Why does bioavailability differ between different ROA
Per the usual, I get a little high, and then I think about stuff and come across questions that peak my interest and after a failed google search I come here for the answer. Now this may be a stupid question, I don?t think it is but why is it that say ocycodone has a lower a absorption, or bioavailability, when snorted then when swallowed or plugged. Like if ocycodone is water soluble and so can completely absorb through the nasal cavity why is the BA lower? Does it have something to do with like the way it?s metabolized or something else?
Per the usual, I get a little high, and then I think about stuff and come across questions that peak my interest and after a failed google search I come here for the answer. Now this may be a stupid question, I don?t think it is but why is it that say ocycodone has a lower a absorption, or bioavailability, when snorted then when swallowed or plugged. Like if ocycodone is water soluble and so can completely absorb through the nasal cavity why is the BA lower? Does it have something to do with like the way it?s metabolized or something else?
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