I have done this successfully a few times by myself, but it's not easy. Starting again was stupid. It's easier than tapering from Suboxone though. Anyways, I was wondering if any seasoned users had tips on doing so. My usage has been as high as 250mg/day. One of the biggest issues is when you get down to doses below 10mg (I'm IV'ing by the way) the half life is so short that 90 min. later you are craving it again. What is the best way to space out doses? More in the morning so that you can function during the day, or more at night so you sleep better? Is it better to take 15mg twice daily or space it out to 3 or 4 doses/day. Twice daily your body has more time in between to detox from the drug, but yet you have higher serum concentration levels than 3-4 times/day dosage. Which is better for a goal of stopping?
I have not tried this, but maybe taking a h2 histamine antagonist such as cimetidine will decrease the half life a bit and make it easier at the lower doses. This inhibits the liver enzymes that break down the drug, the same effect as taking grapefruit juice.
Although the physical symptoms cannot be ignored, a lot of it is mental. You have taken enough to get rid of all the withdrawals, but yet you still want more. Also, it's a little like smoking as there are certain times or rituals that are associated with taking the drug and make you crave it.
Also, what about IM'ing? I've only done this a couple times when I was in a super rush and could not hit a vein immediately. I realize that nobody in a harm reduction forum can condone this method and I know all the risks, i.e. infection, abscess, botulism, tetanus, limb amputation, and it goes on. However, does anybody have any experience with doing this? This will make a low dose ultimately last longer. Perhaps doing this for the last few doses.
Although I have never tried this my Sub doctor many years ago suggested that when on your lowest bupe taper, say you've been on 0.25mg for a week, you take one high dose of 4 to 8mg and this floods the receptors and the body breaks the drug down and the long half life of the drug naturally tapers you off. This was a theory floating around medical circles at the time but I could never find anything about it. IF it does help I wonder if there is a similar effect for heroin.
I have not tried this, but maybe taking a h2 histamine antagonist such as cimetidine will decrease the half life a bit and make it easier at the lower doses. This inhibits the liver enzymes that break down the drug, the same effect as taking grapefruit juice.
Although the physical symptoms cannot be ignored, a lot of it is mental. You have taken enough to get rid of all the withdrawals, but yet you still want more. Also, it's a little like smoking as there are certain times or rituals that are associated with taking the drug and make you crave it.
Also, what about IM'ing? I've only done this a couple times when I was in a super rush and could not hit a vein immediately. I realize that nobody in a harm reduction forum can condone this method and I know all the risks, i.e. infection, abscess, botulism, tetanus, limb amputation, and it goes on. However, does anybody have any experience with doing this? This will make a low dose ultimately last longer. Perhaps doing this for the last few doses.
Although I have never tried this my Sub doctor many years ago suggested that when on your lowest bupe taper, say you've been on 0.25mg for a week, you take one high dose of 4 to 8mg and this floods the receptors and the body breaks the drug down and the long half life of the drug naturally tapers you off. This was a theory floating around medical circles at the time but I could never find anything about it. IF it does help I wonder if there is a similar effect for heroin.
