Tobacco and Caffeine Half-Life?

[PeaceOfPast]

I read somewhere on Erowid that the half-life of caffiene depends on if the person smokes. Is it the nicotine in the tobacco that decreases the half-life or some other alkaloid? Does that mean a ciggarette decreases the effect of caffiene?

 

[Black]

smoking tobacco induces CYP1A2 (apparently it's not the nicotine but other constituents of tobacco smoke but polycyclic aromatic hydrocarbons), which metabolises caffeine among other drugs. i don't think one cigarette will have any noticable effect, but being a smoker surely makes a difference.

 

[PeaceOfPast]

^Source?