supersonic89
Bluelighter
- Joined
- Sep 17, 2019
- Messages
- 1,249
Hi Bluelighters.
Last night I take Chlorphenamine (a first-generation anti-histamine) for a mild allergy and according to Wikipedia, it also acts as a selective serotonin reuptake inhibitor (SSRI).
Well, I have some Tramadol pills and I wanted to take them tonight but I don't want a seizure or a serotonin syndrome . Considering this, would it be advisable not to take them, then? How long should I wait to take Tramadol?
Last night I take Chlorphenamine (a first-generation anti-histamine) for a mild allergy and according to Wikipedia, it also acts as a selective serotonin reuptake inhibitor (SSRI).
In addition to acting as an inverse agonist at the H1 receptor, chlorphenamine has been found to act as a serotonin reuptake inhibitor (Kd = 15.2 nM for the serotonin transporter).[8][21] It has only weak affinity for the norepinephrine and dopamine transporters (Kd = 1,440 nM and 1,060 nM, respectively).[8] A similar antihistamine, brompheniramine, led to the discovery of the selective serotonin reuptake inhibitor (SSRI) zimelidine.
Chlorphenamine - Wikipedia
en.wikipedia.org
Well, I have some Tramadol pills and I wanted to take them tonight but I don't want a seizure or a serotonin syndrome . Considering this, would it be advisable not to take them, then? How long should I wait to take Tramadol?