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Opioids oxycontin oral to iv?

vfoolio

Greenlighter
Joined
Dec 18, 2009
Messages
15
hey

im just wondering if it takes me around 25mg of oc intranasal to get me to where i want to be. how much would this equate to if administered via IV?
 
Well, the numbers vary a bit for intranasal bioavailability but for the sake of the discussion we'll assume it's ~50%. IV bioavailability is going to be 100%, so your dosage should be cut in half at the very least, but you should start with a much smaller dosage than you think you can handle anyway, so it should be even lower than that. ;p

In my opinion oxycodone is best taken orally, it has a much higher bioavailability (~80% ) compared to intranasal, not to mention you get to avoid snorting a ton of fillers and binders into your extremely sensitive nasal passages. Of course plugging is a viable option as well,

Speaking of fillers and binders, if you're going to be injecting pills you should really be using a micron filter.

It's not worth the risk, otherwise.
 
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