Weed -> K2 -> salvia

[mtu mwendawazimu]

I think this is the progression for psychedelic effects.

Is there a reason for this?

Gets more chemically?

What's your experience?

 

[negrogesic]

Well synthetic cannabinoids are full agonists of cannabinoid receptors so they are much stronger than cannabis, and salvia works by a totally different (and far more horrifying) mechanism: kappa opioid receptor agonism.