact that hedonistic/masturbatory qualities seem to be a primary motive for ingestion of psychedelics in many people is what really gets me so worked up over all this. The popularity of NBOME's seems to be a symptom of this circumstance, resulting from their availability. I hear so very little talk about those extremely safe psychedelics that have always been available, it's a bit disheartening, knowing how amazing they are. With all these new rc's came thousands of new bluelighters and the formerly dominating spirit of internet drug users seems a bit overshadowed by all this.

Transform
11-05-2013, 16:10
Actually google indicates the opposite (http://i.imgur.com/mLAmVLa.png) trend crOOk.

I don't think we could assign a lot of significance to this, but I think if it was attracting us more registrations then more people would be searching for us by name.

Toucan
11-05-2013, 16:52
With each new chemical that crops up there is a whole realm of new discussion that needs to be had. A lot of questions that haven't been answered, or even asked yet. This isn't an influx of new users, just fresh discussion.

Never Knows Best
11-05-2013, 17:02
I hear so very little talk about those extremely safe psychedelics that have always been available, it's a bit disheartening, knowing how amazing they are. With all these new rc's came thousands of new bluelighters and the formerly dominating spirit of internet drug users seems a bit overshadowed by all this.

The info is already out there for the most part, and we do get tons of shrooms/LSD/DMT discussion.


All these crazy-ass rc's don't really seem to offer any advantages over the naturally occuring psychedelics at all, besides being cheap and available

That's a big part of it too, availability. Plus a smaller percentage of persons in illegal drug scenes are gonna be on a board such as BL than persons in the RC scene.

kidklmx
11-05-2013, 17:09
I dunno cr00k, what is there to be said about LSD, Mescaline and DMT that hasn't already been said? These novel RCs are so heavily discussed because they are, in fact, novel.

tamarinds
11-05-2013, 17:21
So is RH-34 worth a shit?

Anybody had their amount third party tested for identity?

Ive got a feelin this one sucks big time

crOOk
11-05-2013, 17:56
Noone I know of has had his third party tested. If the substance being sold (with 90% creatine as cutting agent) is in fact RH-34 it does not seem worth a shit at all. ;)

tamarinds
11-05-2013, 18:32
Buying something with a cut is silly shit brother. And makes the source super not trust worthy. Sell the pure people, let Darwinism take its course.

I still bet this shit sucks.

unfuckwitable
11-05-2013, 19:07
let Darwinism take its course.


insert startrek.facepalm.jpeg

tryp2fun
11-05-2013, 20:03
Hasn't anyone bothered to look at Ralf Heim's dissertation? (Ralf Heim = RH!) OK, it is in German, but the tables are easy to read. RH-34 is a low affinity agonist at 5HT-2a receptors, about 20% that of 2C-B, so based on that it shouldn't be active until about 80-100 mg. (Mod edit: do not try such a high dose!! Read further why...) Nevertheless, a proper titration is in order. What was interesting about RH-34, of course, is that the 2-methoxybenzyl group made an antagonist (Ketanserin) into an agonist. This led to the preparation of the N-BOMe derivatives of the 2C-Xs, and the rest is history.

ebola?
11-05-2013, 22:56
(Ralf Heim = RH!)

Hahaha...good point.

ebola

mozokev
11-05-2013, 23:19
Hasn't anyone bothered to look at Ralf Heim's dissertation? (Ralf Heim = RH!) OK, it is in German, but the tables are easy to read. RH-34 is a low affinity agonist at 5HT-2a receptors, about 20% that of 2C-B, so based on that it shouldn't be active until about 80-100 mg. Nevertheless, a proper titration is in order. What was interesting about RH-34, of course, is that the 2-methoxybenzyl group made an antagonist (Ketanserin) into an agonist. This led to the preparation of the N-BOMe derivatives of the 2C-Xs, and the rest is history.

Affinity does not equal active dosage, if I'm correct. Perfect example is LSD vs. NBOMe's. LSD has lower affinity for 5HT-2A receptors than NBOMe's but is more potent dose wise.

crOOk
12-05-2013, 00:30
Buying something with a cut is silly shit brother. And makes the source super not trust worthy. Sell the pure people, let Darwinism take its course.

I still bet this shit sucks.Assuming I'd buy anything with a cut is just as silly, bro! ;) (See my earlier posts)



Hasn't anyone bothered to look at Ralf Heim's dissertation? (Ralf Heim = RH!) OK, it is in German, but the tables are easy to read. RH-34 is a low affinity agonist at 5HT-2a receptors, about 20% that of 2C-B, so based on that it shouldn't be active until about 80-100 mg. Nevertheless, a proper titration is in order. What was interesting about RH-34, of course, is that the 2-methoxybenzyl group made an antagonist (Ketanserin) into an agonist. This led to the preparation of the N-BOMe derivatives of the 2C-Xs, and the rest is history.
I flew through the whole thing, reading only the parts interesting to me. Affinity alone isn't an indicator on what the substance triggers upon binding to it's target(s). It could have a very high efficacy (e.g. over 100 - triggering a stronger reaction than serotonin itself does), be neutral (antagonists have 0 efficacy) or an extremely low one (negative efficacy - Inverse agonist, triggering a reaction opposed to that triggered by the reference ligand). But you'll know all this very well, having read and comprehended the whole dissertation. ;)

tryp2fun
12-05-2013, 16:18
I flew through the whole thing, reading only the parts interesting to me. Affinity alone isn't an indicator on what the substance triggers upon binding to it's target(s). It could have a very high efficacy (e.g. over 100 - triggering a stronger reaction than serotonin itself does), be neutral (antagonists have 0 efficacy) or an extremely low one (negative efficacy - Inverse agonist, triggering a reaction opposed to that triggered by the reference ligand). But you'll know all this very well, having read and comprehended the whole dissertation. ;)

Well, since I only had one year of German in school, I obviously could not read and comprehend the whole thing. However, I do teach medicinal chemistry, so I know the difference between affinity and efficacy very well, as well as the role of pharmacokinetics and pharmacodynamics in drug action. If you look at the affinities of 2C-Xs, DOXs, and the NBOMEs, there is a clear correlation between the relative affinities at 5HT-2a receptors and the drug potency. The DOXs are about 10-fold higher affinity than 2C-xs and the NBOMes are about 20-fold higher affinity. That is pretty close to the dose ratios, since 2C-I is active at about 15-20 mg, DOI at about 1-2 mg, and 25I-NBOMe at 0.5-1 mg. Since the affinity of RH-34 at 5HT-2a receptors is lower than 2C-Xs, it is reasonable from the data above that it will be less potent than the 2C-Xs. Certainly there is no reason to expect it to be active at mcg levels just because it has a 2-methoxybenzyl substituent. The reason that the affinity of LSD at 5HT-2a receptors does not correlate as well with dose is that LSD is a very promiscuous molecule that binds to a wide range of serotonin and dopamine receptors.

crOOk
12-05-2013, 18:57
Well, since I only had one year of German in school, I obviously could not read and comprehend the whole thing. However, I do teach medicinal chemistry, so I know the difference between affinity and efficacy very well, as well as the role of pharmacokinetics and pharmacodynamics in drug action. If you look at the affinities of 2C-Xs, DOXs, and the NBOMEs, there is a clear correlation between the relative affinities at 5HT-2a receptors and the drug potency. The DOXs are about 10-fold higher affinity than 2C-xs and the NBOMes are about 20-fold higher affinity. That is pretty close to the dose ratios, since 2C-I is active at about 15-20 mg, DOI at about 1-2 mg, and 25I-NBOMe at 0.5-1 mg. Since the affinity of RH-34 at 5HT-2a receptors is lower than 2C-Xs, it is reasonable from the data above that it will be less potent than the 2C-Xs. Certainly there is no reason to expect it to be active at mcg levels just because it has a 2-methoxybenzyl substituent. The reason that the affinity of LSD at 5HT-2a receptors does not correlate as well with dose is that LSD is a very promiscuous molecule that binds to a wide range of serotonin and dopamine receptors.Yeah I forgot the whole thing is on German. That is probably why hardly "anyone bothered to look at Ralf Heim's dissertation". ;)

That aside, you are making a good point there. Nonetheless, seeing on one hand that all mentioned molecules for which the 5HT2A affinity is a very strong indicator of psychedelic activity at a given dosage are structurally very closely related phenethylamines, and on the other that the prominent exception is LSD, for which we actually do know various routes through which the psychedelic activity is facilitated that do not involve it's binding to the 5HT2Ar, I don't think your theory can reliably predict if there in fact is any psychedelic activity for a molecule that does have some affinity to 5HT2Ar's and is not closely structurally related to any known psychedelics. Not reliably enough for me not to try the stuff - Not at ug dosages but ultimately at oral and rectal dosages of 100mg (of what I assume to be uncut RH-34).

tamarinds
12-05-2013, 22:26
insert startrek.facepalm.jpeg



Too many people arleady on this planet. If some dumb fucks are reckless with chemicals and kill themselves. Fuck em, thanks for the lesson, sorry you had to pay the ultimate price. Legistlation against chrms because of deaths sucks, but the law can suck my fat raisin nuts. Fuck it.

If I happen to be one of those people oh fucking well. I use a sub milligran scale and have shit tested and titratd doses. Gonna have to be a real killer to get me.

Ordering 1000mg of supposedly very good synthed RH-34. Will send it to get tested and then will experiment, maybe. May enlist some knowledgable and willing guinea pigs. Definately will do that first. Binding profile is so weird

Solipsis
12-05-2013, 22:39
Tamarinds, you are quite entitled to your rather misanthropic opinion, but this is a Harm Reduction forum so I'm gonna have to ask you to contain yourself. ;)

Good that you're planning to employ cautionary procedures e.g. analysis and titration, let's focus on that.

tamarinds
13-05-2013, 00:16
Im in to staying alive and healthy myself. Harm Reduction I take seriously, makes IRL people mad sometimes. Losers. I dont hate humanity, some people just gotta go regardless of how or why. We killing the Earth at an amazing rate.

100ug to 250ug to 500ug to 1000ug and 500ug increments from there is what my death free research team and I where thinking of researching after the results are back; Harm Reduced.

Ill post the NMR once its ran. Bet this chem is a waste of time, gotta get to the bottom of it though :p

jesuspeople666
01-07-2013, 21:56
why would anyone call this a [fascinating chemical, when what i know is that not anyone in the world knows what it iis or haven never tried it
just the name "rh-34" sounds insane wierd, i still have my sample untouched,i dont know what to do with it

crOOk
01-07-2013, 23:02
why would anyone call this a [fascinating chemical, when what i know is that not anyone in the world knows what it iis or haven never tried it
just the name "rh-34" sounds insane wierd, i still have my sample untouched,i dont know what to do with itAt least read the 3 pages of thread, dude.

bloodshed344
02-07-2013, 02:29
why would anyone call this a [fascinating chemical, when what i know is that not anyone in the world knows what it iis or haven never tried it
just the name "rh-34" sounds insane wierd, i still have my sample untouched,i dont know what to do with it

I called it fascinating because it's fascinating. Amazing that even rustled some of yall, haha.

Honestly, how is it not fascinating? A few structure changes in the right direction and it would be even more psychedelic... there could be some cool compounds that are not really like anything humanity has seen before. and I don't necessarily mean just psychedelics.

SeenSoFar
06-07-2013, 11:12
Well, I've been curious about this one for a while, and my curiosity has finally got the better of me. I have 5 grams coming from an extremely reliable source. Will be bioassaying this one quite carefully... The possibility of agonism at lots of undesirable targets has me more than a little weary, but for some reason I cannot let this one go. I feel that there is something to it. Keep in mind I do not have a creatine-laden buffed out sample on the way, but rather the pure product. Only time will tell how this one turns out, but something tells me it's a winner. Before anyone warns me, yes, I will tread softly. I have all the right equipment and all the experience necessary to be absolutely prepared to be completely unprepared for the possible effects. ;)

By the way, I have seen some less-than-stellar sources peddling this as a cannabinoid. This is possibly how the accidental smoking mentioned earlier in the thread happened. All I can say to anyone who bought it as a cannabinoid is this: grease up the ol' corn-hole, something's coming to fuck your day!

crOOk
06-07-2013, 13:22
All I can say to anyone who bought it as a cannabinoid is this: grease up the ol' corn-hole, something's coming to fuck your day!LOL!

Unless the 10% of that creatine laden sample was something entirely different than RH-34, the stuff ain't worth shit. I removed the creatine monohydrate since it isn't water soluble unlike the alleged RH-34 salt that's contained and yielded very close to 10% of a very bitter tasting, white, water soluble crystalline substance as expected and dosed it up to 200mg rectally and orally if I remember correctly (don't take my word for it, the trials are further up in this thread) and didn't experience any psychedelic effects whatsoever. Good luck to you though, I really wanted this one to be a winner, too. Maybe it wasn't RH-34 at all what was going around, these chinese labs often have a talent for fucking up even the easiest synthesis.

tamarinds
08-07-2013, 13:24
I am waiting on a third party NMR confirmed sample to arrive. We will see what this RH-34 has hidden. I dont trust the trials posted here. Crook said it himself maybe it wasnt even rh-34.

Dun nun dun dun nun dun dun dun

SeenSoFar
10-07-2013, 06:12
Excellent! I will have my sample in two days, although who knows when I'll get a chance to assay it. I am very interested in your results. If I may make a recommendation, if oral and rectal ROAs do not produce results, would you consider vapourizing and/or insufflation? Considering that the positive reports I have encountered were all by these two ROAs, I think it's possible that it may not be active orally or rectally. Perhaps there is some condition in the digestive tract that breaks down this particular compound. My assay plan will be to do a dermal allergy test, then start with sub-milligram doses orally. If I reach ~200mg with no alert, I will try buccally/sublingually. If there's still no alert, I will move on to insufflation at the submilligram level. If again I encounter no activity, I will try to vapourize, again starting with submilligram levels. I think that will give us a pretty good idea of what this compound has to offer, if anything.

If this one does turn out to be active, even in a mediocre way, I will be extremely excited, since it will provide a jump-off point for many new compounds (QiHKAL?). You know, when you look at the ring structure, I can see at least one parallel to an indole ring, the nitrogen that is immediadely ajacent to the benzene ring is in the same position in both ring systems. It's not much, but it gives me a fools hope!

SeenSoFar
12-07-2013, 06:07
Well my sample arrived today. White, fine powder with a VERY unusual odour. Not like the typical weird smelling compounds, this is seriously not like anything I've smelled before. I can't describe it because I have no point of comparison, but when I smelled it I had a very odd feeling soon after that subsided after a few minutes. The feeling was almost like the first alert at the beginning of a psychedelic experience. It manifested as a feeling of electricity up and down my spine. This was most likely just anticipation, but I figured it was worth noting.

I have not examined it too closely, but the powder appears to be very fine without any signs of crystals. Some of it seems to have clumped together into small chunks, but for the most part it is very compact fine powder. I don't know when I will get a chance to assay it, but I am VERY excited. I don't know why, but this has become close to a crusade for me. I just have such a strong feeling about this compound, and I am just hoping that the negative reports that have come around so far are not a foreshadowing of what is to come for me...

psood0nym
12-07-2013, 07:58
I don't know why, but this has become close to a crucade for me. I just have such a strong feeling about this compound, and I am just hoping that the negative reports that have come around so far are not a foreshadowing of what is to come for me...


http://upload.wikimedia.org/wikipedia/commons/thumb/2/23/CrusaderAtrocitiesBibliothequeNationaleDeFrance.jp g/800px-CrusaderAtrocitiesBibliothequeNationaleDeFrance.jp g

Commit as many human atrocities as you need to to find out if this "RH-34" is legit. Or, and this is only if you're feeling up to the task, upload a photo of it, perform analytical tests, etc.

SeenSoFar
12-07-2013, 08:22
Hmm... Atrocities... Photography... *makes a gesture reminiscent of a pendulum balance* Well... My camera is all the way in the other room... My BROADSWORD on the other hand is right beside me!

In all seriousness though, I will post some photos of the substance, and it's reaction to marquis and mandelin reagents (I've run out of the others) over the next couple days. My camera has decided to go pear-shaped on me, so I will have to do some repairs, and once I do I will get some photos going. I am also going to look into sending some of this for analysis. I will keep you all posted!

EDIT: Unless anyone has any better ideas, I think I will be submitting a sample of this to EcstacyData.org for analysis. Who knows if they'll be able to give me a positive identification, but at least they will provide the GC/MS output if they cannot identify it. This seems to be the best option I have available at the moment, since I no longer have local access to analytical instruments. What are people's thoughts on this idea?

ebola?
12-07-2013, 08:50
http://upload.wikimedia.org/wikipedia/commons/thumb/2/23/CrusaderAtrocitiesBibliothequeNationaleDeFrance.jp g/800px-CrusaderAtrocitiesBibliothequeNationaleDeFrance.jp g

Commit as many human atrocities as you need to to find out if this "RH-34" is legit. Or, and this is only if you're feeling up to the task, upload a photo of it, perform analytical tests, etc.

Hahahahahah....

ebola

bob_arctor
12-07-2013, 17:09
From the EU Early Warning System:


In Frankreich wurden mit RH-34 und 2-(2,3-dimethoxyphenyl)-N-(3,4,5-trimethoxybenzyl)ethanamine zwei neue psychoaktive Substanzen identifiziert:

3-[2-(2-methoxybenzylamino)ethyl]-1H-quinazoline-2,4-dione (RH-34) is a quinazoline which contains a N-2-methoxybenzyl structure (-NBOMe). It has been predicted to be a potent and selective partial agonist for the 5-HT2A serotonin receptor according to computational studies (Silva et al. 2011).
Silva ME, Heim R, Strasser A, Elz S, Dove S (January 2011). "Theoretical studies on the interaction of partial agonists with the 5-HT(2A) receptor". Journal of Computer-aided Molecular Design 25 (1): 51–66.
2-(2,3-dimethoxyphenyl)-N-(3,4,5-trimethoxybenzyl)ethanamine is a substituted phenethylamine which shares some similarities with NBOMe-like structures.

The French FP has reported seizures of white powder of both substances seized at Brest, in April 2013. The circumstances of the seizure involved indications of small scale trafficking and illicit production. A young person was found in the street, in a confused state; the person had a lab where these and other substances were found (25-H-NBOMe, 25-I-NBOMe, UR-144, 25-C-NBOMe and kratom).

SeenSoFar
13-10-2013, 11:56
Well, after lots of precautions, I finally got what seems to be the beginning of promising results with this compound. 1mg vapourized resulted in some threshold effects. After dripping 4 250 microgram drops onto foil I vapourized the resulting solution and took the water and chemical vapour in one inhalation. I held the vapour for about 30 seconds before exhaling. Upon exhalation I noticed a mild head rush and some sparkling of my vision which did not fade with the passing seconds. I noticed a mild shift towards orange in the colours around me, and things appeared to have acquired a slight vibration. Pulse was elevated to 100BPM from a normal rest rate of 80BPM. Blood pressure was not checked. Pupils were enlarged noticeably. Gait was normal, no loss of coordination or balance. In the body I noticed a feeling of lightness and slight paresthesia that seemed to migrate around my flesh. I felt very relaxed, and my thought processes were slightly altered, with a slight acceleration and increase in free-associative thinking. The effects seemed to build slightly over the first 2-3 minutes, and then were steady for 3-4 hours before dropping off to a feeling of contentment and extreme hunger. By extreme, I mean extreme, like weed munchies don't touch this, I was eating condiments. All in all, very interesting. I'm looking forward to going higher.