Technically the short answer is no. Anything over 400mg of Tramadol at once is considered to be not safe. I took Tramadol almost daily for a year and was up to 3-4 grams per day, if not more. The one night I took 600mg, laid down, and almost chewed my tongue off from a gran mal seizure.
Is the seizure risk really that severe in doses over 400 mg's?What if someone has been on it for a long time,does tolerance develop to this effect?
I know this is a harm reduction place and everyone is just making sure everyone is safe,but I (from my own use with tramadol which is quite a bit actually)find the 400 mg seizure thing to be quite exaggerrated,though I'd still advise people to take it easy and never take massive doses over 400 milligrams.