First off if they did not come directly from a pharmacy you should be aware that bunk pills containing fentanyl and fentanyl analogs are becoming commonplace and in which case a fraction of one of those pills could cause you to OD. Secondly, while the 325/650mg of acetaminophen is within normal amounts for consumption, it is particularly taxing on the liver. Without knowing exactly what your liver problem is and what your opioid tolerance level is then it's difficult to say what dose is safe for you. If you had no liver issues and no tolerance than I'd say try one and if you aren't feeling too sedated, nauseated, itchy, etc, after an hour then take the second. Your liver issues are concerning though and while a CWE on such a small amount may cause you to lose some, it may be essential in your case.