JohnBoy2000
Bluelighter
- Joined
- May 11, 2016
- Messages
- 2,465
Cymbalta is approved for treatment of pain conditions.
Some people swear by it - say it's the best.
What is the underlying pharmacodynamic action that incites this pain release?
Effexor is also used in this capacity.
Each act on serotonin, and noradrenaline.
But no serotonergic agent is approved for pain disorders - where there are plenty of tricyclics that are.
So - by logic - it must be noradrenaline, no?
So - would something like reboxetine theoretically work for someone being treated for pain with cymbalta??
Some people swear by it - say it's the best.
What is the underlying pharmacodynamic action that incites this pain release?
Effexor is also used in this capacity.
Each act on serotonin, and noradrenaline.
But no serotonergic agent is approved for pain disorders - where there are plenty of tricyclics that are.
So - by logic - it must be noradrenaline, no?
So - would something like reboxetine theoretically work for someone being treated for pain with cymbalta??