Hello,
My name is Elliot Nelson, M.D. and I am a researcher at Washington University (email address: [email protected]). My colleagues and I are conducting a large genetic study of opioid misuse.
The rationale for the study is that individuals with a limited lifetime history of recreational opioid use are uniquely informative for identifying genetic variants that have protective effects. We particularly need to recruit adults (age 18 or older) who have misused opioids 60 times or fewer lifetime (including no opioid misuse for the past year). These individuals most typically have a history of heavier use of other substances such as alcohol, cocaine, stimulants, sedatives, or cannabis. We have no exclusions involving use of these other substances other than impairment at the time of the interview (and consent process).
We will compare these individuals to those with a history of daily opioid misuse that has lasted 6 months or longer. Because genetic studies require homogeneous groups, our sample is limited to individuals who are non-Hispanic and either black (of African American ancestry) or white (of European or European-American ancestry), and located in the United States or Canada. Our study was funded in 2017 and has just over a year remaining. We are still recruiting lower level misusers of either ancestral group and daily misusers of African American ancestry.
Participation involves a one-time, 1-3 hour telephone interview that asks about substance use, psychiatric illnesses and symptoms, and trauma exposure. Participants also provide a saliva sample as a source of DNA. We compensate participants with a $75 gift card for their time and inconvenience (available card choices include Amazon, Starbucks, Home Depot, and Subway) upon completion of the study.
Our study has IRB (Ethics) approval from the Washington University Human Research Protection Office. We understand the necessity of protecting the confidentiality of our participants. Interview and genetic data are stored under assigned numeric identifiers. All identifying information that we collect is securely stored separately from participants’ interview responses and genetic data. We have also obtained a Certificate of Confidentiality from NIH that confers some protection against subpoena.
Those potentially interested in participating can click this link https://redcap.wustl.edu/redcap/surveys/?s=4PCKKW7MRX to complete an initial self-screen and provide contact information. Further information about our study is available at our homepage: https://opioidmisusestudy.wustl.edu/ or via email ([email protected]).
My name is Elliot Nelson, M.D. and I am a researcher at Washington University (email address: [email protected]). My colleagues and I are conducting a large genetic study of opioid misuse.
The rationale for the study is that individuals with a limited lifetime history of recreational opioid use are uniquely informative for identifying genetic variants that have protective effects. We particularly need to recruit adults (age 18 or older) who have misused opioids 60 times or fewer lifetime (including no opioid misuse for the past year). These individuals most typically have a history of heavier use of other substances such as alcohol, cocaine, stimulants, sedatives, or cannabis. We have no exclusions involving use of these other substances other than impairment at the time of the interview (and consent process).
We will compare these individuals to those with a history of daily opioid misuse that has lasted 6 months or longer. Because genetic studies require homogeneous groups, our sample is limited to individuals who are non-Hispanic and either black (of African American ancestry) or white (of European or European-American ancestry), and located in the United States or Canada. Our study was funded in 2017 and has just over a year remaining. We are still recruiting lower level misusers of either ancestral group and daily misusers of African American ancestry.
Participation involves a one-time, 1-3 hour telephone interview that asks about substance use, psychiatric illnesses and symptoms, and trauma exposure. Participants also provide a saliva sample as a source of DNA. We compensate participants with a $75 gift card for their time and inconvenience (available card choices include Amazon, Starbucks, Home Depot, and Subway) upon completion of the study.
Our study has IRB (Ethics) approval from the Washington University Human Research Protection Office. We understand the necessity of protecting the confidentiality of our participants. Interview and genetic data are stored under assigned numeric identifiers. All identifying information that we collect is securely stored separately from participants’ interview responses and genetic data. We have also obtained a Certificate of Confidentiality from NIH that confers some protection against subpoena.
Those potentially interested in participating can click this link https://redcap.wustl.edu/redcap/surveys/?s=4PCKKW7MRX to complete an initial self-screen and provide contact information. Further information about our study is available at our homepage: https://opioidmisusestudy.wustl.edu/ or via email ([email protected]).
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