I firmly believe that once the doors of investigation and genuine scientific enquiry in these areas are flung open, whereas they are currently held closed by the insane drug laws of the world.
Once this happens, I thin we'll see an explosion of research into mild-altering compounds, especially psychedelics as they have a head start somewhat in terms of having a strong overlap between psychedelic researchers and psychedelic fans.
Moving being the one chemical model, perhaps we can come up with novel ways to produce intoxicated stated with a multi-pronged approach, firstly:
1) Intelligent planning and study in polydrug use opens a number of doors, which combinations are more than the sum of the parts - which compounds produce unpredicted and desirable effects (cue, toxicity evaluation and further study)- what effect does timing have on the experience.
2) We may be on the custp of some kind of true, high bandwidth, brain computer interface becoming available in our lifetimes. If this is the case we have another method entirely of manipulating our experiential landscape. Elon Musks "Neurolink" presentation had a brief segment at the end with a billboard and a lit of facets of our being which could be anylysed and manipulated - one of them being "mood"... The guy talking at the didn't dwell, perhaps anticipating all the dumb questions and irrelevant backlash (irrelevant for the foreseeable future anyway.
3) Technology may improve the drug landscape in other ways. Targeting, programmed nano-machines or nano-delivery devices might systematically stimulate one of more brain regions, or realise 1 or more substances in low calibrated doses at finely tuned intervals. The computers that produce the drugs themselves will advance too = already we take a somewhat brute force, computer assisted method to iterate through a list of imaginary compounds, quick ran basis in vitro experiences, and process from there. The medical computers of the future will be far more advanced if we turn deep learning algorithms on the entirely library of human knowledge of psychopharmacology, who knows what they'd come up with....
So in summary, I don't believe we have explored every nook and crannie of our psychoscape. For sure, every now and then a substance appears that is something of an archetype within it's class, and it's possible (though not guranteed) that the classes we assign as, in actual fact, a good reflection of our internal word, so while all drugs have their character, there may not be anything TRULY unique, as it, possessing an experience that is neither psychedelic, dissociative, stimulating, depressing, or whatever other category of subjective drug effects you can think of. But what should be possible is to fine tune what we already have.
Look closer, get to the root of the damaging and harmful side effects. Edit with the aim to remove. I invite you to envision some miracle drug in the form of a small robot pellet which is actually a very small AI controlled drug delivery system. The calculated contents and timings are designed to give you a feeling of transcendental beauty of the world - when you relax - you will trip hard. When something serious happens, your brain miraculously clears up, you feel like you're on meth, but if you ever had a bad experience, this is not this. You feel amazing and fully capable of tackling this previously annoying thing you had to deal with. Overlaying this, over your entire day you're just open, serene, and connected to people. You may as well be on MDMA, your emotions are so free... but the physical side effects are just nonexistent - gone. Your heart rate is normal, your're not sweating loads, and you can have a beautiful, open conversation with someone, with anyone! Without rolling your eyes back into your head every 5 minutes and also without weirding them out - and not because they're on this too - although they are, because why wouldn't they be? Miracles like this are prescribed to everyone in our utopia. :giggle:
You have to do some work stuff - invoke Meth Mode again, plain old dextroamphetmaine, maybe just modifinal - just whatever stimulant drug can make you focus like a machine, But you don't forget to eat, you could sleep if you wanted, these side effects are either removed or effectively blocked entirely by the "smart drug" delivery system.
Say you have a date later with someone you've only seen a few times before. You're not nervous in the slightest, just excited, and determined that it does well. For nervoursness, especially socially in our relatively safe, highly advanced towns and cities, is just not desired or needed in this instead. You head to the date and it does indeed go well, you're both connecting like horny wildfire - this is a drunk date, to some extent, but neither of you are drunk. Quite the opposite. You are both lucid and clear, and most definitely unimpaired. You discuss the quirks and nuances of your own more surface aspects of your Daily Dose (TM), ie, trips when sitting down, a sparkly effect visible on moth flats surfaces. These are state issues medicines to correct the inbuilt human pains of being alive, not everyone is the same, not everyone's brain is the same, and some people may setting on custom formulae after discussing it with their doctor.
Anyway, the date goes well, as most do now between fundamentally nice, polite and compassionate people - and even between people who fit none of those descriptions - because unencumbered by nervousness, stress, depression, anxiety and all the wonderful quirks of being a human being, people are true FREE to be who the desire themselves to be, and to present themselves openly and honestly to all others. This is itself means that more people end up with more friends, more easily, more gets done because of the spirit of almost boundless altruism and desire to pursue a goal, a desire upgraded from a mere suggestion in the past as a way to find passions for living, to something actually induced, encoding by external factors. People are interesting and almost everyone has fascinating story to tell if you can out of yourself enough just to see it. Most dates do go well in this world - everyone has an incredible story about just being alive, and the more people realise this, on both sides of the conversation, I believe the more compassionate and forgiving we'll be... Even if it does fizzle out later, of course they are far fewer hard feelings - explosive endings are just vanishing rare.
The day ends, and detecting your circadian cycle twitching, because slow release of stuff to make you sleep deeper, better, nicer. You wake up feeling genuinely create, youir body and your implanted drug delivery system having started to bleed essential vitamins into you as it detect's you are close to waking, as well as the archetypal, top of the range "morning drug". However it didn't really need to do that. You would have woken up feeling great anyway - you've been in this 24/7 mind-augmentation medicine for a few years now, and the neural pathways and habits of thought are so encoded thata few days break, a week, months or more, will not do significant harm. The smart drug module cleans up after itself, and the drugs used were cutting edge adaptations of earlier substances, redesigned entirely with over vital caveat - they CANNOT have a destabilitizing effect on the min, They must take nothing but sadness and leave only traces.
May have meandered a bit of topic there. But in sum I think it's totally possible that there will be substances in future that would given us access to a facet of consciousness that we just don't even know about now. The scenario I described was focusing on the healthcare system in this future Substance-aware, Substance-friendy version of the future days of human kind. So this is in the corporate setting. Just imagine what would be going on on the recreational labs!
