Saline can partially neutralize melanotan 2..... (+ some peptides)?

JohnBoy2000

JohnBoy2000

Bluelighter
Joined
May 11, 2016
Messages
2,465
I had been shocked previously to find out that mixing Botox with bac water (i.e. some alcohol) depletes its effectiveness;

And should be mixed exclusively with Saline.

Recently:

Be aware that some peptides, including I believe Melanotan 2, are acetate based, and saline can cause a reaction causing sodium acetate to precipitate, destroying some of the peptides and reducing the effectiveness. I noticed this when using PT141 with a .9% saline with .9% BA water. It didn’t fully dissolve and there were hard flakes of an off-white color.
Click to expand...
(taken from meso)

There appears to be a case, that saline can impact the effectiveness of melanotan 2, can be impacted by mixing it with saline;

And should mixed exclusively with bac water.

........

After a couple years of mixing with saline, I'm not using purified preserved water exclusively, and await to see what happens re efficacy.

I had thought I developed an mt2 tolerance after 12 straight of daily usage (albeit at 50 mcg), which I was doing to benefit from the oxytocin effect with pinned subQ (versus nasal spray, which doesn't have that effect).

The latter may still be the case.

But I sincerely hope the former is a better explanation, cause switching from saline to purified water is a much easier problem to solve, than trying to reverse an overuse cellular tolerance.

I'm open to scientific suggestion from the learned minds of this sub.
 
www.uk-muscle.co.uk

Mt2 stopped working (again)

As the title says. I’ve been using this peptide for most of the last ten years. It stopped working for me a few years back and it seemed no matter what supplier I tried, it just wouldn’t work. I, and other users in the old Melanotan forums started to think immunity to the peptide was possible...
www.uk-muscle.co.uk www.uk-muscle.co.uk

not using the sterile/saline solution they provide as that stuff makes it degrade so much faster then bac water,
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Just going to update this thread with interesting finding from melanotan users from this year:



Melanotan 1 in a nasal spray bottle caused kidney issues.

.........

I used too much mt 2, nasally administered last week and got the heaviest sides I've felt:

- heavy flushing
- 130 BPM heart rate.
- dizziness.
- curiously no nausea at all, or stomach cramping.

Effect on the heart is very real I believe.
 

Be aware that some peptides, including I believe Melanotan 2, are acetate based, and saline can cause a reaction causing sodium acetate to precipitate, destroying some of the peptides and reducing the effectiveness. I noticed this when using PT141 with a .9% saline with .9% BA water. It didn’t fully dissolve and there were hard flakes of an off-white color.
Click to expand...
 
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