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sexual dysfunction from effexor overdose

stillcloudstill

Greenlighter
Joined
Dec 11, 2012
Messages
32
I've posted in the basic, other drugs forum for help, but it was not about advanced insights into specific drugs/supplements/theories/ideas, so here we go:

I take like a huge handful of fish oil each morning. One morning, a year and a half ago, I was groggy, and accidentally put a decent handful of Effexor XR 325mg pills down my throat. It may have been around 1500mg.

Ever since this day, I have been unable to have much sexual interest at all (masturbation is an utter chore, something I only do if I think it might help rehabilitate my neural pathways or something, but it's not fun, although I do orgasm with normal amounts of seminal fluid). I get only weak erections, nothing standing straight, making intercourse impossible. 20mg or more of Cialis does not change this.

I've heard of a new discovery in Israel for ED (erectile dysfunction) involving having thousands of microscopic vibrations pulsate through the penis for like 20 minutes to great success, but no news yet on exporting this research/equipment to anywhere else. There's Uprima, which works only if you have an arousal problem, not a blood circulation problem, but I haven't tried it. It's a dopamine agonist approved for sexual dysfunction by Abbott.

The thing is, I think the circuitry is all changed now, so even such drugs won't do anything-- see, I use to get hypersexuality when I took higher doses of Adderall (to do papers) and at night, go from one thought to another, manic-like, at these higher doses. Now, I have so sexual interest, no matter how much Adderall I take, or mania-like feelings while on it, ever since the day I took the Effexor overdose. I never went to the hospital over my overdose, as no signs of overdose like clammy skin or anything occurred, although black matter was excreted through my skin in my hands and arms. It looked like tiny, tarred pieces of shredded paper. Like dead brain cells, almost. Or maybe, I mean what else could it be? Cells do excrete waste products, after all, and it occurred within 1 hour of ingestion of the toxic amount of Effexor. I also felt severely diminished IQ for a couple of months or so, and the week that it happened, I was taken to a strip club and couldn't get an erection from lap dances. Still couldn't, for sure.

anyhow, I'm out of options, the sexual medicine clinic I go to is attached to a teaching hospital, but they never see this, they already ignore post-SSRI sexual dysfunction, thinking it's just a matter of time to wait out before things are resorted. I don't consider this PSSD, I consider it overdose-induced, and unlikely to ever repair itself.

I went to an endocrinologist, hoping testosterone might do the trick, but she wouldn't give me any, saying my testosterone was mid-normal for my age, and giving too much risks cancer. Isn't there some case of trying out, say, enough to give me high-normal amounts? I don't know, but someone on this board said he had PSSD, until he took testosterone, and then was fine.

If anyone is bored or in the same boat I'm in, please help with research. For instance, what is it about a dopamine agonist like Uprima that would change dopamine differently than my Adderall already does? Because it's used for other conditions, and in heroin addicts, has altered the wiring of addicts so they lose their addiction, according to Burroughs (don't see your hopes up high if you're addicted-- research is inconclusive about this, but it worked for him after 4-5 days and trying everything else). It does something about changing the way dopamine is processed, from what I read on wikipedia, but I can't put my finger on it.

anyhow, it seems like there's no answers. I just wish urologists and neurologists/psychiatrists got together and did something, because this is also caused by things like prostrate cancer treatment, etc.

From what I understand about injections into the penis, and products like Muse that you insert into your euthera, they start erections that don't go away for 30 minutes, even if you wanted to. So even if I discretely injected in the bathroom one of these drugs, it takes a lot of explaining to do to explain why I have an erection after the orgasm I faked (I usually faked orgasms when I had sex, because I either had a mental block on things, or it would take too long, or both).

So I'm 22, and am looking at prosthetic penile implant devices. I don't know what else to do. I don't know if there's research around something that's right around the corner, or if there's nothing around the corner. It seems neurological, though. I just hope my partner won't notice my implant device if I got one. It's got a switch between the bottom underside of the part leading up to the penis, before it meets the balls, but in some models, accidental inflation (erection) can occur while your pants are on and in public.

I heard on this board a former chronic meth user, a lawyer, had to resort to implanting one after using meth every night for like a year. Fried his dopamine receptors, I guess.

anyway, please help, I want to find a girl and marry one day. I'm a nice guy, women like me, I just want to make someone happy and not be alone for the rest of my life.
 
I think the circuitry is all changed now,

That's very unlikely. To me, it sounds like psychogenic anxiety. Sometimes people get long-lasting anxiety after drug overdoses, esp. serotonergics. Look at the neverending parade of people who take one dose of MDMA and then figure they have "permanently roasted their serotonin system forever". Reality check: their serotonin neurons are functioning just fine. Nobdoy ever climbs into a fMRI scanner to verify anyway, it is always 100% anecdotal.

My advice: calm down and stop feeling pressured to be sexually active, if your body doesn't want to respond the "correct way". It's a sign. Perhaps if you take it slow and intimate, rather than jacking off/taking Cialis/going to strip bars. Not every male is a hypersexual conqueror.

Move to SLR, this is not really an advanced drugs topic.
 
Have you tried taking a benzo or something? That would provide a decent idea as to whether or not it is anxiety related.

It could be possible to fuck up your serotonin system, but I don't think a one-off accident would do it.
The drug is long out of you, and you've had plenty time to recover.

You don't say whether you were hospitalized for this overdose. Were you?

I wouldn't put much hope in something like Uprima. However, I did find that pramipexole made me hypersexual. If you're not prone to that, it may bring something else out of you, that's hard to predict. You may blow your cash on strippers or blackjack. Apomorphine has too short of a half-life and is too prone to nausea- pramipexole is a better choice, and easier to get (Apomorphine is not approved for this use in the US, not that pramipexole is, but maybe you just happen to get a case of RLS, I dunno).

Have you had a testosterone level checked? Oh re-read. If testosterone is normal, it's normal. Going up won't offer much in the way of benefit, and will be sure to cause lots of problem. Fuck cancer, man-tits, acne, being a douche, liver, etc.

Are you on any other drugs? Re-Read. Adderall. How much do you take? How do you take it? Orally, or are you blowing lines? Perhaps sticking it in your ass? ;) This may be counter-intuitive, but your Adderall could be the problem. I have definitely noticed that my erections haven't been as strong when I'm on speed. Makes sense, vasoconstriction isn't conducive to a strong erection. You need the corpus cavernosum to swell with blood, which is caused by vasodilation. Speed may make you horny (or not, it does me), but if it's not producing the benefits you desire, try a couple weeks without it.

Do you have a girlfriend? Have you talked to her about your problem and your concerns? have you had a partner say something?

When you say you're faking orgasms because it's taking too long to finish. How long is too long? Are you talking more than an hour? More than two? Opiates pretty much guarantee that I'll be unable to orgasm. Rock hard erection and all, but no pleasurable finish (not without rubbing myself raw, truly).

Have you had a girl complain that you were taking too long? I've never had that complaint unless I break the 2 hour mark (even without opiates, I can go two or three hours if I want to- when I first started having sex I did have trouble finishing from oral sex, and did get complaints when I couldn't finish after 20 minutes, but hey, I was 16 and fuck it- I used it as an excuse to talk her into fucking me proper). I'm assuming that you were using a condom? It's difficult to fake an orgasm without one- unless you're willing to say, huh, well, I've been jerking it a lot lately, yeah... nothin' left!



Try not to worry about it though- sex is supposed to be fun. Try some different things. If you're not in a committed, stable relationship, you're going to have problems in this area, I'm afraid. You want someone you can learn and explore with, not some girl you will rapidly undress, screw for 10 minutes, get your things and run. To me that sounds great and all (well, add 35 minutes and her best friend) but it's not the thing that's going to work for you, I can almost guarantee. I don't want to sound corny, but a relationship is really essential for a fulfilling sex life. And you can always sleep with other girls, too, if you need more variety. Who is going to do your laundry? ;)

consider this: http://www.youtube.com/watch?v=2g4SSIf6Saw
you're better than this: http://www.youtube.com/watch?v=VLnWf1sQkjY
 
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