I recently used DMT orally via the following regimen:
0:00 200 mg Harmaline
0:20 75 mg yellow powdered DMT (at least slightly impure)
0:50 1 bowl cannabis
It was an excellent experience. The come-up was very long, slow, and smooth, with the peak starting somewhere around 1:30. The peak lasted for about four hours and included strong, colorful OEV and CEV, introspection, barely controllable laughter, and alternating between the urge to dance and the urge to lie still. Aftereffects lasted for at least a couple of hours.
I had to avoid a few troubling thoughts about stressors in my life, but that was down to my imperfect mindset at the time. I remember experiencing some mild nausea and body load, but was overall very comfortable throughout. A friend who was in a better mindset and followed the same dosing regimen experienced no discomfort at all.
I didn't get the mind-blowing dissociation often associated with DMT, but the experience felt very full and satisfactory nonetheless. If I repeat it, I'll probably use the same dose.