I'm bipolar and a neuroscience post grad so nobody come at me for mixing its my mind.
Trip regually ish once a year or so. Anyway. Orlanzapine 2.5mg and lamotrogine 25mg do not block effects of 300ug. In my experience, higher doses would need to be monitored closely. Visuals may not be as pronounced but mood and exploring the mind good to go.
Lamotrogine larger doses probably also won't effect trips, in my experience. Orlanzapine can also take the anxiety off.
Use with caution always at your own risk stay at smaller does.