The Tina Trial: A new clinical trial for methamphetamine dependence (Geelong, Brisbane, Perth, Wollongong)

TinaTrial

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The Tina Trial is a clinical trial designed to see whether mirtazapine, an antidepressant medication, can help people reduce their use of methamphetamine (ice, crystal meth). Two previous small trials in the USA found that mirtazapine helped people to reduce their methamphetamine use and improved their mood. We want to find out whether mirtazapine can be used in routine clinical care in Australia.

The trial has been funded by the Medical Research Future Fund and is being conducted by researchers and clinicians across Australia and in the USA. Further information about the team can be found here. The information below is for people interested in participating in the trial and their friends and family.

The trial has been approved by the University of Wollongong Human Research Ethics Committee #2021/ETH12037

What is involved in participating?​

If you are interested in the trial, we start by assessing whether this trial is right for you. This will involve asking some questions over the phone, and then doing a more comprehensive face-to-face survey and a medical assessment. We may suggest other treatments instead of the trial. If you enrol in the trial, you will be given the trial medication to take home. You will be asked to take one tablet each evening for 16 weeks. The tablet will contain either mirtazapine or be a placebo tablet. You will have a 50% chance of receiving mirtazapine and a 50% chance of receiving the placebo. You will not know which one you will be taking.

During the trial we will meet with you regularly to monitor your health (these assessments take about 45 minutes each). There are ten assessments all up, and you will be involved in the trial for about five months. The first assessment will be done at your local clinic. After that, we can meet you at a more convenient location and we can also do some assessments by phone or zoom if you prefer. You will be reimbursed for each assessment. You can continue to receive whatever other treatments you need, provided that they do not compromise your safety or prevent you from participating in the trial assessments. You can also decide to stop the medication if you don’t like it, or withdraw from the study entirely.

If you are interested in participating, please get in touch and we can tell you more about what the trial involves. We will keep all your information confidential.

The Tina Trial is NOW OPEN for recruitment (until 2024) in Geelong, Wollongong, Perth, and Brisbane. We are currently seeking adult participants (18-65) who are regularly using methamphetamine.

If you would like more information or are interested in participating, more info can be found at www.tinatrial.info or you can also Register here.

Alternatively, you can contact your location researcher below:

Tina Trial Geelong: Contact Caity or Anna
Phone: 0432236786
Email: [email protected]

Tina Trial Wollongong: Contact Tamsin or Emma
Phone: 0434266371
Email: [email protected]

Tina Trial Perth: Contact Lily
Phone: 0432271460
Email: [email protected]

Tina Trial Brisbane: Contact Joel
Phone: 0434693616
Email: [email protected]
If you are interested in participating, use the QR code below to register on our website, or contact your location researcher below:
 
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