(zonk)
Bluelighter
- Joined
- May 24, 2008
- Messages
- 687
Have there been any pharmacological studies regarding positional isomers of phenylhexylamines? For instance...
Since propyls seem to replace carboxylates in some cocaine like substances and beta-methylphenethylamine is orally active stimulant with some dopaminergic activity, increasing the beta-alkyl chain seems to increase the dopaminergic affinity as seen with all the benzhydryl/pipradrol compounds, maybe a butyl will be Akin to an acetate as in methylphenidate? This compound would be 2-phenylhexylamine
1-phenylhexylamine is the non ring closed analog of phencyclidine like compounds, I'm fairly sure it's been covered and don't remember it being referred to as very active however to see if my memory serves correctly I couldn't locate any info in google...
4-phenylhexylamine may also be stimulatory however now the propyl would be short an alkyl which I suppose is better than short 2 alkyls but the positioning may make it more of an opioid which I suppose to some isn't a bad thing.
3,5 and 6, would any of these be stimulatory or serotogenic or whatever???
Of course all this is speculation on my part, just wondering if there's any data out there...
Since propyls seem to replace carboxylates in some cocaine like substances and beta-methylphenethylamine is orally active stimulant with some dopaminergic activity, increasing the beta-alkyl chain seems to increase the dopaminergic affinity as seen with all the benzhydryl/pipradrol compounds, maybe a butyl will be Akin to an acetate as in methylphenidate? This compound would be 2-phenylhexylamine
1-phenylhexylamine is the non ring closed analog of phencyclidine like compounds, I'm fairly sure it's been covered and don't remember it being referred to as very active however to see if my memory serves correctly I couldn't locate any info in google...
4-phenylhexylamine may also be stimulatory however now the propyl would be short an alkyl which I suppose is better than short 2 alkyls but the positioning may make it more of an opioid which I suppose to some isn't a bad thing.
3,5 and 6, would any of these be stimulatory or serotogenic or whatever???
Of course all this is speculation on my part, just wondering if there's any data out there...