• N&PD Moderators: Skorpio | thegreenhand

Questions for the fun of it.

MedicinalUser247

Bluelighter
Joined
Aug 2, 2023
Messages
857
Explain molecular computation. Explain orbital theory. How many D receptors are there in the brain ? How many 5ht receptors are there in the brain ? Explain CYP metabolism. Besides Freud what do you think of Pavlov, Skinner, Thorndike and other psychologist ? And... Does marijuana effect the 5ht2 in certain people ?
 
Sure... Let me just finish up the 100-page answer to your questions.

However, you didn't say please. So maybe try asking chatgpt instead.
 
Let's take a crack at this.
> Explain molecular computation.
"Molecular computing is a branch of computing that uses DNA, biochemistry, and molecular biology hardware, instead of traditional silicon-based computer technologies."[ref]

> Explain orbital theory.
Electrons don't exist in nice circular orbits or shells, instead they have funny shaped "clouds" called orbitals where they are likely to be. The shape of these orbitals defines how atoms form bonds between each other and how reactions occur.

> How many D receptors are there in the brain ?
Well, there are 5 major types, D1, D2, D3, D4, and D5.
If you mean number of receptors total? A lot. Each nerve cell can have several types of receptors on it, and of each of those types, they can occur multiple times on a cell. So a certain nerve cell may have four or more D3 receptors, maybe some adenosine A2a receptors, some serotonin receptors, etc.
There are apparently 86 billion neurons in the human brain.[ref]. So "do the math, soldier!" The answer I get is roughly a shitload.

> How many 5ht receptors are there in the brain ?
This has the same answer as above,

>Explain CYP metabolism.
"The cytochrome P450 (CYP) enzymes are membrane-bound hemoproteins that play a pivotal role in the detoxification of xenobiotics, cellular metabolism and homeostasis. " [ref]
Basically, they're the family liver enzymes that do a lot of metabolic heavy lifting, generally deactivating drugs and turning compounds into more water soluble and hence easily excreted forms.

> Besides Freud what do you think of Pavlov, Skinner, Thorndike and other psychologist ?
This is not really a pharmaceutical question, but they did some pretty foundational research in the field that is still useful today.

> Does marijuana effect the 5ht2 in certain people ?
It has been shown to upregulate 5HT2A in a recent study but I don't think any cannabinoids activate 5HT2 receptors directly. Although, CBD does activate 5HT1A,[ref].
 
Top