Hi all!
I recently came into an amount of orphenadrine, enough to mess around with. I honestly didn't know anything about it until I ended up with it, and I must say is a rather curious antihistamine.
For some back story, I have a large amount of experience with antihistamines, being a chronic eczema and asthma sufferer, as well as a routine codeine abuser. I've never had an antihistamine with such pronounced muscle relaxant effects, its a very very curious drug.
Now, I've currently been taking it in doses of 105mg, and it's almost too much for me! The insomnia that I've heard of is indeed present, and I'm normally rather immune to such effects in other drugs: it makes sleeping almost uncomfortable, which is where the somnolence seems to stem from.
I've combined it with a large dose of codeine (approx. 300mg) once, but because I'd used 105mg of orphenadrine it seemed to entirely overpower it!
I am going to experiment with a smaller dose, 70mg, to observe the effects. Was wondering if anyone would be at all interested in a "trip" report? Simply because there seems to be a startling lack of info around about this curious antihistamine: it gets mentioned a lot, but discussed very little.
Now, if you were to take it to potentiate Codeine, I wonder what the best dosing schedule would be? I'll report back later with an exact timing of effects, it might make it a little bit easier to answer that question I'd wager.
Of note, smoking severely lessens the effects of it, I believe because the nicotine working in direct opposition to the orphenadrine on your Muscarinic receptors (from memory).
Now, according to the ever reliable 8) Wiki, it used to be abused for "euphoria". I'm yet to experience that, but every time I've taken it it seems... well, enjoyable heh.
Also as a note, it's excreted through bile, and seems to flare up my gastro-oesophageal reflux disorder, which is somewhat of a pain but nothing out of the ordinary for me.
Thoughts? Links? Info? Cheers!
I recently came into an amount of orphenadrine, enough to mess around with. I honestly didn't know anything about it until I ended up with it, and I must say is a rather curious antihistamine.
For some back story, I have a large amount of experience with antihistamines, being a chronic eczema and asthma sufferer, as well as a routine codeine abuser. I've never had an antihistamine with such pronounced muscle relaxant effects, its a very very curious drug.
Now, I've currently been taking it in doses of 105mg, and it's almost too much for me! The insomnia that I've heard of is indeed present, and I'm normally rather immune to such effects in other drugs: it makes sleeping almost uncomfortable, which is where the somnolence seems to stem from.
I've combined it with a large dose of codeine (approx. 300mg) once, but because I'd used 105mg of orphenadrine it seemed to entirely overpower it!
I am going to experiment with a smaller dose, 70mg, to observe the effects. Was wondering if anyone would be at all interested in a "trip" report? Simply because there seems to be a startling lack of info around about this curious antihistamine: it gets mentioned a lot, but discussed very little.
Now, if you were to take it to potentiate Codeine, I wonder what the best dosing schedule would be? I'll report back later with an exact timing of effects, it might make it a little bit easier to answer that question I'd wager.
Of note, smoking severely lessens the effects of it, I believe because the nicotine working in direct opposition to the orphenadrine on your Muscarinic receptors (from memory).
Now, according to the ever reliable 8) Wiki, it used to be abused for "euphoria". I'm yet to experience that, but every time I've taken it it seems... well, enjoyable heh.
Also as a note, it's excreted through bile, and seems to flare up my gastro-oesophageal reflux disorder, which is somewhat of a pain but nothing out of the ordinary for me.
Thoughts? Links? Info? Cheers!
