Resetting your Tolerance?

[Nanneelix]

Is it possible to reset your body to the tolerance it was when first started doing opiods? I have had no meds for 2 weeks, except Gabapentin, Tizanadine, Meloxicam, and Imodium (no Imodium since last Wed). So is it possible that my tolerance will have dropped in that length of time? I was taking Oxycodone 10/325, 6 - 8 a day. I have a script for them 180 per 30 days. I get my new script on Saturday. I do legitimately need them for a back injury from a car accident in 2010. But as my tolerance has grown I've run out sooner than I should have. I'm hoping that by not having them for almost 2 weeks that I reset my clock so to speak. Thanks for any knowledge from anyone!!

 

[T. Calderone]

I used to run out early so much that I was off oxycodone more than on. It wasn't until I quit for a good couple months did tolerance reset. Every person is different though. What you can try is rotating the oxy with your other meds so you won't take so many.

 

[xZeroxCoolx]

Have you been in withdrawals for those 2 weeks?? If not I suggest getting off the oxycodone ASAP.. you?re on a slippery slope right now and can either turn into a lifetime opiate addict or can stop now and walk away without withdrawals.

If I had it to do over I would have never filled that first Norco prescription. 15 years later I?m still an opiate addict.

I know I went off topic here.. but this is honest advice for ya that I wish someone would have said to me.

 

[Jekyl Anhydride]

The use of NMDA antagonists has shown promise for keeping one's tolerance low during use but resetting is a different story. T Calderone's suggestion of a couple months has always worked for me but use caution if you have more than a couple weeks clean and try to go back to using the amounts you did before cessation as even a short period can make a difference in some.

NMDA-antagonists-for-tolerance-a-collection-of-the-evidence-and-anecdotal-reports

Regulation of μ-opioid receptors

 

[Nanneelix]

Yes I've been in withdrawal these 2 weeks. I have been on norco 5, 7.5, and 10 mg and then switched to 10mg percocet. I have been on them since 2010 for a severe back injury from a car accident. The last 2 months I have run out early. Last month was just a couple of days and I had some suboxone so I didn't go into withdrawals. This month I have been out 2 weeks. Gabapentin, Tizanadine, Meloxicam, to get thru, it's not been horrible, but not comfortable for sure! As I'm sure you totally understand ?