View Full Version : (opioids) cure for restless legs from opiate withdrawal?

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12-09-2010, 06:50
^ that is meant for restless legs syndrome but im not sure it pertains to opiate w/d's since they're more severe than regular restless legs..
i didn't read the whole thread and everyones responses but my advice is..
-clonidine & vistaril/atarax (these help, but only take vistaril or atarax if you have clonidine also because they are antihistamines and have a chance they could make them a little worse but they are calming/ relaxing and will help you get some sleep especially combined with clonidine)
-BENZOS i recommend clonazepam for during the day and temazepam for sleep but everyone has their preferences but benzos help tremendously
- And of course the obvious.. more opiates (but if you're in w/d you are either A) quitting or B) can't get any).. so this might not help..
- Also tramadol and Immodium can help too.

12-09-2010, 23:24
Tie Bed sheet off on each leg. Or something to cut off the circulation. Thats some jail house no other option stuff though.

13-09-2010, 08:51
tie bed sheet off on each leg. Or something to cut off the circulation. Thats some jail house no other option stuff though.

wow! Do not do this!!

13-09-2010, 13:22
i suggest lyrica. stuff is a fucking panacea.

13-09-2010, 14:02
since you cross posted this at Shroomery I can't be bothered to answer twice. Read that one, I didn't waste a half an hour giving you my best advice to have to do it twice.

13-09-2010, 14:10

13-09-2010, 15:21
^ that is meant for restless legs syndrome but im not sure it pertains to opiate w/d's since they're more severe than regular restless legs.....

Actually its not only meant for "regular" restless leg syndrome its actually prescribed for people with parkinsons disease who are the people with some of the most restless bodies on earth. I have a bottle of 0.5 mg mirapex and when I take even just one pill, maybe one and a half, and im in withdrawal, it will not only take care of my RLS 100%, it will knock me the fuck out. Especially if I take 2 or more pills(which I pretty much never have to do, and I don't ever remember taking more than 2 pills).

Mirapex works better for opiate related RLS than anything else I have tried(other than more opiates) and I have tried ALOT of shit, including valerian root, propranolol, OTC sleep aids, etc....

I also reccomend a high dose of any benzo(especially the hypnotic ones....temzepam, triazolam, etc...). Or whatever dose will help knock you out, cause when your asleep you dont notice any RLS.

13-09-2010, 22:21
oh man...i hate rls...got it REAL bad a few times. like most other posters said, a hot bath does seem to work, i didnt take any otc meds or anything...i took a few muscle relaxers...im not really sure what they were. haha i really didnt care at the time! but anyway the muscle relaxers didnt seem to help at all. i think it may have gotten worse. well good luck to ya bro. my legs are hurtin just thinkin bout this shit!

25-01-2011, 23:11
All good suggestions. All I can say is alcohol can go both ways.


Work well at first then bad later, hit or miss.

25-01-2011, 23:45

No. Don't use diphenhydramine for RLS. It makes it considerably worse.

26-01-2011, 03:09
I can SO sympathize with you. Have been there many many times. I have to agree with mostly e everyone here when they say benzos or I have been trying ativan _ I still think the Xanax Work better. I guess it depends on what your drug of choice is. I can tell you all this the next time that I feel that the with drawls are coming I will turn to tjr wonderful people I have met.

26-01-2011, 08:48
As far as the question about Requip goes here is my experience...

When I first got addicted to OPs, I started getting RLS every night when I went to bed. I HAD NO IDEA it was due to the opiates so I tried everything. Finally went to my doctor for it, who prescribed me Requip.

About a month later I put 2 and 2 together and have had some of the most hellish nights on earth since then (Im currently at 400+/mg per day injected habit of OC)

not IME at least.... ive taken lots, ive take a little... it didnt do shit

Loperamide helps a BIT, but nothing to sneeze at
Kratom is a gift from god

otherwise your gonna either end up copping, or your in for a week or more of pure HELL


26-01-2011, 14:00
gbl works for me

26-01-2011, 14:01
IME, hundreds of mgs of diazepam.

26-01-2011, 14:22
And what should do a person who's heavily addicted to benzodiazepines and loperamide doesn't do a thing because it doesn't cross BBB (that means it does in such quantity, it doesn't have a central effect at all)? I'm such a person. In my case restless legs caused by opioid withdrawal can be helped only an opioid can help. Otherwise, one should proceed with drugs normally used for restless leg syndrome, i.e. certain dopamine agonists (most selective for D3), benzodiazepines (and SOME other anticonvulsants), and opioids as a last resort (well, it's no surprise if restless legs are symptoms during both benzodiazepine and opioid withdrawals).

Antihistamines often used to augment opioid effects are contradicted here as well as antidepressants (serotonin flood doesn't help so it concerns old TCAs and SSRIs/SNRIs), neuroleptics (they cause restless legs themselves, I've even experienced it taking steady dose of methadone and a few antipsychotics).

27-01-2011, 00:16
Ohh man, this is by far the worste symptom I feel when W/Ding, I get it so bad and not just my legs but in the arms too, especially my left arm. Not too many thing really help it too so I basically just don't get any sleep for about 5-7 days, I absolutely cannot sleep when this goes on so I just grin and bear it, especially in a detox facility, man it sucks. Anyways I have foudn that even benzos like xanax really dont do the job, however the one thing that cuts out about 90% of it is Librium, that helps so much and does wonders for me when laying in bed and trying to sleep. I still get a slight twitch but nothing I cannot deal with. I would for sure recommend Librium to you. Good Luck!

27-01-2011, 16:53
for the restless legs you should try Chinin" (thats what its calles here in germany) ,i think quinine in english (correct me if i`m wrong) , heard it works wonders with muscle cramps and restless legs at a dose of 200-400mg/day....here it comes in very cheap packages of 20pills with 200mg each without prescription.....

27-01-2011, 16:55
an oxy junky friend of mine, found that playing video games and smoking hash helped him get through oxy WDs.

15-03-2011, 03:06
i am a huge opiate addict. my wd r terrible as im sure everyone elses r. if i could get past the leg thing i might have a chance. what is this stuff about immodium bein a opiate? if thats true will it make me feel better and take withdrawal away????????????? HELP. i think im losin it peeps!

15-03-2011, 03:15
gabapentin and maybe ketamine for restless legs

15-03-2011, 18:42
is this true about the imodium, that its good for withdrawl

15-03-2011, 18:55

15-03-2011, 20:23
Rx: Zolpidem (ambien)

OTC: doxylamine ("unisom II") + smoke a little weed

'medicine cabinet'
15-03-2011, 21:18
wow! Do not do this!!

yea i hate to say it but it does work even though it's never a good idea to cut off circulation to your extremities. When i was at inpatient rehab they only gave out trazadone and i wouldnt take it because it made me feel even worse. I would get such bad RLS that i would tie the bed sheet around my ankle to try and stop the pain, it was literally the only thing i could do to get even a small bit of relief. and yea that is something you would do when you dont have access to meds like in prison or a cut rate rehab...

now if you do have access to drugs or a dr willing to rx something to help you, i would go for clonidine. it really does help with RLS and its not addictive like benzos, or scheduled like lyrica so it is pretty easy to get.

16-03-2011, 03:12
Seconal, or any other barb. And alot of weed.

16-03-2011, 03:49

mr. mudd
17-03-2011, 18:53
I find that my RLS gets so bad in withdrawal that even bezoes (temazepam, lorazepam, clonazepam) exacerbate it--normally they work great for RLS, but when I'm in full withdrawal I get a paradoxical reaction to them. Clonidine makes it worse too, as does benadryl, seraquil, zopiclone, etc. I haven't tried the dopamine agonists but I've read they can create rebound. I've had RLS my whole life (except when clean and jogging) so when in w/d it's really severe.

In full withdrawal I have only ever found two things to help:

-a hot bath with some epsom salts (magnesium sulfate), though this is TEMPORARY relief only; my jimmy legs return after about half an hour

-barbituates, which I cannot obtain anymore as my (more liberal) doctor retired (and they are non-existent on the black market in my area of Canada, as far as I know)

I've never tried gabapentin, so I can't comment on that.

19-03-2011, 02:06
once i took a bunch of seroquill in highschool one night when i was drinking .

instead of getting any sort of recreational effect; i got the most horrendous RLS i have ever experienced.

i was kicking and writhing around for hours wondering what the fuck was wrong and seriously hoping i hadn't somehow given myself RLS and this feeling would be permanent.

luckily it was a one night thing, but i would expect seroquill to really fuck with some one in WDs

27-05-2011, 21:50
ONE. Find something you really used to enjoy before your OP addiction and attempt to lose yourself in it, reflect on what an a$$hole u have probably turned yourself into (depending on how severe we are).

TWO. Repeat ONE while forever having thick clouds of weed smoke coming out from within the deepest depths of your lungs. And yes, non-stop until ur out, (weed is a natural muscle relaxent, so says science, which got us all to this thread in the first place)

This along with anything else won't truely keep you off, as ANYTHING and EVERYTHING is only a temporary solution. Get the will power, I did.

27-05-2011, 22:47
why would you suggest another opiate for this person who wants to quit. potassium supplement worked for some extent for me. take my words with a grain however. most things that work for me dont work for others. call it placebo or whatever. a mild benzo such as lorazepam or even better clonazepam. from experience with alprazolam it really sucks during op wd

Some pretty decent advice on the potassium...although for most people magnesium oxide (MagOx) works better to deal with nervous muscle issues. A potassium/magnesium blend I found worked the best for me.
The poster who suggested Tylenol #1 is probably assuming that the OP has some significant tolerance issues, and that low dose codeine would greatly alleviate his RLS (and other WD symptoms, too). It could also provide the ability to taper. Also, if you're going to use benzos I would suggest diazepam (Valium) due to its inherent muscle relaxing properties.

27-05-2011, 23:04
i suggest lyrica. stuff is a fucking panacea.

Lyrica is also a decent suggestion (although IMO nothing beats Valium). The hot bath thing helped immensely for me too. I would not suggest using any dopamine agonists (Mirapex and the like) for opiate WD's though. There are better things, they can be quite dangerous if not used properly, and they also stimulate twitches & tics in certain individuals.

27-05-2011, 23:19
dude i feel for you. this is why they call it "kicking the habit". My dad is a physician and carefully and scarcely dosed me with .5-1mg alprazolam the first few times i went through serious withdrawals around 2 years older than you are now. the previous poster was correct about the doc reccomending rehab. maybe you should consider it if your serious, but the problem im facing currently is that there is no rehab that allows semi-abstinence. if you are anything like me at 16 then you probably just want to be a normal kid and have a normal few remaining years of highschool, then be able to drink and party like normal in college. if your're a true addict this is going to be so much tougher than you realize. your addiction will manifest in many ways, not just through drugs but through relationships, sex, tv, video games, interenet, etc. I dunno i wish i could go back to where you are now and make different choices. Im in my last year of undergrad at a state university studying accounting and I would be graduating this month if it werent for my 4 month stint of inpatient rehab I needed to get off H. even then I went back to it. You can read from my other recent posts im still in a dangerous zone. I took measures that suck but will likely save my life. ive moved back in with my parents, given up any money I had, stopped contact with many of my using buddies (although i was much more an isolated user) The restless legs will go away faster than you realize and they too are much more a mental phenomenon rather than biological. benzos really will help but be careeeefullllll

28-05-2011, 03:48
I think the consensus is basically as follows: barbituates and benzodiazepines are the BEST things for RLS (after of course actual opiate agonists) - I think that they are so effective because they reduce anxiety and irritation as well, so you don't reflect as much on your restlessness and the nature of your situation, although they are of course also muscle relaxants and as such do help your legs; after that immodium (loperamide) and naproxen and OTC type stuff; after that stretches, baths and distractions.

When this happened to me I had no access to benzos or barbs and could not even take immodium as I was on bupe and had heard bad things about ineffectiveness and precipitated withdrawal; I just took seroquel and that eventually put me out.

If you can't get the better stuff, there are lots of antihistamines sold OTC that induce fatigue - one is called I think 'diphenhydramine' or something like that.


28-05-2011, 13:13
Kratom helped me... RLS was the fucking worst part of WD's and I always gave in and relapsed because of it... Until last time. I took kratom every time I started getting RLS and it went away, I was still withdrawling, but without the RLS it made things SO much easier, especially since you can get sleep. I know kratom and opiates kinda have a cross tolerance, but you can do a quick taper on that as well as the original WD symptoms lessen.

I know people think kratom is bullshit, but I owe it my life.

29-05-2011, 00:07
I'm using kratom to get off of my subs and was thinking about using a kava extract to help with the anxiety and RLS. I have used regular kava but I definitely wouldn't be able to choke down a cup of that shit without throwing it back up. Has anyone used kava with success for this? I basically just want an extract so that I can fill a couple of capsules and just swallow them

16-03-2012, 10:18
it is LACK of dopamine that causes RLS imo so taking anti psychotics, various antihistamines and nausea drugs (most are technically an anti psychotic) will make it worse.

18-03-2012, 15:52
Clonidine or tizanidine help. An alpha2 adrenoreceptor agonist is a good idea to help prevent the sypathetic storm coming from opioid withdrawal.

MXE works GREAT for tapering...it might have opioid activitiy of its own, it suppresses withdrawals, and stamps down on tolerance. Best used IV in small doses whenever withdrawals become too much, after a couple of days worth of attack dosing.

Magnesium oxide is not very bioavailable, chelated forms are best. Magnesium glycinate might be an idea. Glycine seems to potentiate NMDA receptors..but it has inhibitory effects of its own through strychnine sensitive GLyRs. Benzos never worked very well for the RLS from opioid withdrawal. Alpha2 adrenoreceptor agonists, are the best for this, absolute fucking fantastic stuff, tizanidine is, or clonidine. They use another one here in the UK as opioid withdrawal therapy, lofexidine aka britlofex.

Lyrica is another good bet as has been said...gabapentin would do the same thing.

19-03-2012, 03:57

14-04-2013, 05:37
The question is how long did you take the Suboxone because I know If I take 2 mg of Suboxone 24 hours after my last dose then I take 2 mg four hours after I feel better then every other day for seven days I take 1 mg of Suboxone and then I am fine and I was kicking a good 180mg a day OxyContin habit, not snorting though

14-04-2013, 05:50
pregabalin is probably pretty good as well.

24-04-2013, 14:05
I agree gabapentin and lyrica work wonders. But u have to take way more than usual. I had taken a dose of about 3gr and ended up in the er I couldn't form my words and could barely walk. I knew what I had wanted to say but it just came out wrong almost like a stroke victim but all my labs were good. They didn't know I was in w/d though I'm sure they would have acted differently.

I had been taken gabapentin and pregabalin (when I had insurance) for quite a while off and on too. So just fair warning some people do have adverse effects.

Now I have been on a methadone rx for cp for about 4 months along with xanax and of course od'd when I first started my husband saved me by CPR thank god he is attentive to every noise and heard the change in my breathing. So there i go to the hospital for the 2nd time.

Now after all of this I finally had enough and stopped the done cold turkey at a "prescribed" 10mg 4/day

Two days later I have a seizure and I had been taking the forbidden gabapentin which I had a secret script for. Was it from the methadone or GABA not sure.

I'm still going strong though. Day 8 w/d finally fully kicked in. The anxiety and rls are the worst. My dr finally prescribed me some xanax and muscle relaxers on day 12. Now I am on day 13 and I wrapped my legs with ace wrap to sleep put my arm braces on and I slept all night. Oh yeah I took two xanax before bed. Hopefully things are going up from here. Just tired no energy to be expected and pain.

I have tried kratom too and it never worked. I got the speedy effects every time.

13-05-2013, 22:33
So, RLS is my absolute worst symptom in WD. I have tryed Lyrica 75mg and get some relief and I take clonzapam which helps me sleep a little. The lyrica worked a little as well, do I have to take more that 75 mg? I also use a TENS machine which can help if you can keep the electrodes stuck to your legs without kicking them off. I have some Mirapex and Requip on the way to try. I also have tried the gabaptin or gaba and no luck. I have not tried the clondine.

I guess from what I'm learning is that I have a very severe case of RLS or just one leg kicking. I cant seem to find anything to stop it and right now its the only thing stopping me from making it off opiates. Anything else I can try folks? Other than more opiates of course.

14-05-2013, 06:36
So, RLS is my absolute worst symptom in WD. I have tryed Lyrica 75mg and get some relief and I take clonzapam which helps me sleep a little. The lyrica worked a little as well, do I have to take more that 75 mg? I also use a TENS machine which can help if you can keep the electrodes stuck to your legs without kicking them off. I have some Mirapex and Requip on the way to try. I also have tried the gabaptin or gaba and no luck. I have not tried the clondine.

I guess from what I'm learning is that I have a very severe case of RLS or just one leg kicking. I cant seem to find anything to stop it and right now its the only thing stopping me from making it off opiates. Anything else I can try folks? Other than more opiates of course.

Try at least 150mg of lyrica and get some clonidine, do not mix these with benzos or you will most likely die due to respiratory depression (this is no joke benzos and lyrica cannot be used together safely), use one or the other.

Also get 2kg of epsom salts and pour them in a hot bath, lie in there for as long as possible.

14-05-2013, 21:34
What does Clonidine due exactly, just lower your bp? Why does Lyrica help with the RLS? Are you saying you can mix clonidine with the lyrica, just not with benzos right?

I have an extreme rls and the longest I've ever been able to put up with it has been a week. Any ideas on what the average time it lasts? I have friends that have come off much higher doses of opiates than me and only have full body shakes once or twice, but with me its every night and just my left leg, so strange. Guess I just got lucky. I did know that the baths help me quite a bit for sure, anything else you can think of off the top of your head?

16-05-2013, 09:41
I have not heard of lyrica working to any real extent... the only really effective treatment (aside from taking enough benzos to knock out all muscle response) is using a dopamine agonist (Mirapex or requip or similar)... of course these come with their own issues and really only provide enough of a Band-Aid to hep until (hopefully) your body resolves the problem on its own... when I quit I had RLS for 40 days... just as the above poster said it was the only thing that made me seriously consider the possibility of using again.. thank god I got through it...

oh and bananas... I started eating a banana every day at like 35 days and by day 40 it was gone... I have no idea if that was the deciding factor...

22-05-2013, 03:02
I have the mirapex and requip to try but I'm honestly scared to death. I think I have actually broken my toe several times!!! I think maybe why the banana helped was the potassium it gave you, but I certainly don't think I can take 30 days of RLS that would be awful, how did you deal with that did you just not sleep? I never had the RLS until I had a car accident and was given tramadol which I later found out is like an ssri but I haven't taken those for awhile. My doctor has not seen anything like it before and had me on traditional opiates and now I'm doing a 12 day taper, tomorrow being the last day. Honestly, I don't think there is anyway around this stuff I'm just going to have to go through the RLS unless the mirapex/requip works. Man opiates are good and bad, such a slippery slope. Thanks for the reply, if anyone else has found anything that stopped RLS for them I would love to hear about your story.

26-05-2013, 10:59
kava may help more than alot of perscriptions.

27-05-2013, 03:14
bananas and/or potassium suppliments help, tradtional restlegs can be caused by a lack of magnesium, so find foods rich with magnesium, they have better absorbtion than magnesium pills, also hylands restless legs work decently, they dont cure it %100, but it can make it tolerable, it's available otc pretty much anywhere in the US ( walgreens, walmart)..

27-05-2013, 04:09
Clonidine works wonders & personally made me sleep like a rock. You have to be careful with how much of that you take as well because it really drops your BP. In a big way. If you can get ahold of some benzos they worked wonders for rls, they prescribe klonopin /clonazepam for rls around here. & no shit, bananas & broccoli for potassium kick ass.

27-05-2013, 04:14
The motha fuckin cure is do more drugs/alc