It depends on the drug usually. For opiate antagonists id imagine it’s similar to opiate withdrawal. Detoxing is some really hard shit, physically and emotionally. First 48 hours you will feel intense goosebumps, cold sweats, inability to eat, and some nausea. Around the 72 hour mark it gets a bit worse. If your addiction isn’t as severe you may not have as painful as a time compared to a long term addict. I just got done withdrawing from fentanyl lol.
But essentially yes, if you can stick it out, after the first couple days/week you’ll be clean and done detoxing. Weening off is the only thing aside from benzos rhad will mitigate withdrawal symptoms. Mentally and emotionally is a different story. Your safest bet is weening off with the help of friends of family. It’s hard to do alone. If you cant do that, there are methadone and suboxone clinics. If you go to the ER you’ll probably catch covid 19 lol.