Depends what you wanted out of it. If the rush was your main goal then yes you would be missing out by not vaping. But I think the overall effects were much better by other roa , vaping would almost always result in doing way too much way too fast and then your too paranoid and side effect ridden to really enjoy it. It's hard to fap properly when your mind is too scattered and paranoid to even focus on the wanking
Whereas sometimes I would snort or eat some and when I got the dosage right (and avoided the intense compulsion to do moar and moar and the strong desire to vape it), it could be a very prosexual experience with almost a rolly/mdma tinge to its effects.
For me It was almost always better on day two or three as well, the first day was always too physically stimulating with lots of anxiety. But then by day two you've developed some tolerance to those side effects so now the positives, like euphoria and prosexual effects, would seem to really shine.